AU2014331954B2 - Methods for treating fibrotic cancers - Google Patents

Methods for treating fibrotic cancers Download PDF

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Publication number
AU2014331954B2
AU2014331954B2 AU2014331954A AU2014331954A AU2014331954B2 AU 2014331954 B2 AU2014331954 B2 AU 2014331954B2 AU 2014331954 A AU2014331954 A AU 2014331954A AU 2014331954 A AU2014331954 A AU 2014331954A AU 2014331954 B2 AU2014331954 B2 AU 2014331954B2
Authority
AU
Australia
Prior art keywords
sap
treatment
cancer
polypeptide
sap polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2014331954A
Other languages
English (en)
Other versions
AU2014331954A1 (en
Inventor
Suzanne Bruhn
Mark LUPHER
Elizabeth TREHU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Promedior Inc
Original Assignee
Promedior Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promedior Inc filed Critical Promedior Inc
Publication of AU2014331954A1 publication Critical patent/AU2014331954A1/en
Application granted granted Critical
Publication of AU2014331954B2 publication Critical patent/AU2014331954B2/en
Priority to AU2020220139A priority Critical patent/AU2020220139A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1716—Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU2014331954A 2013-10-08 2014-10-08 Methods for treating fibrotic cancers Ceased AU2014331954B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020220139A AU2020220139A1 (en) 2013-10-08 2020-08-20 Methods for treating fibrotic cancers

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361888269P 2013-10-08 2013-10-08
US61/888,269 2013-10-08
US201461992807P 2014-05-13 2014-05-13
US61/992,807 2014-05-13
US201462004828P 2014-05-29 2014-05-29
US201462004836P 2014-05-29 2014-05-29
US62/004,828 2014-05-29
US62/004,836 2014-05-29
PCT/US2014/059699 WO2015054390A1 (en) 2013-10-08 2014-10-08 Methods for treating fibrotic cancers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020220139A Division AU2020220139A1 (en) 2013-10-08 2020-08-20 Methods for treating fibrotic cancers

Publications (2)

Publication Number Publication Date
AU2014331954A1 AU2014331954A1 (en) 2016-04-21
AU2014331954B2 true AU2014331954B2 (en) 2020-05-21

Family

ID=52813618

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014331954A Ceased AU2014331954B2 (en) 2013-10-08 2014-10-08 Methods for treating fibrotic cancers
AU2020220139A Abandoned AU2020220139A1 (en) 2013-10-08 2020-08-20 Methods for treating fibrotic cancers

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2020220139A Abandoned AU2020220139A1 (en) 2013-10-08 2020-08-20 Methods for treating fibrotic cancers

Country Status (10)

Country Link
US (2) US11020451B2 (enExample)
EP (2) EP3054959B1 (enExample)
JP (2) JP6636914B2 (enExample)
CN (2) CN114053395A (enExample)
AU (2) AU2014331954B2 (enExample)
CA (1) CA2926418A1 (enExample)
ES (1) ES2784234T3 (enExample)
PL (1) PL3054959T3 (enExample)
RU (2) RU2020111934A (enExample)
WO (1) WO2015054390A1 (enExample)

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RU2020111934A (ru) 2013-10-08 2020-04-29 Промедиор, Инк. Способы лечения фиброзного рака
US20180318303A1 (en) * 2015-04-15 2018-11-08 Promedior, Inc. Methods for treating myeloproliferative disorders
KR102066402B1 (ko) * 2017-12-22 2020-01-15 대화제약 주식회사 이리노테칸 또는 그의 약제학적으로 허용가능한 염을 포함하는 경구투여용 약제학적 조성물
SG11202006782YA (en) * 2018-01-31 2020-08-28 Twi Pharmaceuticals Inc Topical formulations comprising tofacitinib
CA3093749A1 (en) * 2018-03-28 2019-10-03 Blade Therapeutics, Inc. Method of treating fibrotic disease
CN108715865B (zh) * 2018-05-28 2021-09-21 福建师范大学 用于提高细胞转染效率的试剂组合物
CA3128081A1 (en) 2019-02-12 2020-08-20 Ambrx, Inc. Compositions containing, methods and uses of antibody-tlr agonist conjugates
US20220202803A1 (en) * 2019-04-25 2022-06-30 Clear Creek Bio, Inc. Combination therapies including inhibitors of dihydroorotate dehydrogenase
CN112107556A (zh) * 2019-06-03 2020-12-22 北京大学 一种含砷纳米药物及其制备方法
US12441707B2 (en) 2019-12-30 2025-10-14 Tyra Biosciences, Inc. Indazole compounds
US20230089484A1 (en) * 2020-01-28 2023-03-23 Raziel Therapeutics Ltd. Compositions for the treatment of angiolipoma
KR102725907B1 (ko) * 2021-11-25 2024-11-04 성균관대학교산학협력단 파크리티닙을 이용한 항암제 내성 암 치료를 위한 병용 요법
AU2024239074A1 (en) * 2023-03-17 2025-10-02 Mdx Management Llc Compositions and methods for ameliorating adverse effects of therapies

Citations (7)

