AU2015370919A1 - Phosphopantetheine compounds alone or in combination with HMG-CoA reductase inhibitors for lowering serum cholesterol and serum triglicerides - Google Patents

Phosphopantetheine compounds alone or in combination with HMG-CoA reductase inhibitors for lowering serum cholesterol and serum triglicerides Download PDF

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Publication number
AU2015370919A1
AU2015370919A1 AU2015370919A AU2015370919A AU2015370919A1 AU 2015370919 A1 AU2015370919 A1 AU 2015370919A1 AU 2015370919 A AU2015370919 A AU 2015370919A AU 2015370919 A AU2015370919 A AU 2015370919A AU 2015370919 A1 AU2015370919 A1 AU 2015370919A1
Authority
AU
Australia
Prior art keywords
substituted
unsubstituted
alkyl
methyl
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2015370919A
Other languages
English (en)
Inventor
Stefan Fujs
Gregor Kosec
Hrvoje Petkovic
Oda Cornelia Maria Sibon
Balaji Srinivasan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rijksuniversiteit Groningen
Academisch Ziekenhuis Groningen
Acies Bio doo
Original Assignee
Rijksuniversiteit Groningen
Academisch Ziekenhuis Groningen
Acies Bio doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rijksuniversiteit Groningen, Academisch Ziekenhuis Groningen, Acies Bio doo filed Critical Rijksuniversiteit Groningen
Publication of AU2015370919A1 publication Critical patent/AU2015370919A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/345—Nitrofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2015370919A 2014-12-23 2015-12-23 Phosphopantetheine compounds alone or in combination with HMG-CoA reductase inhibitors for lowering serum cholesterol and serum triglicerides Abandoned AU2015370919A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI201400452A SI24899A (sl) 2014-12-23 2014-12-23 Fosfopanteteinske spojine,same ali v kombinaciji z inhibitorji HMG-COA reduktaze za zniževanje serumskega holesterola in serumskih trigliceridov
SIP-201400452 2014-12-23
PCT/EP2015/081184 WO2016102680A1 (en) 2014-12-23 2015-12-23 Phosphopantetheine compounds alone or in combination with hmg-coa reductase inhibitors for lowering serum cholesterol and serum triglicerides

Publications (1)

Publication Number Publication Date
AU2015370919A1 true AU2015370919A1 (en) 2017-07-06

Family

ID=55022496

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015370919A Abandoned AU2015370919A1 (en) 2014-12-23 2015-12-23 Phosphopantetheine compounds alone or in combination with HMG-CoA reductase inhibitors for lowering serum cholesterol and serum triglicerides

Country Status (7)

Country Link
US (1) US10624908B2 (sl)
EP (1) EP3236958A1 (sl)
AU (1) AU2015370919A1 (sl)
CA (1) CA2970852A1 (sl)
HK (1) HK1246155A1 (sl)
SI (1) SI24899A (sl)
WO (1) WO2016102680A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113727986A (zh) * 2018-11-30 2021-11-30 彗星医疗股份有限公司 环状泛硫醇衍生物及其用途
AU2020245580A1 (en) * 2019-03-27 2021-10-28 Comet Therapeutics, Inc. Pantethenoylcysteine derivatives and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006509722A (ja) * 2002-07-03 2006-03-23 エスペリオン セラピューティクス，インコーポレイテッド 脂質代謝異常を治療するためのパンテチン含有組成物
WO2011030727A1 (ja) * 2009-09-11 2011-03-17 第一ファインケミカル株式会社 パンテチンリン酸エステルを含む外用剤
US20140045874A1 (en) * 2012-07-09 2014-02-13 Noglo Llc Prevention of alcohol reaction with dietary supplements
EP2868662A1 (en) * 2013-11-04 2015-05-06 Acies Bio d.o.o. Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds

Also Published As

Publication number Publication date
EP3236958A1 (en) 2017-11-01
CA2970852A1 (en) 2016-06-30
HK1246155A1 (zh) 2018-09-07
WO2016102680A1 (en) 2016-06-30
US20180214461A1 (en) 2018-08-02
US10624908B2 (en) 2020-04-21
SI24899A (sl) 2016-06-30

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted