ATE512158T1 - Differenziell geschützte, orthogonale lanthionintechnologie - Google Patents
Differenziell geschützte, orthogonale lanthionintechnologieInfo
- Publication number
- ATE512158T1 ATE512158T1 AT06789722T AT06789722T ATE512158T1 AT E512158 T1 ATE512158 T1 AT E512158T1 AT 06789722 T AT06789722 T AT 06789722T AT 06789722 T AT06789722 T AT 06789722T AT E512158 T1 ATE512158 T1 AT E512158T1
- Authority
- AT
- Austria
- Prior art keywords
- provides
- synthesizing
- present
- differentially protected
- intramolecularly bridged
- Prior art date
Links
- DWPCPZJAHOETAG-IMJSIDKUSA-N L-lanthionine Chemical compound OC(=O)[C@@H](N)CSC[C@H](N)C(O)=O DWPCPZJAHOETAG-IMJSIDKUSA-N 0.000 title 1
- DWPCPZJAHOETAG-UHFFFAOYSA-N meso-lanthionine Natural products OC(=O)C(N)CSCC(N)C(O)=O DWPCPZJAHOETAG-UHFFFAOYSA-N 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 230000002194 synthesizing effect Effects 0.000 abstract 3
- 108010062877 Bacteriocins Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/062—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha- or omega-carboxy functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Materials For Medical Uses (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70808605P | 2005-08-12 | 2005-08-12 | |
| US80890706P | 2006-05-26 | 2006-05-26 | |
| PCT/US2006/031510 WO2007022012A2 (en) | 2005-08-12 | 2006-08-11 | Differentially protected orthogonal lanthionine technology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE512158T1 true ATE512158T1 (de) | 2011-06-15 |
Family
ID=37460062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06789722T ATE512158T1 (de) | 2005-08-12 | 2006-08-11 | Differenziell geschützte, orthogonale lanthionintechnologie |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7521529B2 (de) |
| EP (1) | EP1915389B1 (de) |
| JP (1) | JP4955001B2 (de) |
| AT (1) | ATE512158T1 (de) |
| AU (1) | AU2006279749B2 (de) |
| CA (1) | CA2618066A1 (de) |
| DK (1) | DK1915389T3 (de) |
| NZ (1) | NZ566546A (de) |
| WO (1) | WO2007022012A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090215985A1 (en) * | 2005-08-12 | 2009-08-27 | Oragenics, Inc. | Differentially protected orthogonal lanthionine technology |
| JP2010170886A (ja) * | 2009-01-23 | 2010-08-05 | Sony Corp | 電解質および二次電池 |
| WO2010091142A1 (en) * | 2009-02-04 | 2010-08-12 | President And Fellows Of Harvard College | Compositions and methods for labeling and imaging phospholipids |
| EP2267003A1 (de) * | 2009-06-24 | 2010-12-29 | Applied NanoSystems B.V. | Biologisch hergestellte cyclische Affinitätsmarker |
| HK1205458A1 (en) | 2012-02-27 | 2015-12-18 | Oragenics, Inc. | Variants of the lantibiotic mu1140 and other lantibiotics with improved pharmacological properties and structural features |
| WO2014093196A1 (en) * | 2012-12-10 | 2014-06-19 | North Carolina State University | Solid phase scaffold based libraries |
| CN103601640B (zh) * | 2013-11-13 | 2015-07-29 | 迈克斯(如东)化工有限公司 | 一种环己烷三酮类化合物的制备方法 |
| EP3122764B1 (de) * | 2014-03-25 | 2019-01-16 | LanthioPep B.V. | Cyclische apelinanaloga |
| CN104478689A (zh) * | 2015-01-09 | 2015-04-01 | 泰州施美康多肽药物技术有限公司 | 一种ivDde-OH的纯化方法 |
| JP2019529344A (ja) | 2016-07-15 | 2019-10-17 | イントレキソン コーポレーション | ランチビオティックバリアントおよびその使用 |
| EP3612549A4 (de) * | 2017-04-21 | 2021-05-26 | Memorial Sloan-Kettering Cancer Center | Lantibiotika, lantibiotikaproduzierende bakterien, zusammensetzungen und verfahren zur herstellung und verwendung davon |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256549A (en) * | 1986-03-28 | 1993-10-26 | Chiron Corporation | Purification of synthetic oligomers |
| US5049656A (en) | 1988-12-21 | 1991-09-17 | Board Of Regents Of The University Of Nebraska | Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques |
| US6028168A (en) * | 1991-08-09 | 2000-02-22 | Winfried Kolbeck | Lanthionine bridged peptides |
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US6794181B2 (en) * | 2002-10-09 | 2004-09-21 | Immucell Corporation | Method of purifying lantibiotics |
| US7785825B2 (en) * | 2004-01-12 | 2010-08-31 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics |
-
2006
- 2006-08-11 AT AT06789722T patent/ATE512158T1/de not_active IP Right Cessation
- 2006-08-11 DK DK06789722.3T patent/DK1915389T3/da active
- 2006-08-11 JP JP2008526260A patent/JP4955001B2/ja not_active Expired - Fee Related
- 2006-08-11 WO PCT/US2006/031510 patent/WO2007022012A2/en not_active Ceased
- 2006-08-11 US US11/502,805 patent/US7521529B2/en not_active Expired - Fee Related
- 2006-08-11 AU AU2006279749A patent/AU2006279749B2/en not_active Ceased
- 2006-08-11 CA CA002618066A patent/CA2618066A1/en not_active Abandoned
- 2006-08-11 EP EP06789722A patent/EP1915389B1/de not_active Not-in-force
- 2006-08-11 NZ NZ566546A patent/NZ566546A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1915389B1 (de) | 2011-06-08 |
| EP1915389A2 (de) | 2008-04-30 |
| JP4955001B2 (ja) | 2012-06-20 |
| NZ566546A (en) | 2011-01-28 |
| AU2006279749A1 (en) | 2007-02-22 |
| AU2006279749B2 (en) | 2012-12-20 |
| US7521529B2 (en) | 2009-04-21 |
| US20070037963A1 (en) | 2007-02-15 |
| HK1112925A1 (en) | 2008-09-19 |
| JP2009505981A (ja) | 2009-02-12 |
| CA2618066A1 (en) | 2007-02-22 |
| WO2007022012A3 (en) | 2007-08-30 |
| DK1915389T3 (da) | 2011-09-19 |
| WO2007022012A2 (en) | 2007-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |