JP7278595B2 - Ｃｄ３２１マーカーの発現に基づく循環腫瘍細胞の検出、定量化、及び／又は単離 - Google Patents

Ｃｄ３２１マーカーの発現に基づく循環腫瘍細胞の検出、定量化、及び／又は単離 Download PDF

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JP7278595B2
JP7278595B2 JP2019551363A JP2019551363A JP7278595B2 JP 7278595 B2 JP7278595 B2 JP 7278595B2 JP 2019551363 A JP2019551363 A JP 2019551363A JP 2019551363 A JP2019551363 A JP 2019551363A JP 7278595 B2 JP7278595 B2 JP 7278595B2
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ブランパン，セドリック
ソティロポウロウ，パナギオタ
パシュシェンコ，エヴゲーニア
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ユニベルシテ リブレ デ ブリュッセル
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589—CD45
    • G—PHYSICS
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/54—Determining the risk of relapse

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  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2019551363A 2017-03-16 2018-03-16 Ｃｄ３２１マーカーの発現に基づく循環腫瘍細胞の検出、定量化、及び／又は単離 Active JP7278595B2 (ja)

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EP17161411.8 2017-03-16
EP17161411 2017-03-16
PCT/EP2018/056760 WO2018167312A1 (en) 2017-03-16 2018-03-16 Detection, quantification and/or isolation of circulating tumor cells based on the expression of cd321 marker

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JP2020512549A JP2020512549A (ja) 2020-04-23
JP2020512549A5 JP2020512549A5 (enExample) 2021-04-08
JP7278595B2 true JP7278595B2 (ja) 2023-05-22

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KR (1) KR102583603B1 (enExample)
AU (1) AU2018235021B2 (enExample)
CA (1) CA3054915A1 (enExample)
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DE102019202788A1 (de) * 2019-03-01 2020-09-03 Robert Bosch Gmbh Verfahren zum Zählen von Zelltypen oder Zellmarkern in einer Probe, insbesondere in einer Blutprobe
JP2020144054A (ja) * 2019-03-07 2020-09-10 学校法人昭和大学 末梢血循環癌細胞の検出方法及び検出装置
KR102654518B1 (ko) * 2020-05-26 2024-04-04 가톨릭대학교 산학협력단 Lsp1 결핍 t 세포
CN113009135B (zh) * 2021-02-19 2024-04-02 山东省大健康精准医疗产业技术研究院 一种检测cd47的管式磁微粒化学发光免疫定量试剂盒及其制备方法与应用
CA3233047A1 (en) * 2021-09-20 2023-03-23 Droplet Biosciences, Inc. Methods for disease assessment using drain fluid

Citations (5)

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JP2007526761A (ja) 2003-10-31 2007-09-20 ヴィタテックス， インコーポレイテッド 循環性の腫瘍細胞および内皮細胞の検出のための血液試験のプロトタイプおよび方法
US20100162416A1 (en) 2008-09-29 2010-06-24 Stemlifeline, Inc. Multi-stage stem cell carcinogenesis
US20110059475A1 (en) 2008-05-09 2011-03-10 The University Of Nottingham Stabilisation of blood cell conjugates
WO2015095527A1 (en) 2013-12-20 2015-06-25 The General Hosptial Corporation Methods and assays relating to circulating tumor cells
WO2016118086A1 (en) 2015-01-21 2016-07-28 Agency For Science, Technology And Research Column-based device and method for retrieval of rare cells based on size, and uses thereof

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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US8980568B2 (en) * 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
WO2006130737A1 (en) 2005-06-02 2006-12-07 Immunivest Corporation A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
WO2007056049A2 (en) 2005-11-02 2007-05-18 The Regents Of The University Of Michigan Molecular profiling of cancer
JP2007181462A (ja) 2005-12-30 2007-07-19 Centocor Inc 細胞の表現型を測定する方法
EP2199798A1 (en) 2008-12-18 2010-06-23 Universite Libre De Bruxelles Diagnostic method and kit of circulating tumor cells
EP2455403A1 (en) 2010-11-23 2012-05-23 Pierre Fabre Medicament Homogeneous humanized antibodies against JAM-A that inhibit proliferation
US20130287790A1 (en) 2012-03-30 2013-10-31 The Board Of Trustees Of The Leland Standford Junior University Use of jam-a in diagnosing and treating leukemia
CN105102978B (zh) * 2013-02-02 2018-11-02 杜克大学 分离循环肿瘤细胞的方法

Patent Citations (6)

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Publication number Priority date Publication date Assignee Title
JP2007526761A (ja) 2003-10-31 2007-09-20 ヴィタテックス， インコーポレイテッド 循環性の腫瘍細胞および内皮細胞の検出のための血液試験のプロトタイプおよび方法
US20110059475A1 (en) 2008-05-09 2011-03-10 The University Of Nottingham Stabilisation of blood cell conjugates
US20100162416A1 (en) 2008-09-29 2010-06-24 Stemlifeline, Inc. Multi-stage stem cell carcinogenesis
WO2015095527A1 (en) 2013-12-20 2015-06-25 The General Hosptial Corporation Methods and assays relating to circulating tumor cells
JP2017503488A (ja) 2013-12-20 2017-02-02 ザ ジェネラル ホスピタル コーポレイション 血中循環腫瘍細胞に関する方法およびアッセイ
WO2016118086A1 (en) 2015-01-21 2016-07-28 Agency For Science, Technology And Research Column-based device and method for retrieval of rare cells based on size, and uses thereof

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KR20190142330A (ko) 2019-12-26
EP4235179B1 (en) 2025-08-13
JP2020512549A (ja) 2020-04-23
AU2018235021B2 (en) 2024-07-11
CA3054915A1 (en) 2018-09-20
EP4235179C0 (en) 2025-08-13
EP4235179A2 (en) 2023-08-30
EP3596467B1 (en) 2023-09-27
IL269315A (en) 2019-11-28
EP4235179A3 (en) 2023-11-15
IL269315B2 (en) 2025-05-01
US12123877B2 (en) 2024-10-22
US20250027946A1 (en) 2025-01-23
KR102583603B1 (ko) 2023-10-05
WO2018167312A1 (en) 2018-09-20
EP3596467C0 (en) 2023-09-27
EP3596467A1 (en) 2020-01-22
US20210190787A1 (en) 2021-06-24
IL269315B1 (en) 2025-01-01
AU2018235021A1 (en) 2019-09-12

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