AU2015335652B2 - Cancer and skin lesion treatment - Google Patents

Cancer and skin lesion treatment Download PDF

Info

Publication number
AU2015335652B2
AU2015335652B2 AU2015335652A AU2015335652A AU2015335652B2 AU 2015335652 B2 AU2015335652 B2 AU 2015335652B2 AU 2015335652 A AU2015335652 A AU 2015335652A AU 2015335652 A AU2015335652 A AU 2015335652A AU 2015335652 B2 AU2015335652 B2 AU 2015335652B2
Authority
AU
Australia
Prior art keywords
dose
hpv
cancer
vaccine
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2015335652A
Other languages
English (en)
Other versions
AU2015335652A1 (en
Inventor
Tim Ioannides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hpvvax LLC
Original Assignee
Hpvvax LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hpvvax LLC filed Critical Hpvvax LLC
Publication of AU2015335652A1 publication Critical patent/AU2015335652A1/en
Application granted granted Critical
Publication of AU2015335652B2 publication Critical patent/AU2015335652B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20071—Demonstrated in vivo effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2015335652A 2014-10-24 2015-10-23 Cancer and skin lesion treatment Active AU2015335652B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462068332P 2014-10-24 2014-10-24
US62/068,332 2014-10-24
PCT/US2015/057150 WO2016065281A1 (en) 2014-10-24 2015-10-23 Cancer and skin lesion treatment

Publications (2)

Publication Number Publication Date
AU2015335652A1 AU2015335652A1 (en) 2017-05-25
AU2015335652B2 true AU2015335652B2 (en) 2020-07-02

Family

ID=55761638

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015335652A Active AU2015335652B2 (en) 2014-10-24 2015-10-23 Cancer and skin lesion treatment

Country Status (15)

Country Link
US (1) US10238729B2 (https=)
EP (1) EP3209676A4 (https=)
JP (1) JP6663438B2 (https=)
KR (1) KR102285401B1 (https=)
CN (1) CN107001430A (https=)
AU (1) AU2015335652B2 (https=)
BR (1) BR112017008280A2 (https=)
CA (1) CA2965498A1 (https=)
CL (1) CL2017001008A1 (https=)
IL (1) IL251825B2 (https=)
MX (1) MX395186B (https=)
MY (1) MY195018A (https=)
PH (1) PH12017500754A1 (https=)
SG (1) SG11201703262UA (https=)
WO (1) WO2016065281A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019506435A (ja) * 2016-02-27 2019-03-07 エイチピーブイヴァックス, リミテッド ライアビリティー カンパニー.Hpvvax, Llc. ワクチンを使用して癌または皮膚病変を治療するための方法および組成物

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2284559T3 (es) * 2001-03-23 2007-11-16 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Genes y proteinas e6 y e7 modificados del vph utiles como vacuna.
GB0110431D0 (en) * 2001-04-27 2001-06-20 Glaxosmithkline Biolog Sa Novel compounds
US20060222656A1 (en) 2005-04-01 2006-10-05 University Of Maryland, Baltimore MAGE-A3/HPV 16 peptide vaccines for head and neck cancer
GB0206359D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
GB0206360D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
GB0222953D0 (en) * 2002-10-03 2002-11-13 Glaxo Group Ltd Novel Compounds
WO2004056389A1 (en) 2002-12-20 2004-07-08 Glaxosmithkline Biologicals Sa Hpv-16 and -18 l1 vlp vaccine
PE20060434A1 (es) * 2004-06-16 2006-06-08 Glaxosmithkline Biolog Sa Composicion inmunogenica que comprende plv o capsomeros de vph 16, vph 18 y al menos otro tipo de cancer de vph
GB0417430D0 (en) 2004-08-05 2004-09-08 Uc3 A novel HPV vaccine comprising peptides from host cell proteins
US8399610B2 (en) 2004-08-05 2013-03-19 University College Cardiff Consultants Limited HPV vaccine comprising peptides from host cell proteins
WO2008112125A1 (en) * 2007-03-09 2008-09-18 Merck & Co., Inc. Papillomavirus vaccine compositions
CN101530614A (zh) * 2008-03-10 2009-09-16 北京康乐卫士生物技术有限公司 五价重组人乳头瘤病毒疫苗
CN101530612A (zh) * 2008-03-10 2009-09-16 北京康乐卫士生物技术有限公司 16型重组人乳头瘤病毒疫苗
US20110110979A1 (en) 2008-04-16 2011-05-12 Universite De Lausanne Method and vaccine for optimizing the specific immune responses
WO2010118424A2 (en) * 2009-04-10 2010-10-14 The Johns Hopkins University Papillomavirus-like particles (vlp) as broad spectrum human papillomavirus (hpv) vaccines
EP3427755B1 (en) * 2009-04-13 2020-10-21 INSERM - Institut National de la Santé et de la Recherche Médicale Hpv particles and uses thereof
CN101890160B (zh) * 2009-04-28 2014-06-18 北京康乐卫士生物技术有限公司 多价重组人乳头瘤病毒疫苗及其应用
US9566323B2 (en) 2009-06-19 2017-02-14 Eyegene Inc. Vaccine for cervical cancer
SG177269A1 (en) * 2009-06-25 2012-02-28 Glaxosmithkline Biolog Sa Novel human papillomavirus (hpv) protein constructs and their use in the prevention of hpv disease
AR074485A1 (es) * 2009-12-04 2011-01-19 Consejo Nac Invest Cient Tec Vacuna contra lesiones neoplasicas o cancerosas causadas por el virus del papiloma humano (vph), procedimientos, usos y metodos
JP2014516075A (ja) * 2011-06-06 2014-07-07 シェブロン フィリップス ケミカル カンパニー エルピー 癌治療のためのメタロセン化合物の使用
US20130064849A1 (en) * 2011-07-14 2013-03-14 The Board Of Regents Of The University Of Texas Methods to treat and prevent cardiovascular disease using human papillomavirus vaccines
WO2013139744A1 (en) * 2012-03-18 2013-09-26 Glaxosmithkline Biologicals S.A. Method of vaccination against human papillomavirus
US20150086587A1 (en) * 2012-03-28 2015-03-26 Kansas State University Research Foundation Vaccine adjuvant
US20140275082A1 (en) * 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US9974849B2 (en) 2013-10-13 2018-05-22 Bioventures, Llc Human Papilloma virus therapeutic vaccine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
LANDIS M. N. et al., (2012) "Recalcitrant plantar warts treated with recombinant quadrivalent human papillomavirus vaccine", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY., vol. 67, no. 2, pages e73 - e74 *
LIU T. Y. et al., (2012) "Advances in Peptide-based Human Papillomavirus Therapeutic Vaccines", CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 12, no. 14, pages 1581 - 1592 *
Venugopal et al., "Recalcitrant cutaneous warts treated with recombinant quadrivalent human papillomavirus vaccine (Types 6, 11, 16 and 18) in a developmentally delayed, 31-year-old white man", Arch Dermatol., 2010, 146(5):475-477. *

