AU2017261371B2 - Method of treating lower tract urothelial cancer - Google Patents

Method of treating lower tract urothelial cancer Download PDF

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Publication number
AU2017261371B2
AU2017261371B2 AU2017261371A AU2017261371A AU2017261371B2 AU 2017261371 B2 AU2017261371 B2 AU 2017261371B2 AU 2017261371 A AU2017261371 A AU 2017261371A AU 2017261371 A AU2017261371 A AU 2017261371A AU 2017261371 B2 AU2017261371 B2 AU 2017261371B2
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Australia
Prior art keywords
gemcitabine
individual
bladder
antimetabolite
agent
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AU2017261371A
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AU2017261371A1 (en
Inventor
Vikas Agarwal
Christopher CUTIE
Dennis GIESING
Cheryl Larrivee-Elkins
Purnanand SARMA
Christopher SEARCY
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Taris Biomedical LLC
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Taris Biomedical LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AU2017261371A 2016-05-06 2017-05-05 Method of treating lower tract urothelial cancer Active AU2017261371B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662333151P 2016-05-06 2016-05-06
US62/333,151 2016-05-06
US201762443614P 2017-01-06 2017-01-06
US62/443,614 2017-01-06
PCT/US2017/031445 WO2017193098A1 (en) 2016-05-06 2017-05-05 Method of treating lower tract urothelial cancer

Publications (2)

Publication Number Publication Date
AU2017261371A1 AU2017261371A1 (en) 2018-12-13
AU2017261371B2 true AU2017261371B2 (en) 2023-07-06

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AU2017261371A Active AU2017261371B2 (en) 2016-05-06 2017-05-05 Method of treating lower tract urothelial cancer

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Country Link
US (1) US20190388338A1 (cg-RX-API-DMAC7.html)
EP (2) EP3452053B1 (cg-RX-API-DMAC7.html)
JP (3) JP7712055B2 (cg-RX-API-DMAC7.html)
KR (2) KR102435709B1 (cg-RX-API-DMAC7.html)
CN (2) CN118453872A (cg-RX-API-DMAC7.html)
AU (1) AU2017261371B2 (cg-RX-API-DMAC7.html)
CA (1) CA3023274A1 (cg-RX-API-DMAC7.html)
ES (1) ES2940227T3 (cg-RX-API-DMAC7.html)
FI (1) FI3452053T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20221544T1 (cg-RX-API-DMAC7.html)
HU (1) HUE060965T2 (cg-RX-API-DMAC7.html)
IL (2) IL295592A (cg-RX-API-DMAC7.html)
LT (1) LT3452053T (cg-RX-API-DMAC7.html)
MX (2) MX389296B (cg-RX-API-DMAC7.html)
NZ (3) NZ787786A (cg-RX-API-DMAC7.html)
PL (1) PL3452053T3 (cg-RX-API-DMAC7.html)
PT (1) PT3452053T (cg-RX-API-DMAC7.html)
RS (1) RS64032B1 (cg-RX-API-DMAC7.html)
RU (2) RU2022100624A (cg-RX-API-DMAC7.html)
SG (2) SG10201913416PA (cg-RX-API-DMAC7.html)
SI (1) SI3452053T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202300047T1 (cg-RX-API-DMAC7.html)
WO (1) WO2017193098A1 (cg-RX-API-DMAC7.html)

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PT3370768T (pt) 2015-11-03 2022-04-21 Janssen Biotech Inc Anticorpos que se ligam especificamente ao pd-1 e seus usos
TWI843168B (zh) 2016-10-11 2024-05-21 美商艾吉納斯公司 抗ｌａｇ－３抗體及其使用方法
CA3071014A1 (en) * 2017-07-25 2019-01-31 Taris Biomedical Llc Methods of treating tumor metastasis
JOP20200124A1 (ar) 2017-11-08 2020-05-20 Taris Biomedical Llc طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك
US12398209B2 (en) 2018-01-22 2025-08-26 Janssen Biotech, Inc. Methods of treating cancers with antagonistic anti-PD-1 antibodies

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WO2010151896A1 (en) 2009-06-26 2010-12-29 Taris Biomedical, Inc. Solid drug tablets for implantable drug delivery devices
EP2512581B1 (en) 2009-12-17 2021-02-17 TARIS Biomedical LLC Implantable device with intravesical tolerability
LT2600800T (lt) 2010-08-05 2021-01-11 Taris Biomedical Llc Ureteralinio stento pavidalo vaisto vartojimo įtaisas ir rinkinys
US9107816B2 (en) 2011-02-04 2015-08-18 Taris Biomedical Llc Implantable device for controlled dissolution and diffusion of low solubility drug
CA2882575C (en) 2012-08-31 2020-05-26 Dennis GIESING Drug delivery systems and methods for treatment of prostate
WO2014138214A1 (en) 2013-03-05 2014-09-12 Taris Biomedical, Inc. Drug delivery devices and methods for controlled drug release through device orifice
CN105209012B (zh) 2013-03-15 2019-02-01 塔里斯生物医药公司 用于药物递送的药物递送装置和方法
BR112015022433B1 (pt) 2013-03-15 2022-06-21 Taris Biomedical Llc Dispositivo de liberação de droga intravesical
HRP20201421T1 (hr) 2013-08-19 2020-12-11 Taris Biomedical Llc Uređaji za davanje više jedinica lijeka
LT3113782T (lt) * 2014-03-06 2022-11-25 Taris Biomedical Llc Vaisto tiekimo sistemos ir būdai, skirti šlapimo pūslės vėžio gydymui gemcitabinu
AU2015279674B2 (en) 2014-06-26 2020-07-23 Taris Biomedical Llc Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
KR102658706B1 (ko) 2015-04-23 2024-04-17 타리스 바이오메디컬 엘엘씨 약물-투과성 성분을 구비한 약물 전달 장치 및 방법

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US20140056986A1 (en) * 2010-06-02 2014-02-27 Abraxis Bioscience, Llc Methods of treating bladder cancer
US20150216937A1 (en) * 2012-03-29 2015-08-06 Altor Bioscience Corporation Methods for treating neoplasia
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BIDNUR, S. ET AL.: "Inhibiting Immune Checkpoints for the Treatment of Bladder Cancer", BLADDER CANCER, vol. 2, no. 1, 7 January 2016 (2016-01-07), pages 15 - 25, XP055439493 *
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Also Published As

Publication number Publication date
RU2018142908A (ru) 2020-06-08
KR20190005204A (ko) 2019-01-15
WO2017193098A1 (en) 2017-11-09
NZ787824A (en) 2025-10-31
BR112018072551A2 (pt) 2019-02-19
EP3452053B1 (en) 2022-12-14
RS64032B1 (sr) 2023-04-28
RU2022100624A (ru) 2022-02-09
US20190388338A1 (en) 2019-12-26
NZ748252A (en) 2025-10-31
SI3452053T1 (sl) 2023-03-31
EP3452053A1 (en) 2019-03-13
SG11201809838VA (en) 2018-12-28
EP4209221A1 (en) 2023-07-12
CN109475571A (zh) 2019-03-15
PT3452053T (pt) 2023-03-03
KR102435709B1 (ko) 2022-08-25
HUE060965T2 (hu) 2023-04-28
MX2018013432A (es) 2019-08-12
KR20220123317A (ko) 2022-09-06
PL3452053T3 (pl) 2023-05-08
NZ787786A (en) 2025-10-31
EP3452053A4 (en) 2019-12-25
CA3023274A1 (en) 2017-11-09
MX389296B (es) 2025-03-20
IL262746B (en) 2022-09-01
SMT202300047T1 (it) 2023-03-17
LT3452053T (lt) 2023-02-10
HRP20221544T1 (hr) 2023-02-17
IL262746A (en) 2018-12-31
MX2021013461A (es) 2021-12-10
JP7712055B2 (ja) 2025-07-23
SG10201913416PA (en) 2020-03-30
AU2017261371A1 (en) 2018-12-13
RU2764747C2 (ru) 2022-01-20
RU2018142908A3 (cg-RX-API-DMAC7.html) 2020-08-31
IL295592A (en) 2022-10-01
CN118453872A (zh) 2024-08-09
ES2940227T3 (es) 2023-05-04
JP2019514970A (ja) 2019-06-06
JP2022009327A (ja) 2022-01-14
FI3452053T3 (fi) 2023-04-12
JP2024028881A (ja) 2024-03-05

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