AU2018236651B2 - Liquid formulation of anti-TNF alpha antibody - Google Patents
Liquid formulation of anti-TNF alpha antibody Download PDFInfo
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- AU2018236651B2 AU2018236651B2 AU2018236651A AU2018236651A AU2018236651B2 AU 2018236651 B2 AU2018236651 B2 AU 2018236651B2 AU 2018236651 A AU2018236651 A AU 2018236651A AU 2018236651 A AU2018236651 A AU 2018236651A AU 2018236651 B2 AU2018236651 B2 AU 2018236651B2
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- Prior art keywords
- formulation
- adalimumab
- arginine
- formulations
- liquid formulation
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Classifications
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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Landscapes
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Applications Claiming Priority (3)
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| KR10-2017-0033188 | 2017-03-16 | ||
| KR20170033188 | 2017-03-16 | ||
| PCT/KR2018/003097 WO2018169348A1 (fr) | 2017-03-16 | 2018-03-16 | Formulation liquide d'anticorps anti-tnf alpha |
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| AU2018236651A1 AU2018236651A1 (en) | 2019-10-31 |
| AU2018236651B2 true AU2018236651B2 (en) | 2020-12-10 |
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| KR (2) | KR20180106974A (fr) |
| CN (1) | CN110621303A (fr) |
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| CO (1) | CO2019010860A2 (fr) |
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| UA (1) | UA123847C2 (fr) |
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| BR112021015034A2 (pt) | 2019-02-18 | 2021-10-05 | Eli Lilly And Company | Formulação de anticorpo terapêutico |
| TW202102260A (zh) * | 2019-03-21 | 2021-01-16 | 美商再生元醫藥公司 | 含有抗ｉｌ－３３抗體之穩定調配物 |
| US20230173068A1 (en) * | 2020-02-20 | 2023-06-08 | Bio-Thera Solutions, Ltd. | ANTI-TNF-a ANTIBODY FORMULATION, PREPARATION METHOD THEREFOR AND USE THEREOF |
Citations (2)
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| WO2015151115A1 (fr) * | 2014-04-02 | 2015-10-08 | Intas Pharmaceuticals Limited | Composition pharmaceutique liquide d'adalimumab |
| WO2016066688A1 (fr) * | 2014-10-28 | 2016-05-06 | Richter Gedeon Nyrt. | Formulation pharmaceutique d'anticorps anti-tnf-alpha |
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| US20140186361A1 (en) * | 2012-09-07 | 2014-07-03 | Coherus Biosciences, Inc. | Stable Aqueous Formulations of Adalimumab |
| CN103458926B (zh) * | 2010-11-11 | 2016-10-26 | 艾伯维生物技术有限公司 | 改进的高浓度抗TNF α 抗体液体制剂 |
| UY34105A (es) * | 2011-06-03 | 2012-07-31 | Lg Life Sciences Ltd | Formulación líquida estable de etanercept |
| SG10201609982PA (en) * | 2012-03-07 | 2017-01-27 | Cadila Healthcare Ltd | Pharmaceutical formulations of tnf-alpha anitbodies |
| EP2948473A1 (fr) * | 2013-01-24 | 2015-12-02 | GlaxoSmithKline Intellectual Property Development Limited | Protéines de liaison à l'antigène tnf-alpha |
| AR095496A1 (es) * | 2013-03-15 | 2015-10-21 | Bayer Healthcare Llc | Formulaciones de anticuerpos anti-receptor de prolactina |
| US20150274819A1 (en) * | 2014-03-03 | 2015-10-01 | La Jolla Biologics, Inc. | Stable aqueous recombinant protein formulations |
| EP3050557A1 (fr) * | 2014-05-23 | 2016-08-03 | Ares Trading S.A. | Composition pharmaceutique liquide |
| US9821059B2 (en) * | 2014-10-17 | 2017-11-21 | Alteogen Inc. | Composition for stabilizing protein and pharmaceutical formulation comprising the same |
| US20180016333A1 (en) * | 2015-01-28 | 2018-01-18 | Mabxience, S.A. | Pharmaceutical formulations for anti-tnf-alpha antibodies |
| WO2016162819A1 (fr) * | 2015-04-07 | 2016-10-13 | Lupin Limited | Composition pharmaceutique aqueuse stable d'anticorps anti-tnf alpha |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015151115A1 (fr) * | 2014-04-02 | 2015-10-08 | Intas Pharmaceuticals Limited | Composition pharmaceutique liquide d'adalimumab |
| WO2016066688A1 (fr) * | 2014-10-28 | 2016-05-06 | Richter Gedeon Nyrt. | Formulation pharmaceutique d'anticorps anti-tnf-alpha |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020510079A (ja) | 2020-04-02 |
| MY197202A (en) | 2023-05-31 |
| JP2022097600A (ja) | 2022-06-30 |
| RU2019130728A3 (fr) | 2021-04-16 |
| KR20200096472A (ko) | 2020-08-12 |
| JP7109849B2 (ja) | 2022-08-01 |
| WO2018169348A1 (fr) | 2018-09-20 |
| CO2019010860A2 (es) | 2020-01-17 |
| AU2018236651A1 (en) | 2019-10-31 |
| UA123847C2 (uk) | 2021-06-09 |
| KR20180106974A (ko) | 2018-10-01 |
| PH12019502075A1 (en) | 2020-09-14 |
| MA46988A1 (fr) | 2020-06-30 |
| RU2756619C2 (ru) | 2021-10-04 |
| NZ757965A (en) | 2022-07-01 |
| MX2019010895A (es) | 2019-11-05 |
| KR102342292B1 (ko) | 2021-12-24 |
| ZA201906696B (en) | 2020-08-26 |
| BR112019019162A2 (pt) | 2020-04-14 |
| RU2019130728A (ru) | 2021-04-16 |
| CN110621303A (zh) | 2019-12-27 |
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