AU2017313828B2 - Compositions and methods for cancer immunotherapy - Google Patents

Compositions and methods for cancer immunotherapy Download PDF

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Publication number
AU2017313828B2
AU2017313828B2 AU2017313828A AU2017313828A AU2017313828B2 AU 2017313828 B2 AU2017313828 B2 AU 2017313828B2 AU 2017313828 A AU2017313828 A AU 2017313828A AU 2017313828 A AU2017313828 A AU 2017313828A AU 2017313828 B2 AU2017313828 B2 AU 2017313828B2
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cells
cancer
cell
cytotoxic immune
immune cells
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AU2017313828A1 (en
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William Ho
Lawrence S. Lamb
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UAB Research Foundation
IN8bio Inc
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UAB Research Foundation
IN8bio Inc
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
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    • C07K2319/00—Fusion polypeptide
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AU2017313828A 2016-08-18 2017-08-18 Compositions and methods for cancer immunotherapy Active AU2017313828B2 (en)

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US201662376680P 2016-08-18 2016-08-18
US62/376,680 2016-08-18
PCT/US2017/047515 WO2018035413A1 (en) 2016-08-18 2017-08-18 Compositions and methods for cancer immunotherapy

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AU2017313828B2 true AU2017313828B2 (en) 2019-12-05

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US (4) US20210205361A1 (https=)
EP (2) EP3500262A4 (https=)
JP (2) JP7239463B2 (https=)
KR (1) KR102659468B1 (https=)
CN (1) CN110099687A (https=)
AU (1) AU2017313828B2 (https=)
CA (1) CA3033876A1 (https=)
ES (1) ES2983739T3 (https=)
SG (1) SG11201901347UA (https=)
WO (1) WO2018035413A1 (https=)

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EP2496244B8 (en) 2009-11-02 2017-11-22 Emory University Drug resistant immunotherapy for treatment of a cancer
CN115137752A (zh) * 2015-08-25 2022-10-04 Uab研究基金会 用于干细胞移植的方法
WO2018106862A1 (en) 2016-12-07 2018-06-14 Agenus Inc. Anti-ctla-4 antibodies and methods of use thereof
CN112585166A (zh) 2018-06-23 2021-03-30 豪夫迈·罗氏有限公司 用pd-1轴结合拮抗剂、铂剂和拓扑异构酶ii抑制剂治疗肺癌的方法
CA3118696A1 (en) * 2018-11-08 2020-05-14 The Uab Research Foundation Compositions and methods for treating cancer
CN110511906A (zh) * 2019-05-16 2019-11-29 安徽瑞达健康产业有限公司 一种细胞组合物在癌细胞smmc-7721上的应用
WO2021245095A1 (en) * 2020-06-02 2021-12-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Method to improve immunotherapies
EP4281082A4 (en) 2021-01-21 2024-12-18 National Taiwan University METHOD OF TREATMENT OF CANCER
CN113476609A (zh) * 2021-08-05 2021-10-08 南京医科大学 一种替莫唑胺与次黄嘌呤-鸟嘌呤磷酸核苷转移酶小分子抑制剂组合物及其应用
WO2023021113A1 (en) * 2021-08-18 2023-02-23 Julius-Maximilians-Universität Würzburg Hybrid tumor/cancer therapy based on targeting the resolution of or inducing transcription-replication conflicts (trcs)
CN117264906A (zh) * 2023-09-18 2023-12-22 北京大学第三医院（北京大学第三临床医学院） 一种靶向PD-L1的γδT细胞及其制备方法与应用

Citations (2)

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WO2011053750A2 (en) * 2009-11-02 2011-05-05 Emory University Drug resistant immunotherapy for treatment of a cancer
WO2015142675A2 (en) * 2014-03-15 2015-09-24 Novartis Ag Treatment of cancer using chimeric antigen receptor

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