AU2019212840B2 - Expression of metabolic modulators in tumor microenvironment to improve tumor therapy - Google Patents

Expression of metabolic modulators in tumor microenvironment to improve tumor therapy Download PDF

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AU2019212840B2
AU2019212840B2 AU2019212840A AU2019212840A AU2019212840B2 AU 2019212840 B2 AU2019212840 B2 AU 2019212840B2 AU 2019212840 A AU2019212840 A AU 2019212840A AU 2019212840 A AU2019212840 A AU 2019212840A AU 2019212840 B2 AU2019212840 B2 AU 2019212840B2
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tumor
protein
leptin
virus
cell
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AU2019212840A1 (en
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Greg M. Delgoffe
Dayana RIVADENEIRA
Padmavathi Sampath
Stephen H. Thorne
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University of Pittsburgh
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AU2019212840A 2018-01-26 2019-01-28 Expression of metabolic modulators in tumor microenvironment to improve tumor therapy Active AU2019212840B2 (en)

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US201862622547P 2018-01-26 2018-01-26
US62/622,547 2018-01-26
PCT/US2019/015434 WO2019148109A1 (en) 2018-01-26 2019-01-28 Expression of metabolic modulators in tumor microenvironment to improve tumor therapy

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AU2019212840A1 AU2019212840A1 (en) 2020-07-16
AU2019212840B2 true AU2019212840B2 (en) 2024-08-15

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US (1) US11786569B2 (https=)
EP (1) EP3720283A4 (https=)
JP (2) JP2021511060A (https=)
KR (1) KR102849901B1 (https=)
CN (1) CN111655845A (https=)
AU (1) AU2019212840B2 (https=)
CA (1) CA3087044A1 (https=)
WO (1) WO2019148109A1 (https=)

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EP3973973A1 (en) 2017-10-31 2022-03-30 KaliVir Immunotherapeutics, Inc. Platform oncolytic vector for systemic delivery
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
KR20220115569A (ko) 2019-11-18 2022-08-17 얀센 바이오테크 인코포레이티드 돌연변이 calr 및 jak2에 기반한 백신 및 이의 용도
US20220409684A1 (en) * 2019-11-18 2022-12-29 The Brigham And Women's Hospital, Inc. Codon optimized new generation regulatable fusogenic oncolytic herpes simplex virus type 1 virus and methods of use
US12295997B2 (en) 2020-07-06 2025-05-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
WO2022047220A1 (en) * 2020-08-27 2022-03-03 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Oncolytic viruses encoding recombinant tranforming growth factor (tgf)-beta monomers and uses thereof
CA3197371A1 (en) * 2020-11-19 2022-05-27 Kalivir Immunotherapeutics, Inc. Oncolytic immunotherapy by tumor micro-environment remodeling
EP4329786A4 (en) 2021-04-30 2024-12-11 KaliVir Immunotherapeutics, Inc. Oncolytic viruses for modified mhc expression
CN116286911A (zh) * 2022-10-21 2023-06-23 上海鑫湾生物科技有限公司 一种响应缺氧环境调控病毒复制的可剪接系统及其用途

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CN1252260C (zh) 2000-07-21 2006-04-19 上海三维生物技术有限公司 肿瘤特异性启动子
US8969291B2 (en) 2004-10-08 2015-03-03 Enzo Therapeutics, Inc. Methods for decreasing leptin levels or activity for treating inflammation
KR101542275B1 (ko) * 2007-11-19 2015-08-06 트랜스진 에스.에이. 폭스바이러스성 온콜리틱 벡터
CA2709292A1 (en) * 2009-07-10 2011-01-10 The Governors Of The University Of Alberta Oncolytic viruses and methods for treating neoplastic disorders
DK3169341T3 (da) 2014-07-16 2019-08-05 Transgene Sa Onkolytisk virus til ekspression af immun-checkpoint-modulatorer
HK1255192A1 (zh) 2015-09-08 2019-08-09 Sillajen, Inc. 表达细胞因子和羧酸酯酶的修饰的溶瘤痘苗病毒及其使用方法
KR102016128B1 (ko) * 2015-09-21 2019-08-29 주식회사 엘지화학 이차전지용 전극의 제조 방법 및 이에 따라 제조된 이차전지용 전극

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JP2021511060A (ja) 2021-05-06
EP3720283A1 (en) 2020-10-14
CA3087044A1 (en) 2019-08-01
KR102849901B1 (ko) 2025-08-22
JP2024029176A (ja) 2024-03-05
EP3720283A4 (en) 2021-09-08
KR20200116086A (ko) 2020-10-08
US20200330534A1 (en) 2020-10-22
AU2019212840A1 (en) 2020-07-16
US11786569B2 (en) 2023-10-17
CN111655845A (zh) 2020-09-11
WO2019148109A1 (en) 2019-08-01

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