AU2013262991A1 - Methods of using (4S,4aS,5aR,12aS)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide - Google Patents

Methods of using (4S,4aS,5aR,12aS)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide Download PDF

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Publication number
AU2013262991A1
AU2013262991A1 AU2013262991A AU2013262991A AU2013262991A1 AU 2013262991 A1 AU2013262991 A1 AU 2013262991A1 AU 2013262991 A AU2013262991 A AU 2013262991A AU 2013262991 A AU2013262991 A AU 2013262991A AU 2013262991 A1 AU2013262991 A1 AU 2013262991A1
Authority
AU
Australia
Prior art keywords
methyl
salt
mono
crystalline
naphthacene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2013262991A
Other languages
English (en)
Inventor
Catherine COULTER
Sean M. Johnston
Farzaneh Seyedi
Tina M. Devries
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Paratek Pharmaceuticals Inc
Warner Chilcott Co LLC
Original Assignee
Paratek Pharmaceuticals Inc
Warner Chilcott Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharmaceuticals Inc, Warner Chilcott Co LLC filed Critical Paratek Pharmaceuticals Inc
Publication of AU2013262991A1 publication Critical patent/AU2013262991A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2013262991A 2012-05-14 2013-05-14 Methods of using (4S,4aS,5aR,12aS)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide Abandoned AU2013262991A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261646754P 2012-05-14 2012-05-14
US61/646,754 2012-05-14
PCT/US2013/040933 WO2013173326A1 (en) 2012-05-14 2013-05-14 Methods of using (4s,4as,5ar,12as)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide

Publications (1)

Publication Number Publication Date
AU2013262991A1 true AU2013262991A1 (en) 2014-12-04

Family

ID=49548796

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013262991A Abandoned AU2013262991A1 (en) 2012-05-14 2013-05-14 Methods of using (4S,4aS,5aR,12aS)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide

Country Status (6)

Country Link
US (1) US20130302442A1 (https=)
EP (1) EP2849757A4 (https=)
JP (1) JP2015517524A (https=)
AU (1) AU2013262991A1 (https=)
CA (1) CA2873412A1 (https=)
WO (1) WO2013173326A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9255068B2 (en) * 2011-05-12 2016-02-09 Warner Chilcott Company, Llc Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same
AU2016235151A1 (en) * 2015-03-24 2017-10-12 Paratek Pharmaceuticals, Inc. Minocycline compounds for biodefense
AU2019248350B2 (en) * 2018-04-06 2023-07-27 Almirall, Llc Process for making sarecycline hydrochloride

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0375068A1 (en) * 1988-12-23 1990-06-27 Gist-Brocades N.V. Combining bismuth compounds and tetracyclines
JP2007524693A (ja) * 2004-02-20 2007-08-30 ザ バーナム インスティチュート 抗菌性の糖質及びそれを用いた方法
WO2008079339A2 (en) * 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
CA2892739A1 (en) * 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
NO2470500T3 (https=) * 2009-08-28 2018-03-03
WO2012021829A1 (en) * 2010-08-12 2012-02-16 Tetraphase Pharmaceuticals, Inc. Methods of treating bacterial infections
US9255068B2 (en) * 2011-05-12 2016-02-09 Warner Chilcott Company, Llc Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same

Also Published As

Publication number Publication date
WO2013173326A1 (en) 2013-11-21
US20130302442A1 (en) 2013-11-14
JP2015517524A (ja) 2015-06-22
CA2873412A1 (en) 2013-11-21
EP2849757A4 (en) 2015-11-18
EP2849757A1 (en) 2015-03-25

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period