Also Published As

Publication number Publication date
CA2965498A1 (en) 2016-04-28
PH12017500754A1 (en) 2017-10-30
KR102285401B1 (ko) 2021-08-02
JP2017531699A (ja) 2017-10-26
IL251825B1 (en) 2023-05-01
CL2017001008A1 (es) 2017-11-24
WO2016065281A1 (en) 2016-04-28
MX2017005418A (es) 2017-11-30
CN107001430A (zh) 2017-08-01
BR112017008280A2 (pt) 2018-01-02
US20160114023A1 (en) 2016-04-28
MY195018A (en) 2023-01-03
US10238729B2 (en) 2019-03-26
IL251825A0 (en) 2017-06-29
MX395186B (es) 2025-03-21
EP3209676A1 (en) 2017-08-30
KR20170072279A (ko) 2017-06-26
AU2015335652A1 (en) 2017-05-25
EP3209676A4 (en) 2018-03-28
SG11201703262UA (en) 2017-05-30
JP6663438B2 (ja) 2020-03-11
IL251825B2 (en) 2023-09-01

Similar Documents

Publication Publication Date Title
Stern et al. Therapy of human papillomavirus-related disease
Abeck et al. Quadrivalent human papillomavirus vaccination: a promising treatment for recalcitrant cutaneous warts in children
Tsai Clinical cancer chemoprevention: From the hepatitis B virus (HBV) vaccine to the human papillomavirus (HPV) vaccine
KR20040030599A (ko) Ｈｉｖ 항원 및 ｈｓｖ 항원 및/또는 ｈｐｖ 항원을포함하는 다가 백신
Ding et al. Effectiveness of combination therapy with ISA101 vaccine for the treatment of human papillomavirus-induced cervical cancer
CN105597092A (zh) 含有白介素15的防治hpv感染的疫苗喷雾剂
CA3166256A1 (en) Human papillomavirus (hpv) virus-like particles (vlps) vaccine
AU2015335652B2 (en) Cancer and skin lesion treatment
KR102873848B1 (ko) 백신을 사용하여 암 또는 피부 병변을 치료하기 위한 방법 및 조성물
Silva Filho et al. Immunization in women’s lives: present and future
CN1935262B (zh) 红色诺卡氏菌细胞壁骨架在制备抗人乳头瘤病毒药物的用途
Devadasan et al. HPV vaccines–A game changer for preventing HPV-related cancers
US20100285058A1 (en) Dna vaccine for treating or preventing cervical cancer comprising a gene encoding hpv protein
HK1241898A1 (en) Cancer and skin lesion treatment
Abdulsalam et al. Role of HPV vaccines in multiple recalcitrant warts treatment
JP2017531699A5 (https=)
US10512683B2 (en) Combination therapies for human papillomavirus-associated diseases comprising administration of therapeutic vaccine and recombinant virus vector
Al-Azmi et al. Human papillomavirus: manifestations, prevention and treatment: an overview
Fruscalzo et al. Second-generation prophylactic HPV vaccines: current options and future strategies for vaccines development
Zawadka Human papilloma virus vaccination
Solov'ev et al. Immunotherapy with isoprinosine as an adjuvant or independent method of treatment for patientswith papilloma viral infection
Jorge et al. Update: HPV prevention
Tezikov et al. Anogenital Warts: New Opportunities for Prevention
Elliott Human Papillomavirus 9-valent Vaccine, Recombinant (Gardasil® 9)
US20170165351A1 (en) Method and composition for treating cancer or skin lesion using a vaccine

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)