AU2016318163B2 - Genetically-engineered drug resistant T cells and methods of using the same - Google Patents

Genetically-engineered drug resistant T cells and methods of using the same Download PDF

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Publication number
AU2016318163B2
AU2016318163B2 AU2016318163A AU2016318163A AU2016318163B2 AU 2016318163 B2 AU2016318163 B2 AU 2016318163B2 AU 2016318163 A AU2016318163 A AU 2016318163A AU 2016318163 A AU2016318163 A AU 2016318163A AU 2016318163 B2 AU2016318163 B2 AU 2016318163B2
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cells
cancer
cell composition
cell
subject
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AU2016318163A1 (en
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G. Yancey Gillespie
Lawrence S. Lamb
H. Trent SPENCER
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Emory University
UAB Research Foundation
Childrens Healthcare of Atlanta Inc
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Emory University
UAB Research Foundation
Childrens Healthcare of Atlanta Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
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    • C12N5/0602—Vertebrate cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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AU2016318163A 2015-09-03 2016-09-06 Genetically-engineered drug resistant T cells and methods of using the same Active AU2016318163B2 (en)

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US201562214071P 2015-09-03 2015-09-03
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US (2) US12005078B2 (https=)
EP (3) EP4295914A3 (https=)
JP (2) JP7186615B2 (https=)
KR (1) KR20180086183A (https=)
CN (1) CN108291209A (https=)
AU (2) AU2016318163B2 (https=)
CA (1) CA2997547A1 (https=)
ES (2) ES2910709T3 (https=)
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WO (1) WO2017041106A1 (https=)

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GB201715918D0 (en) * 2017-09-29 2017-11-15 Tc Biopharm Ltd Modified CAR-T
EP3818148A4 (en) * 2018-07-05 2022-09-28 Emory University TRANSDUCTION OF CONGENITAL IMMUNE COMPETENT CELLS USING AAV6
MX2021000459A (es) * 2018-07-13 2021-06-23 Univ Kyoto Metodo para producir celulas t gamma y delta.
US20210346430A9 (en) * 2018-08-26 2021-11-11 Oaiscell Biotechnologies Method for treating glioblastoma
CA3118696A1 (en) * 2018-11-08 2020-05-14 The Uab Research Foundation Compositions and methods for treating cancer

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US12005078B2 (en) 2024-06-11
IL257763B (en) 2021-05-31
KR20180086183A (ko) 2018-07-30
JP2018526453A (ja) 2018-09-13
JP7662588B2 (ja) 2025-04-15
JP7186615B2 (ja) 2022-12-09
EP3344760B1 (en) 2022-01-12
CN108291209A (zh) 2018-07-17
EP4006146A1 (en) 2022-06-01
IL282220B (en) 2022-06-01
ES2910709T3 (es) 2022-05-13
CA2997547A1 (en) 2017-03-09
ES2965437T3 (es) 2024-04-15
AU2022235516A1 (en) 2022-10-13
IL282220A (en) 2021-05-31
EP4006146B1 (en) 2023-09-06
EP4295914A2 (en) 2023-12-27
AU2016318163A1 (en) 2018-03-29
JP2022184987A (ja) 2022-12-13
EP3344760A1 (en) 2018-07-11
WO2017041106A1 (en) 2017-03-09
IL257763A (en) 2018-04-30
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