AU2014280123B2 - A dosing regime and formulations for type B adenoviruses - Google Patents

A dosing regime and formulations for type B adenoviruses Download PDF

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Publication number
AU2014280123B2
AU2014280123B2 AU2014280123A AU2014280123A AU2014280123B2 AU 2014280123 B2 AU2014280123 B2 AU 2014280123B2 AU 2014280123 A AU2014280123 A AU 2014280123A AU 2014280123 A AU2014280123 A AU 2014280123A AU 2014280123 B2 AU2014280123 B2 AU 2014280123B2
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dose
virus
administered
cancer
coloadl
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AU2014280123A1 (en
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John William Beadle
Kerry Fisher
Christine WILKINSON BLANC
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Akamis Bio Ltd
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Akamis Bio Ltd
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Priority claimed from GB201310698A external-priority patent/GB201310698D0/en
Priority claimed from GB201405140A external-priority patent/GB201405140D0/en
Priority claimed from GB201406509A external-priority patent/GB201406509D0/en
Application filed by Akamis Bio Ltd filed Critical Akamis Bio Ltd
Publication of AU2014280123A1 publication Critical patent/AU2014280123A1/en
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Priority to AU2020201101A priority Critical patent/AU2020201101B2/en
Assigned to Akamis Bio Limited reassignment Akamis Bio Limited Request to Amend Deed and Register Assignors: PSIOXUS THERAUPEUTICS LIMITED
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
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    • A—HUMAN NECESSITIES
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10071—Demonstrated in vivo effect
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2014280123A 2013-06-14 2014-06-12 A dosing regime and formulations for type B adenoviruses Active AU2014280123B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020201101A AU2020201101B2 (en) 2013-06-14 2020-02-14 A dosing regime and formulations for type B adenoviruses

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB201310698A GB201310698D0 (en) 2013-06-14 2013-06-14 Method
GB1310698.4 2013-06-14
GB1405140.3 2014-03-22
GB201405140A GB201405140D0 (en) 2014-03-22 2014-03-22 Method
GB201406509A GB201406509D0 (en) 2014-04-10 2014-04-10 Method
GB1406509.8 2014-04-10
PCT/EP2014/062284 WO2014198852A2 (en) 2013-06-14 2014-06-12 A dosing regime and formulations for type b adenoviruses

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AU2020201101A Division AU2020201101B2 (en) 2013-06-14 2020-02-14 A dosing regime and formulations for type B adenoviruses

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AU2014280123A1 AU2014280123A1 (en) 2016-01-28
AU2014280123B2 true AU2014280123B2 (en) 2019-11-14

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US (2) US11173186B2 (cg-RX-API-DMAC7.html)
EP (2) EP3007711B1 (cg-RX-API-DMAC7.html)
JP (2) JP6797680B2 (cg-RX-API-DMAC7.html)
KR (3) KR20210054067A (cg-RX-API-DMAC7.html)
CN (2) CN112516179A (cg-RX-API-DMAC7.html)
AU (2) AU2014280123B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015030881A2 (cg-RX-API-DMAC7.html)
CA (2) CA3176971A1 (cg-RX-API-DMAC7.html)
IL (1) IL243071B (cg-RX-API-DMAC7.html)
RU (1) RU2671558C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201510064WA (cg-RX-API-DMAC7.html)
WO (1) WO2014198852A2 (cg-RX-API-DMAC7.html)

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