AU2020215729B2 - Enhanced nitrate compositions and methods of use - Google Patents

Enhanced nitrate compositions and methods of use Download PDF

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Publication number
AU2020215729B2
AU2020215729B2 AU2020215729A AU2020215729A AU2020215729B2 AU 2020215729 B2 AU2020215729 B2 AU 2020215729B2 AU 2020215729 A AU2020215729 A AU 2020215729A AU 2020215729 A AU2020215729 A AU 2020215729A AU 2020215729 B2 AU2020215729 B2 AU 2020215729B2
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AU
Australia
Prior art keywords
elemental
nitrate anion
nitrate
composition
source
Prior art date
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AU2020215729A
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English (en)
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AU2020215729A1 (en
Inventor
Ronald Kramer
Alexandros Nikolaidis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermolife International LLC
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Thermolife International LLC
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Publication date
Application filed by Thermolife International LLC filed Critical Thermolife International LLC
Publication of AU2020215729A1 publication Critical patent/AU2020215729A1/en
Application granted granted Critical
Publication of AU2020215729B2 publication Critical patent/AU2020215729B2/en
Priority to AU2023203649A priority Critical patent/AU2023203649B2/en
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Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
AU2020215729A 2019-02-01 2020-01-31 Enhanced nitrate compositions and methods of use Active AU2020215729B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023203649A AU2023203649B2 (en) 2019-02-01 2023-06-12 Enhanced nitrate compositions and methods of use

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962800361P 2019-02-01 2019-02-01
US62/800,361 2019-02-01
US201962866540P 2019-06-25 2019-06-25
US62/866,540 2019-06-25
US16/779,349 2020-01-31
PCT/US2020/016274 WO2020160509A1 (en) 2019-02-01 2020-01-31 Enhanced nitrate compositions and methods of use
US16/779,349 US20200222449A1 (en) 2019-02-01 2020-01-31 Enhanced Nitrate Compositions and Methods of Use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2023203649A Division AU2023203649B2 (en) 2019-02-01 2023-06-12 Enhanced nitrate compositions and methods of use

Publications (2)

Publication Number Publication Date
AU2020215729A1 AU2020215729A1 (en) 2021-09-02
AU2020215729B2 true AU2020215729B2 (en) 2023-03-30

Family

ID=71517286

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2020215729A Active AU2020215729B2 (en) 2019-02-01 2020-01-31 Enhanced nitrate compositions and methods of use
AU2023203649A Active AU2023203649B2 (en) 2019-02-01 2023-06-12 Enhanced nitrate compositions and methods of use

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2023203649A Active AU2023203649B2 (en) 2019-02-01 2023-06-12 Enhanced nitrate compositions and methods of use

Country Status (12)

Country Link
US (5) US20200222449A1 (https=)
EP (1) EP3917543A4 (https=)
JP (1) JP7534310B2 (https=)
KR (1) KR102789451B1 (https=)
CN (1) CN113498345A (https=)
AU (2) AU2020215729B2 (https=)
BR (1) BR112021015110A2 (https=)
CA (1) CA3128232A1 (https=)
EA (1) EA202192132A1 (https=)
IL (1) IL285247A (https=)
MX (1) MX2021009287A (https=)
WO (1) WO2020160509A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
US12612370B2 (en) 2011-03-02 2026-04-28 Thermolife International, Llc Amino acid compositions
WO2022192743A1 (en) * 2021-03-11 2022-09-15 Thermolife International, Llc Enhanced nitrate, elemental metal, and amino acid compositions and methods of use
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches
WO2022174116A1 (en) * 2021-02-11 2022-08-18 Thermolife International, Llc A method of administering nitric oxide gas
JP2024541338A (ja) * 2020-11-12 2024-11-08 サーモライフ インターナショナル， エルエルシー 血中酸素飽和度を増大させる方法
AU2022220004A1 (en) * 2021-02-11 2023-08-17 Thermolife International, Llc A method of administering nitric oxide gas
JP2024508952A (ja) * 2021-03-11 2024-02-28 サーモライフ インターナショナル， エルエルシー ニトレートと単体金属とアミノ酸との増強された組成物ならびに使用方法
CA3226249A1 (en) * 2021-08-16 2023-02-23 Thermolife International, Llc Iron supplement compositions and methods of use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040058011A1 (en) * 2002-09-20 2004-03-25 Petersson Lennart G. Powder teat dip germicide, fungicide and skin conditioner
US20110123654A1 (en) * 2008-06-06 2011-05-26 Ralf Jaeger Synergistic enhancement of cellular ergogenic nutrient uptake, like creatine or carnitine, with tarragon
US20180133247A1 (en) * 2016-11-15 2018-05-17 Berkeley Nox Limited Novel dietary supplements

