AU2013226402B2 - Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features - Google Patents
Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features Download PDFInfo
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- AU2013226402B2 AU2013226402B2 AU2013226402A AU2013226402A AU2013226402B2 AU 2013226402 B2 AU2013226402 B2 AU 2013226402B2 AU 2013226402 A AU2013226402 A AU 2013226402A AU 2013226402 A AU2013226402 A AU 2013226402A AU 2013226402 B2 AU2013226402 B2 AU 2013226402B2
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pest Control & Pesticides (AREA)
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- Dentistry (AREA)
- Biomedical Technology (AREA)
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- Agronomy & Crop Science (AREA)
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- Nutrition Science (AREA)
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- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
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| US201261603661P | 2012-02-27 | 2012-02-27 | |
| US61/603,661 | 2012-02-27 | ||
| US61/603,693 | 2012-02-27 | ||
| PCT/US2013/027336 WO2013130349A1 (en) | 2012-02-27 | 2013-02-22 | Variants of the lantibiotic mu1140 and other lantibiotics with improved pharmacological properties and structural features |
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| AU2013226402A1 AU2013226402A1 (en) | 2014-08-21 |
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| AU2013226404A Ceased AU2013226404B2 (en) | 2012-02-27 | 2013-02-22 | Replacement therapy for dental caries |
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| AU2013226404A Ceased AU2013226404B2 (en) | 2012-02-27 | 2013-02-22 | Replacement therapy for dental caries |
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| EP (3) | EP2833902A4 (enExample) |
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| MX (2) | MX369443B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201810952PA (en) * | 2016-07-15 | 2019-01-30 | Intrexon Corp | Lantibiotic variants and uses thereof |
| US10577399B2 (en) | 2016-10-28 | 2020-03-03 | The Texas A&M University System | Modified lantibiotics and methods of making and using the modified lantibiotics |
| WO2020090045A1 (ja) * | 2018-10-31 | 2020-05-07 | 株式会社村田製作所 | 抗グラム陰性菌化合物 |
| EP3935067A4 (en) * | 2019-03-08 | 2022-12-07 | Fraunhofer USA, Inc. | NEW ANTIMICROBIAL LANTIBIOTIC PEPTIDE AND ASSOCIATED USES |
| CN118490568B (zh) * | 2024-07-16 | 2024-10-18 | 南昌怀特科技有限公司 | 一种用于牙齿美白的抑菌凝胶及其制备方法与应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1996016180A1 (en) * | 1994-11-19 | 1996-05-30 | Institute Of Food Research | Production of variant nisin |
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| US4366246A (en) | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
| US5516682A (en) | 1988-07-05 | 1996-05-14 | University Of Maryland | Subtilin variant of enhanced stability and activity |
| US20060198793A1 (en) * | 1997-06-10 | 2006-09-07 | University Of Florida Research Foundation | Antimicrobial polypeptide, nucleic acid, and methods of use |
| US5932469A (en) * | 1997-06-10 | 1999-08-03 | University Of Florida | Antimicrobial polypeptide, nucleic acid, and methods of use |
| US6964760B2 (en) | 1997-06-10 | 2005-11-15 | University Of Florida Research Foundation | Antimicrobial polypeptide, nucleic acid, and methods of use |
| US6251478B1 (en) | 1999-12-22 | 2001-06-26 | Balchem Corporation | Sensitive substance encapsulation |
| EP1483366B1 (en) * | 2002-02-22 | 2010-04-14 | Blis Technologies Limited | Antimicrobial composition |
| ATE512158T1 (de) | 2005-08-12 | 2011-06-15 | Oragenics Inc | Differenziell geschützte, orthogonale lanthionintechnologie |
| US20090215985A1 (en) * | 2005-08-12 | 2009-08-27 | Oragenics, Inc. | Differentially protected orthogonal lanthionine technology |
| US7576054B2 (en) * | 2005-10-11 | 2009-08-18 | Biosynexus Incorporated | Compositions and methods for treating bacteria |
| US20110150917A1 (en) * | 2007-06-12 | 2011-06-23 | The University Of British Columbia | Small Cationic Antimicrobial Peptides |
| DK2176284T3 (da) * | 2007-07-20 | 2013-10-14 | Univ Minnesota | Lantibiotika og anvendelser deraf |
| IE20080365A1 (en) * | 2008-05-09 | 2010-03-16 | Univ College Cork Nat Univ Ie | Nisin derivatives and the use thereof |
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2013
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- 2013-02-22 CN CN201380011187.9A patent/CN104302307B/zh not_active Expired - Fee Related
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- 2013-02-22 BR BR112014020656A patent/BR112014020656A2/pt not_active Application Discontinuation
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1996016180A1 (en) * | 1994-11-19 | 1996-05-30 | Institute Of Food Research | Production of variant nisin |
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