AU2018322317B2 - Methods to improve organ viability - Google Patents

Methods to improve organ viability Download PDF

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Publication number
AU2018322317B2
AU2018322317B2 AU2018322317A AU2018322317A AU2018322317B2 AU 2018322317 B2 AU2018322317 B2 AU 2018322317B2 AU 2018322317 A AU2018322317 A AU 2018322317A AU 2018322317 A AU2018322317 A AU 2018322317A AU 2018322317 B2 AU2018322317 B2 AU 2018322317B2
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AU
Australia
Prior art keywords
ppm
organ
composition
gas
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2018322317A
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English (en)
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AU2018322317A1 (en
Inventor
Jim POTENZIANO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Pharmaceuticals Ireland Ltd
Original Assignee
Mallinckrodt Pharmaceuticals Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Mallinckrodt Pharmaceuticals Ireland Ltd filed Critical Mallinckrodt Pharmaceuticals Ireland Ltd
Publication of AU2018322317A1 publication Critical patent/AU2018322317A1/en
Assigned to MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED reassignment MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED Request for Assignment Assignors: Mallinckrodt Hospital Products IP Limited
Application granted granted Critical
Publication of AU2018322317B2 publication Critical patent/AU2018322317B2/en
Priority to AU2024200468A priority Critical patent/AU2024200468A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00969—Surgical instruments, devices or methods used for transplantation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
AU2018322317A 2017-08-25 2018-08-24 Methods to improve organ viability Active AU2018322317B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024200468A AU2024200468A1 (en) 2017-08-25 2024-01-25 Methods to improve organ viability

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762550463P 2017-08-25 2017-08-25
US62/550,463 2017-08-25
PCT/US2018/048028 WO2019040921A1 (en) 2017-08-25 2018-08-24 METHODS OF ENHANCING VIABILITY OF AN ORGAN

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024200468A Division AU2024200468A1 (en) 2017-08-25 2024-01-25 Methods to improve organ viability

Publications (2)

Publication Number Publication Date
AU2018322317A1 AU2018322317A1 (en) 2020-03-12
AU2018322317B2 true AU2018322317B2 (en) 2023-11-23

Family

ID=65434015

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2018322317A Active AU2018322317B2 (en) 2017-08-25 2018-08-24 Methods to improve organ viability
AU2024200468A Pending AU2024200468A1 (en) 2017-08-25 2024-01-25 Methods to improve organ viability

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2024200468A Pending AU2024200468A1 (en) 2017-08-25 2024-01-25 Methods to improve organ viability

Country Status (9)

Country Link
US (4) US11044904B2 (enExample)
EP (1) EP3672403A4 (enExample)
JP (3) JP7249331B2 (enExample)
KR (2) KR102708577B1 (enExample)
CN (1) CN111107742A (enExample)
AU (2) AU2018322317B2 (enExample)
CA (1) CA3073399A1 (enExample)
MX (1) MX2020001853A (enExample)
WO (1) WO2019040921A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3030789A1 (en) 2016-07-13 2018-01-18 The Trustees Of Columbia University In The City Of New York Cross-circulation platform for recovery, regeneration, and maintenance of extracorporeal organs
AU2018322317B2 (en) * 2017-08-25 2023-11-23 Mallinckrodt Pharmaceuticals Ireland Limited Methods to improve organ viability
CN110583620A (zh) * 2019-08-26 2019-12-20 广东顺德工业设计研究院(广东顺德创新设计研究院) 离体肺脏机械灌注的调温设备及方法、装置
CN112106766B (zh) * 2020-11-18 2021-03-12 中山大学附属第一医院 一种离体心肺联合灌注系统及灌注方法
CN118142012B (zh) * 2024-03-20 2025-05-13 中国人民解放军总医院第四医学中心 离断肢体血液交叉循环系统

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7238469B2 (en) * 2001-06-21 2007-07-03 Beth Israel Deaconess Medical Center, Inc. Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis
US20170215411A1 (en) * 2013-03-15 2017-08-03 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
GB9908335D0 (en) * 1999-04-12 1999-06-09 Univ Cambridge Tech Methods and means for extracorporeal organ perfusion
AU2001241908A1 (en) * 2000-03-08 2001-09-17 Frederick A. Gage Kidney perfusion solution containing nitric oxide donor
US7504201B2 (en) * 2004-04-05 2009-03-17 Organ Recovery Systems Method for perfusing an organ and for isolating cells from the organ
US20060160062A1 (en) * 2005-01-14 2006-07-20 Young Lindon H Perfusion and/or preservation solution for organs
JP4935242B2 (ja) * 2006-08-24 2012-05-23 ニプロ株式会社 脂肪酸を含有するｓ−ニトロソタンパク質とその製法
WO2008063868A2 (en) 2006-11-07 2008-05-29 The General Hospital Corporation Attenuation of vasoactive oxygen carrier-induced vasoconstriction
JP2010530001A (ja) 2007-06-15 2010-09-02 イカリア， インコーポレイテッド 硫化物単独または一酸化窒素との組み合わせを含む組成物およびその使用
AU2011336358B2 (en) 2010-12-03 2016-09-29 VERO Biotech LLC. Nitric oxide treatments
JP2019505569A (ja) 2015-12-10 2019-02-28 ベロ バイオテック エルエルシー 血漿遊離ヘモグロビンを除去するための方法及び装置
DE102017204681A1 (de) 2017-03-21 2018-09-27 Robert Bosch Gmbh Vorrichtung zum Auslösen einer externen Schutzfunktion
AU2018322317B2 (en) * 2017-08-25 2023-11-23 Mallinckrodt Pharmaceuticals Ireland Limited Methods to improve organ viability

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7238469B2 (en) * 2001-06-21 2007-07-03 Beth Israel Deaconess Medical Center, Inc. Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis
US20170215411A1 (en) * 2013-03-15 2017-08-03 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids

Also Published As

Publication number Publication date
EP3672403A4 (en) 2021-05-19
JP7249331B2 (ja) 2023-03-30
KR20240142604A (ko) 2024-09-30
JP2020531529A (ja) 2020-11-05
AU2018322317A1 (en) 2020-03-12
KR102708577B1 (ko) 2024-09-24
AU2024200468A1 (en) 2024-02-15
US12285008B2 (en) 2025-04-29
CA3073399A1 (en) 2019-02-28
US20190059359A1 (en) 2019-02-28
US11950590B2 (en) 2024-04-09
US20240138399A1 (en) 2024-05-02
US20250228235A1 (en) 2025-07-17
US20210321605A1 (en) 2021-10-21
JP2022140622A (ja) 2022-09-26
MX2020001853A (es) 2020-08-03
US11044904B2 (en) 2021-06-29
EP3672403A1 (en) 2020-07-01
CN111107742A (zh) 2020-05-05
KR20200041359A (ko) 2020-04-21
WO2019040921A1 (en) 2019-02-28
JP2024159817A (ja) 2024-11-08

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED

Free format text: FORMER APPLICANT(S): MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED

FGA Letters patent sealed or granted (standard patent)