AU2014340098B2 - Micro-fluidic devices for assaying biological activity - Google Patents

Micro-fluidic devices for assaying biological activity Download PDF

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Publication number
AU2014340098B2
AU2014340098B2 AU2014340098A AU2014340098A AU2014340098B2 AU 2014340098 B2 AU2014340098 B2 AU 2014340098B2 AU 2014340098 A AU2014340098 A AU 2014340098A AU 2014340098 A AU2014340098 A AU 2014340098A AU 2014340098 B2 AU2014340098 B2 AU 2014340098B2
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micro
objects
capture
interest
biological
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AU2014340098A1 (en
AU2014340098A8 (en
Inventor
Kevin T. Chapman
M. Jimena LOUREIRO
Daniele Malleo
J. Tanner Nevill
Steven W. Short
Mark P. White
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Bruker Cellular Analysis Inc
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Berkeley Lights Inc
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    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
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    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
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    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

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  • Health & Medical Sciences (AREA)
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  • Food Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
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  • Microelectronics & Electronic Packaging (AREA)
  • Fluid Mechanics (AREA)
  • Computer Hardware Design (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AU2014340098A 2013-10-22 2014-10-22 Micro-fluidic devices for assaying biological activity Active AU2014340098B2 (en)

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AU2020223730A AU2020223730A1 (en) 2013-10-22 2020-08-27 Micro-fluidic devices for assaying biological activity

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US201361996962P 2013-10-22 2013-10-22
US201361996969P 2013-10-22 2013-10-22
US201361996973P 2013-10-22 2013-10-22
US61/996,973 2013-10-22
US61/996,962 2013-10-22
US61/996,969 2013-10-22
US201462058658P 2014-10-01 2014-10-01
US62/058,658 2014-10-01
PCT/US2014/061848 WO2015061506A1 (en) 2013-10-22 2014-10-22 Micro-fluidic devices for assaying biological activity
US14/520,510 2014-10-22
US14/520,510 US9617145B2 (en) 2013-10-22 2014-10-22 Exporting a selected group of micro-objects from a micro-fluidic device

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AU2014340098A1 AU2014340098A1 (en) 2015-04-30
AU2014340098A8 AU2014340098A8 (en) 2019-08-08
AU2014340098B2 true AU2014340098B2 (en) 2020-05-28

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EP (2) EP3783094B1 (https=)
JP (2) JP6465878B2 (https=)
KR (1) KR102113990B1 (https=)
AU (2) AU2014340098B2 (https=)
CA (1) CA2925326C (https=)
IL (2) IL245253B (https=)
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EP3060645B1 (en) 2013-10-22 2019-01-02 Berkeley Lights, Inc. Microfluidic devices having isolation pens and methods of testing biological micro-objects with same
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
US11192107B2 (en) 2014-04-25 2021-12-07 Berkeley Lights, Inc. DEP force control and electrowetting control in different sections of the same microfluidic apparatus
US20150352547A1 (en) 2014-06-06 2015-12-10 Berkeley Lights, Inc. Isolating Microfluidic Structures and Trapping Bubbles
EP3831482B1 (en) 2014-12-08 2024-01-24 Berkeley Lights, Inc. Microfluidic device comprising lateral/vertical transistor structures
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