AU2011305817B2 - Anti-SSX-2 T cell receptors and related materials and methods of use - Google Patents

Anti-SSX-2 T cell receptors and related materials and methods of use Download PDF

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AU2011305817B2
AU2011305817B2 AU2011305817A AU2011305817A AU2011305817B2 AU 2011305817 B2 AU2011305817 B2 AU 2011305817B2 AU 2011305817 A AU2011305817 A AU 2011305817A AU 2011305817 A AU2011305817 A AU 2011305817A AU 2011305817 B2 AU2011305817 B2 AU 2011305817B2
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tcr
ssx
seq
cancer
cells
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AU2011305817A1 (en
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Nachimuthu Chinnasamy
Richard A. Morgan
Steven A. Rosenberg
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US Department of Health and Human Services
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Proteomics, Peptides & Aminoacids (AREA)
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AU2011305817A 2010-09-21 2011-09-14 Anti-SSX-2 T cell receptors and related materials and methods of use Active AU2011305817B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38493110P 2010-09-21 2010-09-21
US61/384,931 2010-09-21
PCT/US2011/051537 WO2012040012A1 (en) 2010-09-21 2011-09-14 Anti-ssx-2 t cell receptors and related materials and methods of use

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AU2011305817A1 AU2011305817A1 (en) 2013-04-04
AU2011305817B2 true AU2011305817B2 (en) 2014-12-11

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EP (2) EP3533802B1 (cg-RX-API-DMAC7.html)
JP (2) JP6133209B2 (cg-RX-API-DMAC7.html)
CN (1) CN103124740B (cg-RX-API-DMAC7.html)
AU (1) AU2011305817B2 (cg-RX-API-DMAC7.html)
CA (1) CA2811788C (cg-RX-API-DMAC7.html)
ES (2) ES2876176T3 (cg-RX-API-DMAC7.html)
IL (3) IL225063A (cg-RX-API-DMAC7.html)
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