AU2019228119A1 - Pharmaceutical compositions comprising nebivolol - Google Patents
Pharmaceutical compositions comprising nebivolol Download PDFInfo
- Publication number
- AU2019228119A1 AU2019228119A1 AU2019228119A AU2019228119A AU2019228119A1 AU 2019228119 A1 AU2019228119 A1 AU 2019228119A1 AU 2019228119 A AU2019228119 A AU 2019228119A AU 2019228119 A AU2019228119 A AU 2019228119A AU 2019228119 A1 AU2019228119 A1 AU 2019228119A1
- Authority
- AU
- Australia
- Prior art keywords
- nebivolol
- pharmaceutical composition
- present
- pharmaceutically acceptable
- liquid vehicle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229960000619 nebivolol Drugs 0.000 title claims abstract description 120
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- JWEXHQAEWHKGCW-VCVZPGOSSA-N (S,R,R,R)-nebivolol hydrochloride Chemical compound [Cl-].C1CC2=CC(F)=CC=C2O[C@H]1[C@H](O)C[NH2+]C[C@@H](O)[C@H]1OC2=CC=C(F)C=C2CC1 JWEXHQAEWHKGCW-VCVZPGOSSA-N 0.000 claims 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
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- Dispersion Chemistry (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862637676P | 2018-03-02 | 2018-03-02 | |
| US62/637,676 | 2018-03-02 | ||
| EP18159727.9 | 2018-03-02 | ||
| EP18159727 | 2018-03-02 | ||
| PCT/EP2019/055149 WO2019166631A1 (en) | 2018-03-02 | 2019-03-01 | Pharmaceutical compositions comprising nebivolol |
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| AU2019228119A1 true AU2019228119A1 (en) | 2020-09-10 |
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| AU2019228119A Abandoned AU2019228119A1 (en) | 2018-03-02 | 2019-03-01 | Pharmaceutical compositions comprising nebivolol |
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| US (1) | US11576893B2 (https=) |
| EP (1) | EP3758676A1 (https=) |
| JP (1) | JP7353292B2 (https=) |
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| IL (1) | IL276750A (https=) |
| MX (1) | MX2020009132A (https=) |
| SG (1) | SG11202007858VA (https=) |
| WO (1) | WO2019166631A1 (https=) |
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| ES2969758T3 (es) | 2016-09-22 | 2024-05-22 | Novaliq Gmbh | Composiciones farmacéuticas para usar en la terapia de la blefaritis |
| US10813976B2 (en) | 2016-09-23 | 2020-10-27 | Novaliq Gmbh | Ophthalmic compositions comprising ciclosporin |
| PT3399962T (pt) | 2016-12-23 | 2020-09-03 | Novaliq Gmbh | Composição oftálmica para o tratamento da doença do olho seco |
| CA3058097C (en) | 2017-04-21 | 2024-01-02 | Novaliq Gmbh | Iodine compositions |
| KR20200059272A (ko) | 2017-09-27 | 2020-05-28 | 노바리크 게엠베하 | 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물 |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
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| EP2944324A1 (de) | 2014-05-13 | 2015-11-18 | LTS LOHMANN Therapie-Systeme AG | Verwendung von semifluorierten Alkanen in transdermalen therapeutischen Systemen |
| CA2955425A1 (en) * | 2014-07-17 | 2016-01-21 | Jerome Schentag | Activation of the endogenous ileal brake hormone pathway for organ regeneration and related compositions, methods of treatment, diagnostics, and regulatory systems |
| JP6660939B2 (ja) | 2014-08-13 | 2020-03-11 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 点眼剤からの保存剤除去 |
| WO2016082644A1 (en) | 2014-11-26 | 2016-06-02 | The University Of Hong Kong | A semifluorinated alkane based cleaner for removing emulsified droplets in the eye to reduce the complications associated with the emulsification of silicone oil |
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| CN108348777B (zh) | 2015-09-30 | 2020-04-28 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
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| AU2017333420A1 (en) | 2016-09-28 | 2019-04-04 | Novaliq Gmbh | Compositions comprising a cannabinoid receptor binding ligand |
| EP3558308A1 (en) | 2016-12-22 | 2019-10-30 | Novaliq GmbH | Compositions comprising tacrolimus for the treatment of intraocular inflammatory eye diseases |
| PT3399962T (pt) | 2016-12-23 | 2020-09-03 | Novaliq Gmbh | Composição oftálmica para o tratamento da doença do olho seco |
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| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| KR102882058B1 (ko) | 2018-03-28 | 2025-11-07 | 노바리크 게엠베하 | 티몰롤을 포함하는 약제학적 조성물 |
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| EP3852734A1 (en) | 2018-09-22 | 2021-07-28 | Novaliq GmbH | Ophthalmic compositions for treatment of ocular surface damage and symptoms of dryness |
| SG11202102820VA (en) | 2018-10-12 | 2021-04-29 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
| US20220008397A1 (en) | 2019-01-21 | 2022-01-13 | Novaliq Gmbh | Pharmaceutical composition for the treatment of ocular neovascularisation |
-
2019
- 2019-03-01 EP EP19707393.5A patent/EP3758676A1/en active Pending
- 2019-03-01 US US16/977,368 patent/US11576893B2/en active Active
- 2019-03-01 JP JP2020545478A patent/JP7353292B2/ja active Active
- 2019-03-01 KR KR1020207027428A patent/KR20200128407A/ko not_active Ceased
- 2019-03-01 BR BR112020017838-1A patent/BR112020017838A2/pt not_active Application Discontinuation
- 2019-03-01 WO PCT/EP2019/055149 patent/WO2019166631A1/en not_active Ceased
- 2019-03-01 CA CA3091308A patent/CA3091308A1/en active Pending
- 2019-03-01 SG SG11202007858VA patent/SG11202007858VA/en unknown
- 2019-03-01 AU AU2019228119A patent/AU2019228119A1/en not_active Abandoned
- 2019-03-01 CN CN201980016425.2A patent/CN112135603B/zh active Active
- 2019-03-01 MX MX2020009132A patent/MX2020009132A/es unknown
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2020
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Also Published As
| Publication number | Publication date |
|---|---|
| IL276750A (en) | 2020-10-29 |
| JP2021515758A (ja) | 2021-06-24 |
| JP7353292B2 (ja) | 2023-09-29 |
| CN112135603A (zh) | 2020-12-25 |
| CA3091308A1 (en) | 2019-09-06 |
| KR20200128407A (ko) | 2020-11-12 |
| US20210106558A1 (en) | 2021-04-15 |
| EP3758676A1 (en) | 2021-01-06 |
| WO2019166631A1 (en) | 2019-09-06 |
| US11576893B2 (en) | 2023-02-14 |
| CN112135603B (zh) | 2024-04-16 |
| MX2020009132A (es) | 2020-12-11 |
| SG11202007858VA (en) | 2020-09-29 |
| BR112020017838A2 (pt) | 2020-12-22 |
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