AU2013216993C1 - Timothy Grass allergens and methods and uses for immune response modulation - Google Patents

Timothy Grass allergens and methods and uses for immune response modulation Download PDF

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Publication number
AU2013216993C1
AU2013216993C1 AU2013216993A AU2013216993A AU2013216993C1 AU 2013216993 C1 AU2013216993 C1 AU 2013216993C1 AU 2013216993 A AU2013216993 A AU 2013216993A AU 2013216993 A AU2013216993 A AU 2013216993A AU 2013216993 C1 AU2013216993 C1 AU 2013216993C1
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AU
Australia
Prior art keywords
seq
nos
amino acid
protein
peptide
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AU2013216993A
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English (en)
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AU2013216993B2 (en
AU2013216993A1 (en
Inventor
Jason GREENBAUM
Howard Grey
Bjoern Peters
Veronique SCHULTEN
Alessandro Sette
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La Jolla Institute for Allergy and Immunology
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La Jolla Institute for Allergy and Immunology
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Publication of AU2013216993A1 publication Critical patent/AU2013216993A1/en
Assigned to LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY reassignment LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY Amend patent request/document other than specification (104) Assignors: ALESSANDRO SETTE, BJOERN PETERS, HOWARD GREY, JASON GREENBAUM, LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, VERONIQUE SCHULTEN
Publication of AU2013216993B2 publication Critical patent/AU2013216993B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AU2013216993A 2012-02-07 2013-02-07 Timothy Grass allergens and methods and uses for immune response modulation Ceased AU2013216993C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261596156P 2012-02-07 2012-02-07
US61/596,156 2012-02-07
US201261734886P 2012-12-07 2012-12-07
US61/734,886 2012-12-07
PCT/US2013/025213 WO2013119863A1 (en) 2012-02-07 2013-02-07 Timothy grass allergens and methods and uses for immune response modulation

Publications (3)

Publication Number Publication Date
AU2013216993A1 AU2013216993A1 (en) 2014-08-21
AU2013216993B2 AU2013216993B2 (en) 2016-09-15
AU2013216993C1 true AU2013216993C1 (en) 2017-01-19

Family

ID=48948025

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013216993A Ceased AU2013216993C1 (en) 2012-02-07 2013-02-07 Timothy Grass allergens and methods and uses for immune response modulation

Country Status (13)

Country Link
US (1) US10428124B2 (https=)
EP (1) EP2812026A4 (https=)
JP (1) JP2015513527A (https=)
KR (1) KR20140129124A (https=)
CN (1) CN104203277A (https=)
AU (1) AU2013216993C1 (https=)
BR (1) BR112014019504A2 (https=)
CA (1) CA2864084A1 (https=)
EA (1) EA201491481A1 (https=)
HK (1) HK1204929A1 (https=)
IN (1) IN2014MN01513A (https=)
MX (1) MX2014009285A (https=)
WO (1) WO2013119863A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015054217A2 (en) 2013-10-07 2015-04-16 La Jolla Institute For Allergy And Immunology Methods and uses for reducing an allergic response in a subject
WO2015054231A1 (en) 2013-10-07 2015-04-16 La Jolla Institute For Allergy And Immunology Methods and uses for identifying responders to allergy therapy
WO2015077442A2 (en) 2013-11-20 2015-05-28 La Jolla Institute For Allergy And Immunology Grass pollen immunogens and methods and uses for immune response modulation
AU2014352986A1 (en) 2013-11-20 2016-06-16 Alk-Abello A/S Pan pollen immunogens and methods and uses thereof for immune response modulation
BR112016011930A2 (pt) 2013-12-23 2017-09-26 Alk Abello As combinações de peptídeos e seus usos em tratamento de alergia de ácaro de poeira
WO2015131053A1 (en) 2014-02-28 2015-09-03 Alk-Abelló A/S Polypeptides derived from phl p and methods and uses thereof for immune response modulation
EP3925968A3 (en) 2014-10-07 2022-03-02 Cytlimic Inc. Hsp70-derived peptide, pharmaceutical composition for treating or preventing cancer using same, immunity inducer, and method for producing antigen-presenting cell
CN113388021A (zh) 2015-03-09 2021-09-14 Cytlimic公司 源于gpc3的肽、使用其的医药组合物、免疫诱导剂、及抗原呈递细胞的制造方法
RU2709015C2 (ru) 2015-04-07 2019-12-13 Ситлимик Инк. Лекарственное средство
CA3023092A1 (en) * 2016-05-03 2017-11-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to induce tolerance
US11291718B2 (en) 2016-10-11 2022-04-05 Cytlimic Inc. Method for treating cancer by administering a toll-like receptor agonist and LAG-3 IgG fusion protein
CN119086940A (zh) * 2017-04-28 2024-12-06 朋友股份有限公司 变态反应的抗原及其表位
JP7770314B2 (ja) * 2019-11-25 2025-11-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 診断及び処置のための抗原ニューロン特異的エノラーゼペプチド
CN120349374B (zh) * 2025-03-25 2025-10-10 长沙理工大学 一种米渣短肽及其在降尿酸中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090070897A1 (en) * 2006-01-12 2009-03-12 Goldman Barry S Genes and uses for plant improvement