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU476799B2 (en) * 1974-02-04 1976-08-05 Carlton And United Breweries Limited Preparation of a water soluble isomerised hop extract
US6703056B2 (en) * 2000-09-29 2004-03-09 The Procter + Gamble Co. Beverage compositions comprising arabinogalactan and defined minerals
CN100399948C (zh) * 2002-12-06 2008-07-09 协和发酵工业株式会社 含氨基酸的饮料和减少氨基酸苦味的方法
DK2124638T3 (en) 2007-02-26 2017-03-20 Heartbeet Ltd COMPOSITION INCREASING PERFORMANCE AND USING IT
US10646508B1 (en) * 2007-09-18 2020-05-12 Thermolife International, Llc Method of safely administering nitrate dietary supplements and compositions
US7777074B2 (en) 2007-09-18 2010-08-17 Thermolife International, Llc Amino acid compounds
US8303995B1 (en) * 2008-06-13 2012-11-06 Board Of Regents, The University Of Texas System Nitrite formulations and their use as nitric oxide prodrugs
ES2538652T3 (es) 2009-06-16 2015-06-23 Dusan Miljkovic Composiciones y procedimientos para producir un potencial negativo de oxidación-reducción estable en materiales consumibles
JP2014513527A (ja) 2011-04-21 2014-06-05 ネステク ソシエテ アノニム パフォーマンス向上のための栄養組成物並びにその作製及び使用方法
JP6016610B2 (ja) 2012-12-20 2016-10-26 江崎グリコ株式会社 筋肉増量用サプリメント
CA2965441C (en) * 2014-10-22 2020-03-24 Innoveco Australia Pty. Ltd. Process for metal extraction with sorption leaching in wet solids
ES2651717B1 (es) 2016-07-26 2018-11-16 Lara OLLER DUQUE Solución acuosa cristaloide isotónica
WO2020214841A1 (en) * 2019-04-16 2020-10-22 Thermolife International, Llc Hexylamine salts and methods of using hexylamine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040058011A1 (en) * 2002-09-20 2004-03-25 Petersson Lennart G. Powder teat dip germicide, fungicide and skin conditioner
US20110123654A1 (en) * 2008-06-06 2011-05-26 Ralf Jaeger Synergistic enhancement of cellular ergogenic nutrient uptake, like creatine or carnitine, with tarragon
US20180133247A1 (en) * 2016-11-15 2018-05-17 Berkeley Nox Limited Novel dietary supplements

Also Published As

Publication number Publication date
JP2022523513A (ja) 2022-04-25
EP3917543A4 (en) 2022-10-12
KR102789451B1 (ko) 2025-03-31
KR20210119499A (ko) 2021-10-05
US20200222449A1 (en) 2020-07-16
US20240122967A1 (en) 2024-04-18
EA202192132A1 (ru) 2021-10-19
AU2020215729A1 (en) 2021-09-02
AU2023203649B2 (en) 2024-11-14
CA3128232A1 (en) 2020-08-06
WO2020160509A1 (en) 2020-08-06
EP3917543A1 (en) 2021-12-08
US20240122968A1 (en) 2024-04-18
US20240122966A1 (en) 2024-04-18
US20240122969A1 (en) 2024-04-18
MX2021009287A (es) 2021-11-12
CN113498345A (zh) 2021-10-12
AU2023203649A1 (en) 2023-07-06
JP7534310B2 (ja) 2024-08-14
BR112021015110A2 (pt) 2022-01-11
IL285247A (en) 2021-09-30

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