AU2014245806B2 - Microfluidic devices and methods for use thereof in multicellular assays of secretion - Google Patents

Microfluidic devices and methods for use thereof in multicellular assays of secretion Download PDF

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AU2014245806B2
AU2014245806B2 AU2014245806A AU2014245806A AU2014245806B2 AU 2014245806 B2 AU2014245806 B2 AU 2014245806B2 AU 2014245806 A AU2014245806 A AU 2014245806A AU 2014245806 A AU2014245806 A AU 2014245806A AU 2014245806 B2 AU2014245806 B2 AU 2014245806B2
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cell
readout
cells
population
antibody
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AU2014245806A9 (en
AU2014245806A1 (en
Inventor
J. Daniel Da Costa
Carl L. G. Hansen
Kevin Albert HEYRIES
Veronique Lecault
Kathleen LISAINGO
Brad Nelson
Julie NIELSEN
Oleh Petriv
Marketa RICICOVA
Anupam Singhal
Hans Zahn
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University of British Columbia
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    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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AU2014245806A 2013-03-28 2014-03-28 Microfluidic devices and methods for use thereof in multicellular assays of secretion Active AU2014245806B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020200414A AU2020200414B2 (en) 2013-03-28 2020-01-21 Microfluidic devices and methods for use thereof in multicellular assays of secretion
AU2022202333A AU2022202333B2 (en) 2013-03-28 2022-04-07 Microfluidic devices and methods for use thereof in multicellular assays of secretion

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361806329P 2013-03-28 2013-03-28
US61/806,329 2013-03-28
PCT/CA2014/000304 WO2014153651A1 (en) 2013-03-28 2014-03-28 Microfluidic devices and methods for use thereof in multicellular assays of secretion

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AU2020200414A Division AU2020200414B2 (en) 2013-03-28 2020-01-21 Microfluidic devices and methods for use thereof in multicellular assays of secretion

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AU2014245806A1 AU2014245806A1 (en) 2015-09-24
AU2014245806A9 AU2014245806A9 (en) 2016-06-16
AU2014245806B2 true AU2014245806B2 (en) 2019-10-31

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AU2014245806A Active AU2014245806B2 (en) 2013-03-28 2014-03-28 Microfluidic devices and methods for use thereof in multicellular assays of secretion
AU2020200414A Active AU2020200414B2 (en) 2013-03-28 2020-01-21 Microfluidic devices and methods for use thereof in multicellular assays of secretion
AU2022202333A Active AU2022202333B2 (en) 2013-03-28 2022-04-07 Microfluidic devices and methods for use thereof in multicellular assays of secretion

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AU2022202333A Active AU2022202333B2 (en) 2013-03-28 2022-04-07 Microfluidic devices and methods for use thereof in multicellular assays of secretion

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US (3) US10725024B2 (https=)
EP (2) EP2978855B1 (https=)
JP (4) JP6608803B2 (https=)
KR (3) KR102668221B1 (https=)
CN (3) CN115074413A (https=)
AU (3) AU2014245806B2 (https=)
CA (2) CA3234004A1 (https=)
NZ (1) NZ711723A (https=)
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US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9752113B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc. Acoustic perfusion devices
US10689609B2 (en) 2012-03-15 2020-06-23 Flodesign Sonics, Inc. Acoustic bioreactor processes
US9752114B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc Bioreactor using acoustic standing waves
US9796956B2 (en) 2013-11-06 2017-10-24 Flodesign Sonics, Inc. Multi-stage acoustophoresis device
US10370635B2 (en) 2012-03-15 2019-08-06 Flodesign Sonics, Inc. Acoustic separation of T cells
US9745548B2 (en) 2012-03-15 2017-08-29 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
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