AU2014248605B2 - Methods and compositions for modification of HLA - Google Patents

Methods and compositions for modification of HLA Download PDF

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Publication number
AU2014248605B2
AU2014248605B2 AU2014248605A AU2014248605A AU2014248605B2 AU 2014248605 B2 AU2014248605 B2 AU 2014248605B2 AU 2014248605 A AU2014248605 A AU 2014248605A AU 2014248605 A AU2014248605 A AU 2014248605A AU 2014248605 B2 AU2014248605 B2 AU 2014248605B2
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AU
Australia
Prior art keywords
hla
seq
cells
cell
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2014248605A
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English (en)
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AU2014248605A1 (en
Inventor
Laurence J.N. Cooper
Philip D. Gregory
Hiroki TORIKAI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sangamo Therapeutics Inc
University of Texas System
Original Assignee
Sangamo Therapeutics Inc
University of Texas System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sangamo Therapeutics Inc, University of Texas System, University of Texas at Austin filed Critical Sangamo Therapeutics Inc
Publication of AU2014248605A1 publication Critical patent/AU2014248605A1/en
Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, SANGAMO THERAPEUTICS, INC. reassignment BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM Alteration of Name(s) of Applicant(s) under S113 Assignors: SANGAMO BIOSCIENCES, INC.
Application granted granted Critical
Publication of AU2014248605B2 publication Critical patent/AU2014248605B2/en
Priority to AU2020203765A priority Critical patent/AU2020203765A1/en
Priority to AU2022211891A priority patent/AU2022211891A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
    • A61K40/4211—CD19 or B4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
AU2014248605A 2013-03-12 2014-03-12 Methods and compositions for modification of HLA Ceased AU2014248605B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020203765A AU2020203765A1 (en) 2013-03-12 2020-06-08 Methods And Compositions For Modification of HLA
AU2022211891A AU2022211891A1 (en) 2013-03-12 2022-08-04 Methods And Compositions For Modification of HLA

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361777627P 2013-03-12 2013-03-12
US61/777,627 2013-03-12
PCT/US2014/024660 WO2014165177A1 (en) 2013-03-12 2014-03-12 Methods and compositions for modification of hla

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020203765A Division AU2020203765A1 (en) 2013-03-12 2020-06-08 Methods And Compositions For Modification of HLA

Publications (2)

Publication Number Publication Date
AU2014248605A1 AU2014248605A1 (en) 2015-09-24
AU2014248605B2 true AU2014248605B2 (en) 2020-05-28

Family

ID=51659088

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2014248605A Ceased AU2014248605B2 (en) 2013-03-12 2014-03-12 Methods and compositions for modification of HLA
AU2020203765A Abandoned AU2020203765A1 (en) 2013-03-12 2020-06-08 Methods And Compositions For Modification of HLA
AU2022211891A Abandoned AU2022211891A1 (en) 2013-03-12 2022-08-04 Methods And Compositions For Modification of HLA

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2020203765A Abandoned AU2020203765A1 (en) 2013-03-12 2020-06-08 Methods And Compositions For Modification of HLA
AU2022211891A Abandoned AU2022211891A1 (en) 2013-03-12 2022-08-04 Methods And Compositions For Modification of HLA

Country Status (9)

Country Link
US (3) US20150037304A1 (enExample)
EP (1) EP2970886B1 (enExample)
JP (1) JP6433480B2 (enExample)
CN (1) CN105283539A (enExample)
AU (3) AU2014248605B2 (enExample)
CA (1) CA2904210C (enExample)
HK (1) HK1217968A1 (enExample)
IL (1) IL241112B (enExample)
WO (1) WO2014165177A1 (enExample)

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US11661590B2 (en) 2016-08-09 2023-05-30 President And Fellows Of Harvard College Programmable CAS9-recombinase fusion proteins and uses thereof
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Also Published As

Publication number Publication date
IL241112B (en) 2021-02-28
JP2016513460A (ja) 2016-05-16
IL241112A0 (en) 2015-11-30
EP2970886A1 (en) 2016-01-20
CA2904210C (en) 2022-07-19
JP6433480B2 (ja) 2018-12-05
EP2970886B1 (en) 2018-05-23
CN105283539A (zh) 2016-01-27
AU2020203765A1 (en) 2020-06-25
US20150037304A1 (en) 2015-02-05
AU2014248605A1 (en) 2015-09-24
CA2904210A1 (en) 2014-10-09
WO2014165177A1 (en) 2014-10-09
US20220202858A1 (en) 2022-06-30
US20170216358A1 (en) 2017-08-03
HK1217968A1 (zh) 2017-01-27
AU2022211891A1 (en) 2022-09-01
EP2970886A4 (en) 2016-08-17

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

Free format text: FORMER NAME(S): SANGAMO BIOSCIENCES, INC.

Owner name: SANGAMO THERAPEUTICS, INC.

Free format text: FORMER NAME(S): SANGAMO BIOSCIENCES, INC.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired