AU2016355117B2 - Improvements relating to substrates for the attachment of molecules - Google Patents

Improvements relating to substrates for the attachment of molecules Download PDF

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Publication number
AU2016355117B2
AU2016355117B2 AU2016355117A AU2016355117A AU2016355117B2 AU 2016355117 B2 AU2016355117 B2 AU 2016355117B2 AU 2016355117 A AU2016355117 A AU 2016355117A AU 2016355117 A AU2016355117 A AU 2016355117A AU 2016355117 B2 AU2016355117 B2 AU 2016355117B2
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Australia
Prior art keywords
substrate
reaction zones
substrate according
discrete reaction
coating
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AU2016355117A
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AU2016355117A1 (en
Inventor
Elouard Benchikh
Peter Fitzgerald
John Lamont
Ivan McConnell
Ciaran RICHARDSON
Deepesh UPADHYAY
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Randox Laboratories Ltd
Randox Teoranta
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Randox Laboratories Ltd
Randox Teoranta
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
    • B32B3/10—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material
    • B32B3/12—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material characterised by a layer of regularly- arranged cells, e.g. a honeycomb structure
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00—Inks
    • C09D11/02—Printing inks
    • C09D11/03—Printing inks characterised by features other than the chemical nature of the binder
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00—Inks
    • C09D11/02—Printing inks
    • C09D11/10—Printing inks based on artificial resins
    • C09D11/102—Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00855—Surface features

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Materials Engineering (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Details Or Accessories Of Spraying Plant Or Apparatus (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Paints Or Removers (AREA)
AU2016355117A 2015-11-18 2016-11-18 Improvements relating to substrates for the attachment of molecules Active AU2016355117B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1520341.7 2015-11-18
GBGB1520341.7A GB201520341D0 (en) 2015-11-18 2015-11-18 Improvements relating to substrates for the attachment of molecules
PCT/GB2016/053608 WO2017085509A1 (en) 2015-11-18 2016-11-18 Improvements relating to substrates for the attachment of molecules

Publications (2)

Publication Number Publication Date
AU2016355117A1 AU2016355117A1 (en) 2018-06-07
AU2016355117B2 true AU2016355117B2 (en) 2023-05-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016355117A Active AU2016355117B2 (en) 2015-11-18 2016-11-18 Improvements relating to substrates for the attachment of molecules

Country Status (11)

Country Link
US (3) US10279332B2 (enExample)
EP (1) EP3377900B1 (enExample)
JP (1) JP6943448B2 (enExample)
KR (1) KR102613057B1 (enExample)
CN (1) CN108700578B (enExample)
AU (1) AU2016355117B2 (enExample)
BR (1) BR112018010023A2 (enExample)
CA (1) CA3005515C (enExample)
GB (1) GB201520341D0 (enExample)
RU (1) RU2742666C2 (enExample)
WO (1) WO2017085509A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201818744D0 (en) 2018-11-16 2019-01-02 Randox Laboratories Ltd Detection of bladder cancer
EP4314821A1 (en) 2021-03-31 2024-02-07 Randox Laboratories Ltd. Coronavirus assay
EP4314822A1 (en) 2021-03-31 2024-02-07 Randox Laboratories Ltd. Detection assay
GB202109635D0 (en) 2021-07-02 2021-08-18 Randox Laboratories Ltd Vision system
GB202114088D0 (en) 2021-10-01 2021-11-17 Randox Laboratories Detection of bladder cancer in males
WO2024092388A1 (zh) * 2022-10-31 2024-05-10 深圳华大智造科技股份有限公司 一种核酸加载试剂及用其检测测序芯片吸附能力的方法
GB202405974D0 (en) 2024-04-29 2024-06-12 Randox Laboratories Ltd Method of stratifying haematuria patients

Citations (3)

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WO2006023324A1 (en) * 2004-08-17 2006-03-02 Biocept, Inc. Protein microarrays
US20120035081A1 (en) * 2010-08-05 2012-02-09 Xerox Corporation Non-polar solid inks for biomedical applications
WO2013063382A2 (en) * 2011-10-28 2013-05-02 Illumina, Inc. Microarray fabrication system and method

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CZ297165B6 (cs) * 1997-04-21 2006-09-13 Randox Laboratories Ltd. A British Company Of Ardmore Zpusob výroby zarízení s pevnou fází k provádení multianalytních rozboru
EP0874242B2 (en) * 1997-04-21 2009-06-03 Randox Laboratories Ltd. Device and apparatus for the simultaneous detection of multiple analytes
CA2244414A1 (en) * 1997-08-01 1999-02-01 Canon Kabushiki Kaisha Reaction site array, preparation process of it, reaction process using it and quantitative determination method of substance in sample solution using it
JP3610231B2 (ja) * 1997-08-01 2005-01-12 キヤノン株式会社 反応場アレー、反応場アレーの製造方法、反応場アレーを用いた反応方法及び反応場アレーを用いた試料溶液中の物質の定量方法
DE19756465C1 (de) * 1997-12-18 1999-09-23 Degussa Modifizierte Ruße enthaltende Lacke und Druckfarben
US6750023B2 (en) * 1999-09-02 2004-06-15 Corning Incorporated Porous inorganic substrate for high-density arrays
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JP4378042B2 (ja) * 2000-08-31 2009-12-02 キヤノン株式会社 検体試料中の対象成分の検出方法、およびそれに用いる検出用基板
JP2003014760A (ja) * 2001-04-27 2003-01-15 Canon Inc プローブ担体、プローブ固定用担体およびそれらの製造方法
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CN103589631B (zh) * 2013-11-19 2015-04-22 苏州晶方半导体科技股份有限公司 生物芯片封装结构及其封装方法

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2006023324A1 (en) * 2004-08-17 2006-03-02 Biocept, Inc. Protein microarrays
US20120035081A1 (en) * 2010-08-05 2012-02-09 Xerox Corporation Non-polar solid inks for biomedical applications
WO2013063382A2 (en) * 2011-10-28 2013-05-02 Illumina, Inc. Microarray fabrication system and method

Also Published As

Publication number Publication date
KR20180115257A (ko) 2018-10-22
AU2016355117A1 (en) 2018-06-07
RU2018118166A3 (enExample) 2020-03-18
KR102613057B1 (ko) 2023-12-11
RU2742666C2 (ru) 2021-02-09
RU2018118166A (ru) 2019-12-18
US20190247820A1 (en) 2019-08-15
CA3005515A1 (en) 2017-05-26
EP3377900B1 (en) 2021-09-15
HK1254090A1 (zh) 2019-07-12
CA3005515C (en) 2023-07-04
EP3377900A1 (en) 2018-09-26
WO2017085509A1 (en) 2017-05-26
JP6943448B2 (ja) 2021-09-29
CN108700578B (zh) 2021-09-24
JP2018534577A (ja) 2018-11-22
US20190344240A1 (en) 2019-11-14
US11383216B2 (en) 2022-07-12
US20180339282A1 (en) 2018-11-29
GB201520341D0 (en) 2015-12-30
US10279332B2 (en) 2019-05-07
CN108700578A (zh) 2018-10-23
US11396003B2 (en) 2022-07-26
BR112018010023A2 (en) 2018-11-21

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