AU2017254711B2 - Degradation of cyclin-dependent kinase 8 (CDK8) by conjugation of CDK8 inhibitors with E3 ligase ligand and methods of use - Google Patents

Degradation of cyclin-dependent kinase 8 (CDK8) by conjugation of CDK8 inhibitors with E3 ligase ligand and methods of use Download PDF

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AU2017254711B2
AU2017254711B2 AU2017254711A AU2017254711A AU2017254711B2 AU 2017254711 B2 AU2017254711 B2 AU 2017254711B2 AU 2017254711 A AU2017254711 A AU 2017254711A AU 2017254711 A AU2017254711 A AU 2017254711A AU 2017254711 B2 AU2017254711 B2 AU 2017254711B2
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cancer
alkyl
independently
bifunctional compound
disease
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AU2017254711A1 (en
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Nathanael Gray
Nicholas KWIATKOWSKI
Yanke LIANG
Calla M. OLSON
Tinghu Zhang
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Dana Farber Cancer Institute Inc
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AU2017254711A 2016-04-22 2017-04-21 Degradation of cyclin-dependent kinase 8 (CDK8) by conjugation of CDK8 inhibitors with E3 ligase ligand and methods of use Active AU2017254711B2 (en)

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US201662326584P 2016-04-22 2016-04-22
US62/326,584 2016-04-22
PCT/US2017/028948 WO2017185034A1 (en) 2016-04-22 2017-04-21 Degradation of cyclin-dependent kinase 8 (cdk8) by conjugation of cdk8 inhibitors with e3 ligase ligand and methods of use

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AU2017254711A1 AU2017254711A1 (en) 2018-10-11
AU2017254711B2 true AU2017254711B2 (en) 2021-01-21

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US (3) US10865205B2 (enExample)
EP (2) EP3445764B1 (enExample)
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