AU2018235021B2 - Detection, quantification and/or isolation of circulating tumor cells based on the expression of CD321 marker - Google Patents

Detection, quantification and/or isolation of circulating tumor cells based on the expression of CD321 marker Download PDF

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Publication number
AU2018235021B2
AU2018235021B2 AU2018235021A AU2018235021A AU2018235021B2 AU 2018235021 B2 AU2018235021 B2 AU 2018235021B2 AU 2018235021 A AU2018235021 A AU 2018235021A AU 2018235021 A AU2018235021 A AU 2018235021A AU 2018235021 B2 AU2018235021 B2 AU 2018235021B2
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cells
marker
subject
cell
ctcs
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AU2018235021A1 (en
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Cédric BLANPAIN
Ievgenia PASTUSHENKO
Panagiota SOTIROPOULOU
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Universite Libre de Bruxelles ULB
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Universite Libre de Bruxelles ULB
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589—CD45
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/54—Determining the risk of relapse

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2018235021A 2017-03-16 2018-03-16 Detection, quantification and/or isolation of circulating tumor cells based on the expression of CD321 marker Active AU2018235021B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17161411.8 2017-03-16
EP17161411 2017-03-16
PCT/EP2018/056760 WO2018167312A1 (en) 2017-03-16 2018-03-16 Detection, quantification and/or isolation of circulating tumor cells based on the expression of cd321 marker

Publications (2)

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AU2018235021A1 AU2018235021A1 (en) 2019-09-12
AU2018235021B2 true AU2018235021B2 (en) 2024-07-11

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AU2018235021A Active AU2018235021B2 (en) 2017-03-16 2018-03-16 Detection, quantification and/or isolation of circulating tumor cells based on the expression of CD321 marker

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US (2) US12123877B2 (enExample)
EP (2) EP4235179B1 (enExample)
JP (1) JP7278595B2 (enExample)
KR (1) KR102583603B1 (enExample)
AU (1) AU2018235021B2 (enExample)
CA (1) CA3054915A1 (enExample)
IL (1) IL269315B2 (enExample)
WO (1) WO2018167312A1 (enExample)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
DE102019202788A1 (de) 2019-03-01 2020-09-03 Robert Bosch Gmbh Verfahren zum Zählen von Zelltypen oder Zellmarkern in einer Probe, insbesondere in einer Blutprobe
JP2020144054A (ja) * 2019-03-07 2020-09-10 学校法人昭和大学 末梢血循環癌細胞の検出方法及び検出装置
KR102654518B1 (ko) * 2020-05-26 2024-04-04 가톨릭대학교 산학협력단 Lsp1 결핍 t 세포
CN113009135B (zh) * 2021-02-19 2024-04-02 山东省大健康精准医疗产业技术研究院 一种检测cd47的管式磁微粒化学发光免疫定量试剂盒及其制备方法与应用
EP4405507A4 (en) * 2021-09-20 2025-11-05 Droplet Biosciences Inc METHODS FOR DISEASE ASSESSMENT USING A DRAINAGE FLUID

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130737A1 (en) * 2005-06-02 2006-12-07 Immunivest Corporation A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
WO2013148450A1 (en) * 2012-03-30 2013-10-03 The Board Of Trustees Of The Leland Stanford Junior University Use of jam-a in diagnosing and treating leukemia
WO2014120265A1 (en) * 2013-02-02 2014-08-07 Duke University Method of isolating circulating tumor cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US8980568B2 (en) * 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
CN104531529A (zh) * 2003-10-31 2015-04-22 维特克公司 用于检测循环肿瘤和内皮细胞的血液测试样机和方法
CA2628390A1 (en) * 2005-11-02 2007-05-18 The Regents Of The University Of Michigan Molecular profiling of cancer
CA2572530A1 (en) 2005-12-30 2007-06-30 Centocor, Inc. A method for determining the phenotype of cells
GB0808413D0 (en) 2008-05-09 2008-06-18 Univ Nottingham Stabilisation of blood cell conjugates
WO2010037134A2 (en) * 2008-09-29 2010-04-01 Stemlifeline, Inc. Multi-stage stem cell carcinogenesis
EP2199798A1 (en) 2008-12-18 2010-06-23 Universite Libre De Bruxelles Diagnostic method and kit of circulating tumor cells
EP2455403A1 (en) 2010-11-23 2012-05-23 Pierre Fabre Medicament Homogeneous humanized antibodies against JAM-A that inhibit proliferation
JP6599334B2 (ja) 2013-12-20 2019-10-30 ザ ジェネラル ホスピタル コーポレイション 血中循環腫瘍細胞に関する方法およびアッセイ
JP6693966B2 (ja) 2015-01-21 2020-05-13 エージェンシー フォー サイエンス， テクノロジー アンド リサーチ サイズに基づいて希少細胞を回収するためのカラムベースのデバイスおよび方法ならびにその使用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130737A1 (en) * 2005-06-02 2006-12-07 Immunivest Corporation A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
WO2013148450A1 (en) * 2012-03-30 2013-10-03 The Board Of Trustees Of The Leland Stanford Junior University Use of jam-a in diagnosing and treating leukemia
WO2014120265A1 (en) * 2013-02-02 2014-08-07 Duke University Method of isolating circulating tumor cells

Also Published As

Publication number Publication date
AU2018235021A1 (en) 2019-09-12
US20210190787A1 (en) 2021-06-24
EP3596467B1 (en) 2023-09-27
EP4235179A2 (en) 2023-08-30
IL269315B2 (en) 2025-05-01
IL269315A (en) 2019-11-28
KR102583603B1 (ko) 2023-10-05
EP3596467C0 (en) 2023-09-27
JP2020512549A (ja) 2020-04-23
CA3054915A1 (en) 2018-09-20
IL269315B1 (en) 2025-01-01
KR20190142330A (ko) 2019-12-26
EP4235179C0 (en) 2025-08-13
US20250027946A1 (en) 2025-01-23
EP3596467A1 (en) 2020-01-22
EP4235179B1 (en) 2025-08-13
EP4235179A3 (en) 2023-11-15
JP7278595B2 (ja) 2023-05-22
WO2018167312A1 (en) 2018-09-20
US12123877B2 (en) 2024-10-22

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