AU2017288465B2 - Two-component composition - Google Patents

Two-component composition Download PDF

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Publication number
AU2017288465B2
AU2017288465B2 AU2017288465A AU2017288465A AU2017288465B2 AU 2017288465 B2 AU2017288465 B2 AU 2017288465B2 AU 2017288465 A AU2017288465 A AU 2017288465A AU 2017288465 A AU2017288465 A AU 2017288465A AU 2017288465 B2 AU2017288465 B2 AU 2017288465B2
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AU
Australia
Prior art keywords
acid
component
aqueous solution
asa
salt
Prior art date
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AU2017288465A
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AU2017288465A1 (en
Inventor
John Bjørn FREDRIKSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asamedic AS
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Asamedic AS
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
AU2017288465A 2016-06-28 2017-06-28 Two-component composition Active AU2017288465B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20161073 2016-06-28
NO20161073 2016-06-28
PCT/EP2017/065970 WO2018002124A1 (en) 2016-06-28 2017-06-28 Two-component composition

Publications (2)

Publication Number Publication Date
AU2017288465A1 AU2017288465A1 (en) 2019-01-17
AU2017288465B2 true AU2017288465B2 (en) 2019-10-10

Family

ID=59285173

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017288465A Active AU2017288465B2 (en) 2016-06-28 2017-06-28 Two-component composition

Country Status (25)

Country Link
US (3) US11918554B2 (cg-RX-API-DMAC10.html)
EP (2) EP3871677A1 (cg-RX-API-DMAC10.html)
JP (2) JP2019520377A (cg-RX-API-DMAC10.html)
KR (1) KR102397334B1 (cg-RX-API-DMAC10.html)
CN (2) CN109789152A (cg-RX-API-DMAC10.html)
AU (1) AU2017288465B2 (cg-RX-API-DMAC10.html)
BR (1) BR112018076553A2 (cg-RX-API-DMAC10.html)
CA (1) CA3027462A1 (cg-RX-API-DMAC10.html)
CY (1) CY1124724T1 (cg-RX-API-DMAC10.html)
DK (1) DK3474858T3 (cg-RX-API-DMAC10.html)
EA (1) EA201990093A1 (cg-RX-API-DMAC10.html)
ES (1) ES2897981T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20211761T1 (cg-RX-API-DMAC10.html)
HU (1) HUE056659T2 (cg-RX-API-DMAC10.html)
IL (1) IL263982B (cg-RX-API-DMAC10.html)
LT (1) LT3474858T (cg-RX-API-DMAC10.html)
MX (1) MX388400B (cg-RX-API-DMAC10.html)
MY (1) MY195384A (cg-RX-API-DMAC10.html)
NZ (1) NZ749230A (cg-RX-API-DMAC10.html)
PL (1) PL3474858T3 (cg-RX-API-DMAC10.html)
PT (1) PT3474858T (cg-RX-API-DMAC10.html)
RS (1) RS62574B1 (cg-RX-API-DMAC10.html)
SI (1) SI3474858T1 (cg-RX-API-DMAC10.html)
SM (1) SMT202100645T1 (cg-RX-API-DMAC10.html)
WO (1) WO2018002124A1 (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3474858T (lt) 2016-06-28 2021-12-27 Asamedic As Dviejų komponentų kompozicija, apimanti acetilsalicilo rūgštį
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt
EP3501523A1 (en) * 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt
WO2020150460A1 (en) * 2019-01-18 2020-07-23 Milne Iii Donald A Micronized aspirin formulation

Citations (4)

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GB912894A (en) * 1959-11-02 1962-12-12 Guy Leopold Van Moorleghem Method for the preparing a solution of aspirin for injection and product obtained thereby
US5157030A (en) * 1989-08-25 1992-10-20 Alexander Galat Rapidly soluble aspirin compositions and method
WO2002009666A1 (en) * 2000-07-27 2002-02-07 The Boots Company Plc Pharmaceutical extemporary compositions
WO2017001468A1 (en) * 2015-07-02 2017-01-05 Asamedic As Two-component composition

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HRP20181462T1 (hr) * 2012-09-25 2018-11-02 Bayer Pharma Aktiengesellschaft Kombinacija regorafeniba i acetilsalicilne kiseline za liječenje raka debelog crijeva
SI3060203T1 (en) 2013-10-23 2018-01-31 Bayer Healthcare Llc A effervescent tablet containing a high level of aspirin
EP2777802B1 (en) 2013-12-03 2016-03-16 Capsugel Belgium NV Multi-compartment dosage form articles
LT3474858T (lt) 2016-06-28 2021-12-27 Asamedic As Dviejų komponentų kompozicija, apimanti acetilsalicilo rūgštį
EP3501523A1 (en) 2017-12-22 2019-06-26 Asamedic AS Two-component compositions comprising acetyl salicylic acid and a carbonate salt
EP3501522A1 (en) 2017-12-22 2019-06-26 Asamedic AS Compositions comprising acetylsalicylic acid and a phosphate salt

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912894A (en) * 1959-11-02 1962-12-12 Guy Leopold Van Moorleghem Method for the preparing a solution of aspirin for injection and product obtained thereby
US5157030A (en) * 1989-08-25 1992-10-20 Alexander Galat Rapidly soluble aspirin compositions and method
WO2002009666A1 (en) * 2000-07-27 2002-02-07 The Boots Company Plc Pharmaceutical extemporary compositions
WO2017001468A1 (en) * 2015-07-02 2017-01-05 Asamedic As Two-component composition

Also Published As

Publication number Publication date
IL263982A (en) 2019-01-31
CY1124724T1 (el) 2022-07-22
MX2018015965A (es) 2019-05-22
NZ749230A (en) 2023-05-26
US20210212976A1 (en) 2021-07-15
MX388400B (es) 2025-03-20
EP3871677A1 (en) 2021-09-01
RS62574B1 (sr) 2021-12-31
DK3474858T3 (da) 2021-11-22
US20240216318A1 (en) 2024-07-04
LT3474858T (lt) 2021-12-27
US11918554B2 (en) 2024-03-05
CA3027462A1 (en) 2018-01-04
SI3474858T1 (sl) 2022-01-31
US20220218724A1 (en) 2022-07-14
PL3474858T3 (pl) 2022-01-17
SMT202100645T1 (it) 2022-01-10
KR102397334B1 (ko) 2022-05-11
JP2023027071A (ja) 2023-03-01
ES2897981T3 (es) 2022-03-03
EA201990093A1 (ru) 2019-07-31
US11369581B2 (en) 2022-06-28
MY195384A (en) 2023-01-18
JP2019520377A (ja) 2019-07-18
HUE056659T2 (hu) 2022-03-28
EP3474858B1 (en) 2021-08-18
JP7520941B2 (ja) 2024-07-23
PT3474858T (pt) 2021-11-22
WO2018002124A1 (en) 2018-01-04
CN109789152A (zh) 2019-05-21
KR20190040184A (ko) 2019-04-17
AU2017288465A1 (en) 2019-01-17
EP3474858A1 (en) 2019-05-01
IL263982B (en) 2022-03-01
CN117982446A (zh) 2024-05-07
HRP20211761T1 (hr) 2022-02-18
BR112018076553A2 (pt) 2019-04-02

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