AU2014332171C1 - Formulations of (S)-3-(4-((4-(morpholinomethyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione - Google Patents

Formulations of (S)-3-(4-((4-(morpholinomethyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione Download PDF

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AU2014332171C1
AU2014332171C1 AU2014332171A AU2014332171A AU2014332171C1 AU 2014332171 C1 AU2014332171 C1 AU 2014332171C1 AU 2014332171 A AU2014332171 A AU 2014332171A AU 2014332171 A AU2014332171 A AU 2014332171A AU 2014332171 C1 AU2014332171 C1 AU 2014332171C1
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dosage form
compound
oral dosage
lactose
amount
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AU2014332171A1 (en
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Anil Menon
Darshan PARIKH
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Celgene Corp
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Celgene Corp
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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AU2014332171A 2013-10-08 2014-10-07 Formulations of (S)-3-(4-((4-(morpholinomethyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione Active AU2014332171C1 (en)

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US201361888419P 2013-10-08 2013-10-08
US61/888,419 2013-10-08
PCT/US2014/059424 WO2015054199A1 (en) 2013-10-08 2014-10-07 Formulations of (s)-3-(4-((4-(morpholinomethyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

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AU2014332171A1 AU2014332171A1 (en) 2016-04-14
AU2014332171B2 AU2014332171B2 (en) 2019-09-12
AU2014332171C1 true AU2014332171C1 (en) 2020-03-26

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TWI745271B (zh) 2014-05-19 2021-11-11 美商西建公司 全身紅斑性狼瘡之治療
ITUB20160650A1 (it) * 2016-02-11 2017-08-11 Dipharma S A Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione
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AU2020206692B2 (en) * 2019-01-09 2025-03-27 Celgene Corporation Pharmaceutical compositions comprising (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and methods of using the same
EP4054623A1 (en) 2019-11-07 2022-09-14 Juno Therapeutics, Inc. Combination of a t cell therapy and (s)-3-[4-(4-morpholin-4 ylmethyl-benzyloxy)-l-oxo-l,3-dihydro-isoindol-2-yl]- piperidine-2,6-dione
KR20220110243A (ko) * 2019-12-02 2022-08-05 셀진 코포레이션 암의 치료를 위한 요법
CN115916191B (zh) * 2020-06-25 2026-06-23 新基公司 用组合疗法治疗癌症的方法
CA3181682A1 (en) * 2020-07-17 2022-01-20 Anil Kapur Subcutaneous telomerase inhibitor compositions and methods for using same
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KR20260088542A (ko) 2023-10-06 2026-06-12 주노 쎄러퓨티크스 인코퍼레이티드 Gprc5d-표적화 car을 발현하는 세포 요법을 사용한 조합 요법 및 관련 방법 및 용도

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