AU2017214733B2 - Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53 - Google Patents

Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53 Download PDF

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Publication number
AU2017214733B2
AU2017214733B2 AU2017214733A AU2017214733A AU2017214733B2 AU 2017214733 B2 AU2017214733 B2 AU 2017214733B2 AU 2017214733 A AU2017214733 A AU 2017214733A AU 2017214733 A AU2017214733 A AU 2017214733A AU 2017214733 B2 AU2017214733 B2 AU 2017214733B2
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AU
Australia
Prior art keywords
arg
peptide
pro
prt
artificial sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2017214733A
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English (en)
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AU2017214733A1 (en
Inventor
Avi Ben-Shimon
Shay EIZENBERGER
Moshe Oren
Varda Rotter
Perry Tal
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Yeda Research and Development Co Ltd
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Yeda Research and Development Co Ltd
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Publication of AU2017214733A1 publication Critical patent/AU2017214733A1/en
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Publication of AU2017214733B2 publication Critical patent/AU2017214733B2/en
Ceased legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2017214733A 2016-02-04 2017-02-03 Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53 Ceased AU2017214733B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662291003P 2016-02-04 2016-02-04
US62/291,003 2016-02-04
PCT/IL2017/050132 WO2017134671A1 (en) 2016-02-04 2017-02-03 Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53

Publications (2)

Publication Number Publication Date
AU2017214733A1 AU2017214733A1 (en) 2018-09-06
AU2017214733B2 true AU2017214733B2 (en) 2022-09-29

Family

ID=58108701

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017214733A Ceased AU2017214733B2 (en) 2016-02-04 2017-02-03 Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53

Country Status (8)

Country Link
US (1) US11230578B2 (enExample)
EP (1) EP3411390A1 (enExample)
JP (2) JP7072508B2 (enExample)
CN (1) CN108884137B (enExample)
AU (1) AU2017214733B2 (enExample)
CA (1) CA3012302A1 (enExample)
RU (1) RU2762089C2 (enExample)
WO (1) WO2017134671A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016002721A2 (pt) 2013-08-07 2018-07-10 Yeda Research And Development Company Ltd. peptídeos capazes de reativar p53 mutantes
US20220251159A1 (en) * 2016-02-04 2022-08-11 Yeda Research And Development Co., Ltd Peptides and use of same in the treatment of diseases, disroders or conditions associated with a mutant p53
CA3012302A1 (en) 2016-02-04 2017-08-10 Yeda Research And Development Co. Ltd. Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53
EP4121441A1 (en) * 2020-03-16 2023-01-25 Yeda Research and Development Co. Ltd Peptide analogs and use of same in treating diseases, disorders or conditions associated with a mutant p53 protein
CN112578106B (zh) * 2020-04-13 2022-04-22 南京大学 一种纳米孔道单分子蛋白质测序仪
CN112921032A (zh) * 2020-12-29 2021-06-08 苏州中科先进技术研究院有限公司 一种引物对、探针、试剂盒及其使用方法

Citations (3)

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WO1997030074A1 (en) * 1996-02-16 1997-08-21 Cytogen Corporation Isolation and use of sh3 binding peptides
WO2013036208A1 (en) * 2011-09-09 2013-03-14 Agency For Science, Technology And Research P53 activating peptides
WO2015019318A1 (en) * 2013-08-07 2015-02-12 Yeda Research And Development Co. Ltd. Peptides capable of reactivating p53 mutants

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* Cited by examiner, † Cited by third party
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WO1997030074A1 (en) * 1996-02-16 1997-08-21 Cytogen Corporation Isolation and use of sh3 binding peptides
WO2013036208A1 (en) * 2011-09-09 2013-03-14 Agency For Science, Technology And Research P53 activating peptides
WO2015019318A1 (en) * 2013-08-07 2015-02-12 Yeda Research And Development Co. Ltd. Peptides capable of reactivating p53 mutants

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Also Published As

Publication number Publication date
CN108884137B (zh) 2022-04-05
US11230578B2 (en) 2022-01-25
RU2018131120A (ru) 2020-03-05
CN108884137A (zh) 2018-11-23
WO2017134671A1 (en) 2017-08-10
JP2022112518A (ja) 2022-08-02
US20190048053A1 (en) 2019-02-14
EP3411390A1 (en) 2018-12-12
JP7072508B2 (ja) 2022-05-20
CA3012302A1 (en) 2017-08-10
JP2019512004A (ja) 2019-05-09
AU2017214733A1 (en) 2018-09-06
RU2762089C2 (ru) 2021-12-15
RU2018131120A3 (enExample) 2020-06-25

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired