AU2015213721B2 - Methods for treating fibrotic disease - Google Patents

Methods for treating fibrotic disease Download PDF

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Publication number
AU2015213721B2
AU2015213721B2 AU2015213721A AU2015213721A AU2015213721B2 AU 2015213721 B2 AU2015213721 B2 AU 2015213721B2 AU 2015213721 A AU2015213721 A AU 2015213721A AU 2015213721 A AU2015213721 A AU 2015213721A AU 2015213721 B2 AU2015213721 B2 AU 2015213721B2
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Australia
Prior art keywords
modulator
genes
translational
fibrotic
myofibroblasts
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AU2015213721A
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AU2015213721A1 (en
Inventor
James Appleman
Peggy A. Thompson
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Effector Therapeutics Inc
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Effector Therapeutics Inc
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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AU2015213721A 2014-02-07 2015-02-07 Methods for treating fibrotic disease Ceased AU2015213721B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461937272P 2014-02-07 2014-02-07
US61/937,272 2014-02-07
US201462010004P 2014-06-10 2014-06-10
US62/010,004 2014-06-10
US201462037497P 2014-08-14 2014-08-14
US62/037,497 2014-08-14
PCT/US2015/014939 WO2015120350A2 (en) 2014-02-07 2015-02-07 Compositions and methods for treating fibrotic disease

Publications (2)

Publication Number Publication Date
AU2015213721A1 AU2015213721A1 (en) 2016-07-28
AU2015213721B2 true AU2015213721B2 (en) 2021-05-20

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AU2015213721A Ceased AU2015213721B2 (en) 2014-02-07 2015-02-07 Methods for treating fibrotic disease

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US (2) US9993494B2 (enExample)
EP (1) EP3102703A2 (enExample)
JP (1) JP2017510552A (enExample)
CN (1) CN106102775A (enExample)
AU (1) AU2015213721B2 (enExample)
CA (1) CA2938592A1 (enExample)
WO (1) WO2015120350A2 (enExample)

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CN107916254B (zh) * 2017-11-29 2020-05-12 武汉大学 Homer1单克隆抗体及其应用
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WO2019180664A1 (en) * 2018-03-21 2019-09-26 The University Of Hong Kong Method for preventing or modulating fibrosis and fibrotic response associated with the integrated stress response
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KR102100163B1 (ko) 2019-09-24 2020-04-13 테고사이언스 (주) 켈로이드 또는 비후성 반흔 예방 또는 치료용 조성물
CN111228464A (zh) * 2020-02-28 2020-06-05 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 广谱抗冠状病毒的多肽及其用途
CN113679841A (zh) * 2020-05-19 2021-11-23 上海市同济医院 一种磷脂酶d1(pld1)基因及其抑制剂在肝纤维化防治中的应用
CA3179187A1 (en) 2020-05-22 2021-11-25 Qx Therapeutics Inc. Compositions and methods for treating lung injuries associated with viral infections
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US20230374591A1 (en) * 2020-10-08 2023-11-23 The Trustees Of Dartmouth College Methods and agents for treating, preventing, diagnosing, and evaluating therapy for fibrotic, autoimmune, and inflammatory conditions
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