AU2019212840B2 - Expression of metabolic modulators in tumor microenvironment to improve tumor therapy - Google Patents

Expression of metabolic modulators in tumor microenvironment to improve tumor therapy Download PDF

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AU2019212840B2
AU2019212840B2 AU2019212840A AU2019212840A AU2019212840B2 AU 2019212840 B2 AU2019212840 B2 AU 2019212840B2 AU 2019212840 A AU2019212840 A AU 2019212840A AU 2019212840 A AU2019212840 A AU 2019212840A AU 2019212840 B2 AU2019212840 B2 AU 2019212840B2
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tumor
protein
leptin
virus
cell
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AU2019212840A1 (en
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Greg M. Delgoffe
Dayana RIVADENEIRA
Padmavathi Sampath
Stephen H. Thorne
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University of Pittsburgh
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AU2019212840A 2018-01-26 2019-01-28 Expression of metabolic modulators in tumor microenvironment to improve tumor therapy Active AU2019212840B2 (en)

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US201862622547P 2018-01-26 2018-01-26
US62/622,547 2018-01-26
PCT/US2019/015434 WO2019148109A1 (en) 2018-01-26 2019-01-28 Expression of metabolic modulators in tumor microenvironment to improve tumor therapy

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AU2019212840B2 true AU2019212840B2 (en) 2024-08-15

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US (1) US11786569B2 (https=)
EP (1) EP3720283A4 (https=)
JP (2) JP2021511060A (https=)
KR (1) KR102849901B1 (https=)
CN (1) CN111655845A (https=)
AU (1) AU2019212840B2 (https=)
CA (1) CA3087044A1 (https=)
WO (1) WO2019148109A1 (https=)

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EP3703723A4 (en) 2017-10-31 2021-12-15 KaliVir Immunotherapeutics, Inc. ONCOLYTIC PLATFORM VECTOR FOR SYSTEMS ADMINISTRATION
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
CR20220220A (es) 2019-11-18 2022-09-20 Janssen Biotech Inc Vacunas basadas en calr y jak2 mutantes y sus usos
WO2021101796A1 (en) * 2019-11-18 2021-05-27 The Brigham And Women's Hospital, Inc. Codon optimized new generation regulatable fusogenic oncolytic herpes simplex virus type 1 virus and methods of use
EP4175664A2 (en) 2020-07-06 2023-05-10 Janssen Biotech, Inc. Prostate neoantigens and their uses
JP2023539195A (ja) * 2020-08-27 2023-09-13 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 組換えトランスフォーミング増殖因子（ｔｇｆ）－ベータ単量体をコードする腫瘍溶解性ウイルスおよびその使用
TW202227621A (zh) * 2020-11-19 2022-07-16 美商凱立凡爾免疫治療股份有限公司 重塑腫瘤微環境的溶瘤免疫療法
BR112023022681A2 (pt) 2021-04-30 2024-01-23 Kalivir Immunotherapeutics Inc Vírus oncolíticos para expressão modificada de mhc
CN116286911A (zh) * 2022-10-21 2023-06-23 上海鑫湾生物科技有限公司 一种响应缺氧环境调控病毒复制的可剪接系统及其用途

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JP4845327B2 (ja) * 2000-07-21 2011-12-28 千葉県 腫瘍特異的プロモーター
US8969291B2 (en) * 2004-10-08 2015-03-03 Enzo Therapeutics, Inc. Methods for decreasing leptin levels or activity for treating inflammation
HRP20150360T1 (hr) * 2007-11-19 2015-05-08 Transgene Sa Poksvirusni onkolitiäśki vektori
CA2709292A1 (en) 2009-07-10 2011-01-10 The Governors Of The University Of Alberta Oncolytic viruses and methods for treating neoplastic disorders
RU2696312C2 (ru) * 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
WO2017043815A1 (en) * 2015-09-08 2017-03-16 Sillajen, Inc. Modified oncolytic vaccinia viruses expressing a cytokine and a car- boxylesterase and methods of use thereof
KR102016128B1 (ko) * 2015-09-21 2019-08-29 주식회사 엘지화학 이차전지용 전극의 제조 방법 및 이에 따라 제조된 이차전지용 전극

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US20200330534A1 (en) 2020-10-22
EP3720283A1 (en) 2020-10-14
WO2019148109A1 (en) 2019-08-01
KR20200116086A (ko) 2020-10-08
KR102849901B1 (ko) 2025-08-22
JP2021511060A (ja) 2021-05-06
CN111655845A (zh) 2020-09-11
US11786569B2 (en) 2023-10-17
CA3087044A1 (en) 2019-08-01
EP3720283A4 (en) 2021-09-08
AU2019212840A1 (en) 2020-07-16
JP2024029176A (ja) 2024-03-05

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