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Publication number Priority date Publication date Assignee Title
US20070065866A1 (en) * 2002-12-23 2007-03-22 William Marsh Rice University Compositions and Methods for Suppressing Fibrocytes
US20080044429A1 (en) * 2006-06-26 2008-02-21 Macrogenics, Inc. Fc.gamma.RIIB-Specific Antibodies and Methods of Use Thereof
WO2008070117A1 (en) * 2006-12-04 2008-06-12 Promedior, Inc. Conjoint therapy for treating fibrotic diseases
US20090074771A1 (en) * 2002-08-14 2009-03-19 Macrogenics, Inc. FcGammaRIIB Specific Antibodies and Methods of Use Thereof
US20090074754A1 (en) * 2007-07-06 2009-03-19 Promedior, Inc. Methods and compositions useful in the treatment of mucositis
US20090202520A1 (en) * 2007-07-06 2009-08-13 Promedior, Inc. Treatment and diagnostic methods for fibrosis related disorders
WO2010141918A1 (en) * 2009-06-04 2010-12-09 Promedior, Inc. Serum amyloid p derivatives and their preparation and use

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US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
EP0642589A4 (en) 1992-05-11 1997-05-21 Ribozyme Pharm Inc METHOD AND REAGENT TO INHIBIT VIRAL REPLICATION.
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US6395713B1 (en) 1997-07-23 2002-05-28 Ribozyme Pharmaceuticals, Inc. Compositions for the delivery of negatively charged molecules
WO1999004819A1 (en) 1997-07-24 1999-02-04 Inex Pharmaceuticals Corporation Liposomal compositions for the delivery of nucleic acid catalysts
US7115396B2 (en) 1998-12-10 2006-10-03 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
US7763256B2 (en) 2002-12-23 2010-07-27 William Marsh Rice University Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation
EP1711196A4 (en) 2003-12-05 2011-09-14 Bristol Myers Squibb Co INHIBITORS OF TYPE-2 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS
AU2006211960A1 (en) * 2005-02-08 2006-08-17 Board Of Regents, The University Of Texas System Compositions and methods involving MDA-7 for the treatment of cancer
GT200600148A (es) * 2005-04-14 2006-11-22 Metodos para el tratamiento y la prevencion de fibrosis
PL2185581T3 (pl) * 2007-07-06 2016-01-29 Promedior Inc Sposoby i kompozycje użyteczne do leczenia zapalenia błony śluzowej
CA2754961C (en) 2009-03-11 2018-04-10 Promedior, Inc. Treatment and diagnostic methods for hypersensitive disorders
EP2405929B1 (en) * 2009-03-11 2018-06-06 Promedior Inc. A sap polypeptide for use in the treatment of autoimmune disorders and graft vs host disease
JP2012522798A (ja) 2009-04-01 2012-09-27 プロメディオール， インコーポレイテッド 血清アミロイドｐの肺および鼻への送達
EP2987803B1 (en) 2009-06-17 2018-08-29 Promedior Inc. Sap variants and their use
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RU2020111934A (ru) 2013-10-08 2020-04-29 Промедиор, Инк. Способы лечения фиброзного рака
US20180318303A1 (en) 2015-04-15 2018-11-08 Promedior, Inc. Methods for treating myeloproliferative disorders

Patent Citations (7)

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US20090074771A1 (en) * 2002-08-14 2009-03-19 Macrogenics, Inc. FcGammaRIIB Specific Antibodies and Methods of Use Thereof
US20070065866A1 (en) * 2002-12-23 2007-03-22 William Marsh Rice University Compositions and Methods for Suppressing Fibrocytes
US20080044429A1 (en) * 2006-06-26 2008-02-21 Macrogenics, Inc. Fc.gamma.RIIB-Specific Antibodies and Methods of Use Thereof
WO2008070117A1 (en) * 2006-12-04 2008-06-12 Promedior, Inc. Conjoint therapy for treating fibrotic diseases
US20090074754A1 (en) * 2007-07-06 2009-03-19 Promedior, Inc. Methods and compositions useful in the treatment of mucositis
US20090202520A1 (en) * 2007-07-06 2009-08-13 Promedior, Inc. Treatment and diagnostic methods for fibrosis related disorders
WO2010141918A1 (en) * 2009-06-04 2010-12-09 Promedior, Inc. Serum amyloid p derivatives and their preparation and use

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Also Published As

Publication number Publication date
JP2020059752A (ja) 2020-04-16
JP6636914B2 (ja) 2020-01-29
AU2020220139A1 (en) 2020-09-10
CA2926418A1 (en) 2015-04-16
RU2016117775A (ru) 2017-11-15
EP3054959B1 (en) 2020-01-08
US20210322515A1 (en) 2021-10-21
CN114053395A (zh) 2022-02-18
JP2016539087A (ja) 2016-12-15
AU2014331954A1 (en) 2016-04-21
US11020451B2 (en) 2021-06-01
EP3054959A4 (en) 2017-04-26
US20160235812A1 (en) 2016-08-18
PL3054959T3 (pl) 2020-07-13
JP7140739B2 (ja) 2022-09-21
CN105792831A (zh) 2016-07-20
EP3054959A1 (en) 2016-08-17
RU2020111934A (ru) 2020-04-29
EP3718558A1 (en) 2020-10-07
RU2718056C2 (ru) 2020-03-30
WO2015054390A1 (en) 2015-04-16
RU2016117775A3 (enExample) 2018-07-27
ES2784234T3 (es) 2020-09-23

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