AU2013209958B2 - Pyran-spirocyclic piperidine amides as modulators of ion channels - Google Patents
Pyran-spirocyclic piperidine amides as modulators of ion channels Download PDFInfo
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- AU2013209958B2 AU2013209958B2 AU2013209958A AU2013209958A AU2013209958B2 AU 2013209958 B2 AU2013209958 B2 AU 2013209958B2 AU 2013209958 A AU2013209958 A AU 2013209958A AU 2013209958 A AU2013209958 A AU 2013209958A AU 2013209958 B2 AU2013209958 B2 AU 2013209958B2
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- pain
- compound
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- alkyl
- isopropoxy
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Classifications
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261586875P | 2012-01-16 | 2012-01-16 | |
| US61/586,875 | 2012-01-16 | ||
| PCT/US2013/021535 WO2013109521A1 (en) | 2012-01-16 | 2013-01-15 | Pyran-spirocyclic piperidine amides as modulators of ion channels |
Publications (2)
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| AU2013209958A1 AU2013209958A1 (en) | 2014-08-07 |
| AU2013209958B2 true AU2013209958B2 (en) | 2017-09-07 |
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| AU2013209958A Expired - Fee Related AU2013209958B2 (en) | 2012-01-16 | 2013-01-15 | Pyran-spirocyclic piperidine amides as modulators of ion channels |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9403839B2 (enExample) |
| EP (1) | EP2804868B1 (enExample) |
| JP (1) | JP6215230B2 (enExample) |
| CN (1) | CN104136442B (enExample) |
| AU (1) | AU2013209958B2 (enExample) |
| CA (1) | CA2863343A1 (enExample) |
| ES (1) | ES2631611T3 (enExample) |
| MX (1) | MX2014008591A (enExample) |
| NZ (1) | NZ627259A (enExample) |
| WO (1) | WO2013109521A1 (enExample) |
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| JP6337109B2 (ja) | 2013-07-19 | 2018-06-06 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | ナトリウムチャネルの調節剤としてのスルホンアミド |
| TWI703154B (zh) | 2013-12-13 | 2020-09-01 | 美商維泰克斯製藥公司 | 作為鈉通道調節劑之吡啶酮醯胺之前藥 |
| UA124857C2 (uk) | 2017-05-16 | 2021-12-01 | Вертекс Фармасьютикалз Інкорпорейтед | Дейтеровані піридонаміди і їх проліки як модулятори натрієвих каналів |
| UY37806A (es) | 2017-07-11 | 2020-01-31 | Vertex Pharma | Carboxamidas como moduladores de los canales de sodio |
| CA3081424A1 (en) * | 2017-11-01 | 2019-05-09 | Bristol-Myers Squibb Company | Spirocyclic compounds as farnesoid x receptor modulators |
| CN108276307A (zh) * | 2018-01-17 | 2018-07-13 | 常熟浸大科技有限公司 | 3-氰基-4-烃氧基苯甲酸酯的合成方法 |
| EP3752152A1 (en) | 2018-02-12 | 2020-12-23 | Vertex Pharmaceuticals Incorporated | A method of treating pain |
| CN111712494A (zh) | 2018-02-13 | 2020-09-25 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 |
| CN110156674A (zh) * | 2018-02-13 | 2019-08-23 | 中国科学院上海有机化学研究所 | 一种作为吲哚胺-2,3-双加氧酶抑制剂的螺环化合物 |
| EP4600247A3 (en) | 2018-04-19 | 2025-11-19 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| US11993581B2 (en) | 2018-07-09 | 2024-05-28 | Lieber Institue, Inc | Pyridazine compounds for inhibiting Nav1.8 |
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| ES2631611T3 (es) | 2017-09-01 |
| EP2804868A1 (en) | 2014-11-26 |
| HK1203074A1 (zh) | 2015-10-16 |
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| EP2804868B1 (en) | 2017-04-12 |
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| US9403839B2 (en) | 2016-08-02 |
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| CN104136442A (zh) | 2014-11-05 |
| CN104136442B (zh) | 2016-12-21 |
| JP2015505321A (ja) | 2015-02-19 |
| WO2013109521A1 (en) | 2013-07-25 |
| NZ627259A (en) | 2016-12-23 |
| US20150005304A1 (en) | 2015-01-01 |
| AU2013209958A1 (en) | 2014-08-07 |
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