Family Cites Families (12)

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US7214786B2 (en) * 2000-12-14 2007-05-08 Kovalic David K Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
AUPR775401A0 (en) * 2001-09-18 2001-10-11 Monash University Novel Epitopes and Uses Thereof
EP2392591B1 (de) * 2002-06-25 2018-02-21 Merck Patent GmbH DNA-Sequenz und rekombinante Herstellung des Graspollen-Allergens Phl p 4
RU2323942C2 (ru) 2002-08-19 2008-05-10 Мерк Патент Гмбх ВАРИАНТЫ ОСНОВНОГО АЛЛЕРГЕНА Phl p 1 ИЗ ТИМОФЕЕВКИ ЛУГОВОЙ
WO2004047793A1 (en) * 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
AU2006204997B2 (en) 2005-01-12 2011-09-01 Monsanto Technology, Llc Genes and uses for plant improvement
PL2244734T3 (pl) * 2008-02-01 2017-01-31 Murdoch Childrens Research Institute Sposób indukcji tolerancji na alergen
EP2388268A1 (en) * 2010-05-18 2011-11-23 Stallergenes S.A. Recombinant Der p 2 expressed in Pichia pastoris as a "natural-like" allergen for immunotherapy and diagnostic purposes
US20120100163A1 (en) 2010-10-15 2012-04-26 Alk-Abello A/S Suppression of a type 1 hypersensitivity immune response with an unrelated antigen
US20120100164A1 (en) 2010-10-15 2012-04-26 Alk-Abello A/S Suppression of a hypersensitivity immune response with unrelated antigen derived from allergen source material
US9700071B2 (en) * 2012-03-26 2017-07-11 Axcella Health Inc. Nutritive fragments, proteins and methods
JP2015514126A (ja) 2012-04-16 2015-05-18 アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ 非特異的アレルギー免疫療法において使用するための植物プロフィリンポリペプチド

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090070897A1 (en) * 2006-01-12 2009-03-12 Goldman Barry S Genes and uses for plant improvement

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CORTI, V. et al. :"Identification of grass pollen allergens by two-dimensional gel electrophoresis and serological screening",Proteomics, 2005, Vol.5, pages 729-736 *
PERSSON, H. et al.: "A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2", Molecular Immunology, 2008, Vol.45, pages 2715-2720 *
VRTALA, S. et al., "cDNA Cloning of a Major Allergen from Timothy Grass (Phleum pratense) Pollen; Characterization of the Recombinant Phl p V Allergen", The Journal of Immunology, (1993), Vol. 151, No.9 pages 4773-4781 *

Also Published As

Publication number Publication date
EA201491481A1 (ru) 2014-11-28
BR112014019504A2 (pt) 2017-06-27
CN104203277A (zh) 2014-12-10
IN2014MN01513A (https=) 2015-09-11
US10428124B2 (en) 2019-10-01
JP2015513527A (ja) 2015-05-14
US20150023992A1 (en) 2015-01-22
HK1204929A1 (en) 2015-12-11
EP2812026A4 (en) 2016-04-27
CA2864084A1 (en) 2013-08-15
EP2812026A1 (en) 2014-12-17
MX2014009285A (es) 2015-02-04
AU2013216993B2 (en) 2016-09-15
KR20140129124A (ko) 2014-11-06
WO2013119863A1 (en) 2013-08-15
AU2013216993A1 (en) 2014-08-21

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ TIMOTHY GRASS ALLERGENS AND METHODS AND USES FOR IMMUNE RESPONSE MODULATION

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ TIMOTHY GRASS ALLERGENS AND METHODS AND USES FOR IMMUNE RESPONSE MODULATION

TH Corrigenda

Free format text: IN VOL 28 , NO 32 , PAGE(S) 4294 UNDER THE HEADING AMENDMENTS - AMENDMENTS MADE DELETE ALL REFERENCES TO 2013216993

DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 22 SEP 2016

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 22 SEP 2016

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired