AU2019250653A1 - A method of inducing or improving wound healing properties of mesenchymal stem cells - Google Patents

A method of inducing or improving wound healing properties of mesenchymal stem cells Download PDF

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Publication number
AU2019250653A1
AU2019250653A1 AU2019250653A AU2019250653A AU2019250653A1 AU 2019250653 A1 AU2019250653 A1 AU 2019250653A1 AU 2019250653 A AU2019250653 A AU 2019250653A AU 2019250653 A AU2019250653 A AU 2019250653A AU 2019250653 A1 AU2019250653 A1 AU 2019250653A1
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Australia
Prior art keywords
mesenchymal stem
cell population
stem cell
cells
umbilical cord
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Pending
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AU2019250653A
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English (en)
Inventor
Toan Thang Phan
Gavin TAN
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CellResearch Corp Pte Ltd
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CellResearch Corp Pte Ltd
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Application filed by CellResearch Corp Pte Ltd filed Critical CellResearch Corp Pte Ltd
Publication of AU2019250653A1 publication Critical patent/AU2019250653A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/395—Thyroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10—Mechanical dissociation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU2019250653A 2018-04-12 2019-04-12 A method of inducing or improving wound healing properties of mesenchymal stem cells Pending AU2019250653A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862656531P 2018-04-12 2018-04-12
US62/656,531 2018-04-12
PCT/SG2019/050204 WO2019199234A1 (en) 2018-04-12 2019-04-12 A method of inducing or improving wound healing properties of mesenchymal stem cells

Publications (1)

Publication Number Publication Date
AU2019250653A1 true AU2019250653A1 (en) 2020-10-15

Family

ID=68163253

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019250653A Pending AU2019250653A1 (en) 2018-04-12 2019-04-12 A method of inducing or improving wound healing properties of mesenchymal stem cells

Country Status (12)

Country Link
EP (1) EP3775163A4 (ja)
JP (2) JP2021526125A (ja)
KR (1) KR20200143399A (ja)
CN (1) CN112262211A (ja)
AU (1) AU2019250653A1 (ja)
BR (1) BR112020020092A2 (ja)
CA (1) CA3095490A1 (ja)
PH (1) PH12020551658A1 (ja)
SG (1) SG11202009687PA (ja)
TW (1) TW202012618A (ja)
WO (1) WO2019199234A1 (ja)
ZA (1) ZA202005967B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210140942A1 (en) * 2019-10-08 2021-05-13 Cellresearch Corporation Pte. Ltd. Method of assessing wound healing potency of a mesenchymal stem population and related methods of selecting mesenchymal stem cells and identifying tissue as starting material for producing a mesenchymal stem cell population
WO2021257073A1 (en) * 2020-06-17 2021-12-23 Joy Kong Method for producing mesenchymal stem cells from neonatal stem cells
WO2022004938A1 (ko) * 2020-06-30 2022-01-06 주식회사 미래셀바이오 유사 중간엽 줄기세포의 제조방법
CN114196626A (zh) * 2022-02-16 2022-03-18 北京国卫生物科技有限公司 脐带间充质干细胞及其分离培养扩增方法
WO2024107102A1 (en) * 2022-11-17 2024-05-23 Cellresearch Corporation Pte. Ltd. Use of conditioned medium derived from cultivation of mesenchymal stem cells of the umbilical cord for inducing, stimulating and promoting hair growth and regeneration

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101040042B (zh) * 2004-08-16 2013-06-19 细胞研究私人有限公司 自脐带羊膜分离干/祖细胞
CN101330935B (zh) * 2005-10-21 2013-11-13 细胞研究私人有限公司 自脐带羊膜分离和培养干/祖细胞及其分化的细胞的应用
JP4569711B2 (ja) * 2006-04-14 2010-10-27 和光純薬工業株式会社 複数溶液導入構造、該構造を有する微小流体装置及び溶液導入法
KR101138091B1 (ko) * 2011-08-31 2012-04-24 세원셀론텍(주) 중간엽 줄기세포 기본 배양 배지 조성방법, 중간엽 줄기세포 기본 배양 배지 및 이를 이용하여 배양분화된 세포치료제
CN104630142B (zh) * 2015-02-06 2018-06-05 广州赛莱拉干细胞科技股份有限公司 一种牛脐带间充质干细胞的分离及培养方法
EP3385368B1 (en) * 2015-12-03 2023-03-01 Takara Bio Inc. Method for producing mesenchymal stem cells
WO2017096607A1 (zh) * 2015-12-11 2017-06-15 郭镭 一种从脐带外层羊膜组织中分离提取hUC-MSC的方法
SG11201900753VA (en) * 2016-10-05 2019-02-27 Cellresearch Corp Pte Ltd A method of isolating mesenchymal stem cells from umbilical cord amniotic membrane using a cell culture medium
WO2019199230A1 (en) * 2018-04-09 2019-10-17 Cellresearch Corporation Pte. Ltd. A method of transporting mesenchymal stem cells by means of a cell culture medium and a method of administering stem cells to wounds

Also Published As

Publication number Publication date
KR20200143399A (ko) 2020-12-23
ZA202005967B (en) 2021-08-25
EP3775163A4 (en) 2022-03-09
TW202012618A (zh) 2020-04-01
JP2021526125A (ja) 2021-09-30
SG11202009687PA (en) 2020-10-29
CN112262211A (zh) 2021-01-22
JP2024069365A (ja) 2024-05-21
PH12020551658A1 (en) 2021-07-26
CA3095490A1 (en) 2019-10-17
BR112020020092A2 (pt) 2021-02-17
WO2019199234A1 (en) 2019-10-17
EP3775163A1 (en) 2021-02-17

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