AU2013275761B2 - Biomarkers for prostate cancer - Google Patents

Biomarkers for prostate cancer Download PDF

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Publication number
AU2013275761B2
AU2013275761B2 AU2013275761A AU2013275761A AU2013275761B2 AU 2013275761 B2 AU2013275761 B2 AU 2013275761B2 AU 2013275761 A AU2013275761 A AU 2013275761A AU 2013275761 A AU2013275761 A AU 2013275761A AU 2013275761 B2 AU2013275761 B2 AU 2013275761B2
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seq
c1orf114
methylation
nucleotide sequence
basepair
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AU2013275761A1 (en
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Karina Dalsgaard Sorensen
Torben Falck Orntoft
Christa HALDRUP
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Aarhus Universitet
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Aarhus Universitet
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Primary Health Care (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2013275761A 2012-06-14 2013-06-14 Biomarkers for prostate cancer Active AU2013275761B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201270326 2012-06-14
DKPA201270326 2012-06-14
PCT/DK2013/050196 WO2013185779A2 (en) 2012-06-14 2013-06-14 Biomarkers for prostate cancer

Publications (2)

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AU2013275761A1 AU2013275761A1 (en) 2015-01-22
AU2013275761B2 true AU2013275761B2 (en) 2017-09-28

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AU2013275761A Active AU2013275761B2 (en) 2012-06-14 2013-06-14 Biomarkers for prostate cancer

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US (1) US10106854B2 (enExample)
EP (1) EP2861759B1 (enExample)
JP (1) JP6242388B2 (enExample)
AU (1) AU2013275761B2 (enExample)
CA (1) CA2876252A1 (enExample)
WO (1) WO2013185779A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3037545A1 (en) * 2014-12-23 2016-06-29 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin A DNA-methylation test for prostate cancer
CN107532124B (zh) 2015-03-27 2022-08-09 精密科学公司 检测食管疾病
CN106480169B (zh) * 2015-09-01 2019-10-08 杨小丽 人aqp10和sox17基因甲基化位点的检测和应用
CA3054836A1 (en) * 2017-02-28 2018-09-07 Mayo Foundation For Medical Education And Research Detecting prostate cancer
GB201816820D0 (en) 2018-10-16 2018-11-28 Univ York Diagnostic method
WO2020099277A1 (en) 2018-11-13 2020-05-22 Bracco Imaging Spa Gene signatures for the prediction of prostate cancer recurrence
CN109468381B (zh) * 2018-11-19 2022-11-25 兰州市第一人民医院 用于宫颈癌筛查的甲基化位点及其检测引物
EP3999662A1 (en) * 2019-07-19 2022-05-25 Vilnius University Characterization of prostate cancer using dna methylation assay system
CN113122636A (zh) * 2020-01-14 2021-07-16 上海鹍远生物技术有限公司 检测dna甲基化的试剂及用途
US20230167506A1 (en) * 2020-05-04 2023-06-01 Mayo Foundation For Medical Education And Research Detecting pancreatic neuroendocrine tumors
WO2021226110A1 (en) * 2020-05-05 2021-11-11 The Board Of Trustees Of The Leland Stanford Junior University Cell-free dna biomarkers and their use in diagnosis, monitoring response to therapy, and selection of therapy for prostate cancer
CN118685523B (zh) * 2024-08-26 2024-11-15 湖南宏雅基因技术有限公司 一种用于前列腺癌检测的生物标志物组合、引物探针组合物及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010080933A1 (en) * 2009-01-07 2010-07-15 Myriad Genetics, Inc Cancer biomarkers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6605432B1 (en) 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
DE60232059D1 (de) * 2001-03-01 2009-06-04 Epigenomics Ag Verfahren zur entwicklung von gensätzen zu diagnostischen und therapeutischen zwecken auf grundlage des expressions- und methylierungsstatus der gene
WO2008143896A1 (en) * 2007-05-14 2008-11-27 The Johns Hopkins University Methylation markers for prostate cancer and methods of use
CN102308003A (zh) * 2008-08-05 2012-01-04 维里德克斯有限责任公司 前列腺癌甲基化分析法
US20100303795A1 (en) 2009-05-27 2010-12-02 Soerensen Karina Dalsgaard Marker of prostate cancer
WO2011027310A1 (en) * 2009-09-03 2011-03-10 Koninklijke Philips Electronics N.V. Novel tumor markers
WO2011037936A2 (en) * 2009-09-24 2011-03-31 Oregon Health & Science University Detection of dna methylation of tal1, erg and/or cd40 to diagnose prostate cancer
WO2011044902A1 (en) 2009-10-13 2011-04-21 Aarhus Universitet Tff3 hypomethylation as a novel biomarker for prostate cancer
WO2011112845A2 (en) * 2010-03-11 2011-09-15 Board Of Regents, The University Of Texas System Methods and compositions related to a multi-methylation assay to predict patient outcome
US20140094380A1 (en) * 2011-04-04 2014-04-03 The Board Of Trustees Of The Leland Stanford Junior University Methylation Biomarkers for Diagnosis of Prostate Cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010080933A1 (en) * 2009-01-07 2010-07-15 Myriad Genetics, Inc Cancer biomarkers

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIBIKOVA, M. et al., "High density DNA methylation array with single CpG site resolution", Genomics, 2011, Vol. 98, pages 288-295 *
GEO Accession No. GPL8490, Illumina HumanMethylation27 Beadchip, 27 April 2009 *

Also Published As

Publication number Publication date
US10106854B2 (en) 2018-10-23
JP2015527875A (ja) 2015-09-24
JP6242388B2 (ja) 2017-12-06
US20150152507A1 (en) 2015-06-04
EP2861759A2 (en) 2015-04-22
WO2013185779A3 (en) 2014-02-06
CA2876252A1 (en) 2013-12-19
WO2013185779A2 (en) 2013-12-19
AU2013275761A1 (en) 2015-01-22
EP2861759B1 (en) 2025-06-04

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