HK1246155A1 - 磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯 - Google Patents

磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯

Info

Publication number
HK1246155A1
HK1246155A1 HK18105574.3A HK18105574A HK1246155A1 HK 1246155 A1 HK1246155 A1 HK 1246155A1 HK 18105574 A HK18105574 A HK 18105574A HK 1246155 A1 HK1246155 A1 HK 1246155A1
Authority
HK
Hong Kong
Prior art keywords
serum
triglicerides
phosphopantetheine
hmg
combination
Prior art date
Application number
HK18105574.3A
Other languages
English (en)
Inventor
Gregor Kosec
Stefan Fujs
Hrvoje Petkovic
Oda Cornelia Maria Sibon
Balaji Srinivasan
Original Assignee
Acies Bio D O O
Univ Groningen
Academisch Ziekenhuis Groningen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acies Bio D O O, Univ Groningen, Academisch Ziekenhuis Groningen filed Critical Acies Bio D O O
Publication of HK1246155A1 publication Critical patent/HK1246155A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/345—Nitrofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18105574.3A 2014-12-23 2018-04-30 磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯 HK1246155A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI201400452A SI24899A (sl) 2014-12-23 2014-12-23 Fosfopanteteinske spojine,same ali v kombinaciji z inhibitorji HMG-COA reduktaze za zniževanje serumskega holesterola in serumskih trigliceridov
PCT/EP2015/081184 WO2016102680A1 (en) 2014-12-23 2015-12-23 Phosphopantetheine compounds alone or in combination with hmg-coa reductase inhibitors for lowering serum cholesterol and serum triglicerides

Publications (1)

Publication Number Publication Date
HK1246155A1 true HK1246155A1 (zh) 2018-09-07

Family

ID=55022496

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105574.3A HK1246155A1 (zh) 2014-12-23 2018-04-30 磷酸泛酰巰基乙胺化合物單獨或與hmg-coa還原酶抑制劑聯合用於降低血清胆固醇和血清三酸甘油酯

Country Status (7)

Country Link
US (1) US10624908B2 (zh)
EP (1) EP3236958A1 (zh)
AU (1) AU2015370919A1 (zh)
CA (1) CA2970852A1 (zh)
HK (1) HK1246155A1 (zh)
SI (1) SI24899A (zh)
WO (1) WO2016102680A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022511469A (ja) * 2018-11-30 2022-01-31 コメット セラピューティクス インコーポレイテッド 環状パンテテイン誘導体及びその使用
CA3131848A1 (en) * 2019-03-27 2020-10-01 Comet Therapeutics, Inc. Pantethenoylcysteine derivatives and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1519751A2 (en) * 2002-07-03 2005-04-06 Esperion Therapeutics Inc. Compositions comprising panthetine for the treatment of dyslipidemia
KR20120065371A (ko) * 2009-09-11 2012-06-20 다이이치 파인 케미칼 가부시키가이샤 판테틴인산에스테르를 함유하는 외용제
EP2869717B8 (en) * 2012-07-09 2018-07-25 NoGlo, Inc. Prevention of alcohol reaction with dietary supplements
EP2868662A1 (en) * 2013-11-04 2015-05-06 Acies Bio d.o.o. Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds

Also Published As

Publication number Publication date
EP3236958A1 (en) 2017-11-01
WO2016102680A1 (en) 2016-06-30
US20180214461A1 (en) 2018-08-02
US10624908B2 (en) 2020-04-21
SI24899A (sl) 2016-06-30
AU2015370919A1 (en) 2017-07-06
CA2970852A1 (en) 2016-06-30

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