AU2011256264B2 - Method for purifying a fused pyrrolocarbazole derivative - Google Patents

Method for purifying a fused pyrrolocarbazole derivative Download PDF

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Publication number
AU2011256264B2
AU2011256264B2 AU2011256264A AU2011256264A AU2011256264B2 AU 2011256264 B2 AU2011256264 B2 AU 2011256264B2 AU 2011256264 A AU2011256264 A AU 2011256264A AU 2011256264 A AU2011256264 A AU 2011256264A AU 2011256264 B2 AU2011256264 B2 AU 2011256264B2
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AU
Australia
Prior art keywords
formula
compound
theta
degrees
acid complex
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AU2011256264A
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English (en)
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AU2011256264A1 (en
Inventor
Shawn P. Allwein
Arnaud Grandeury
Guy Piacenza
Sebastien Rose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Sante SAS
Cephalon LLC
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Teva Sante SAS
Cephalon LLC
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Publication of AU2011256264A1 publication Critical patent/AU2011256264A1/en
Assigned to CEPHALON, INC., TEVA SANTE reassignment CEPHALON, INC. Amend patent request/document other than specification (104) Assignors: CEPHALON FRANCE, CEPHALON, INC.
Application granted granted Critical
Publication of AU2011256264B2 publication Critical patent/AU2011256264B2/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2011256264A 2010-05-18 2011-05-17 Method for purifying a fused pyrrolocarbazole derivative Active AU2011256264B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34583110P 2010-05-18 2010-05-18
US61/345,831 2010-05-18
PCT/US2011/036814 WO2011146488A1 (en) 2010-05-18 2011-05-17 Method for purifying a fused pyrrolocarbazole derivative

Publications (2)

Publication Number Publication Date
AU2011256264A1 AU2011256264A1 (en) 2013-01-10
AU2011256264B2 true AU2011256264B2 (en) 2016-09-15

Family

ID=44168420

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011256264A Active AU2011256264B2 (en) 2010-05-18 2011-05-17 Method for purifying a fused pyrrolocarbazole derivative

Country Status (20)

Country Link
US (1) US8884014B2 (cg-RX-API-DMAC7.html)
EP (1) EP2571885B1 (cg-RX-API-DMAC7.html)
JP (2) JP5828594B2 (cg-RX-API-DMAC7.html)
KR (1) KR101815332B1 (cg-RX-API-DMAC7.html)
CN (1) CN102958934B (cg-RX-API-DMAC7.html)
AU (1) AU2011256264B2 (cg-RX-API-DMAC7.html)
BR (1) BR112012029374B1 (cg-RX-API-DMAC7.html)
CA (1) CA2799517C (cg-RX-API-DMAC7.html)
CL (1) CL2012003208A1 (cg-RX-API-DMAC7.html)
EA (1) EA021869B1 (cg-RX-API-DMAC7.html)
ES (1) ES2530015T3 (cg-RX-API-DMAC7.html)
IL (2) IL223016A0 (cg-RX-API-DMAC7.html)
MX (1) MX2012013304A (cg-RX-API-DMAC7.html)
MY (1) MY156830A (cg-RX-API-DMAC7.html)
NZ (1) NZ604135A (cg-RX-API-DMAC7.html)
PH (1) PH12012502250A1 (cg-RX-API-DMAC7.html)
SG (2) SG10201503541WA (cg-RX-API-DMAC7.html)
UA (1) UA108498C2 (cg-RX-API-DMAC7.html)
WO (1) WO2011146488A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201209305B (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2399588T3 (es) 2008-11-19 2013-04-02 Cephalon, Inc. Nuevas formas de un compuesto de indazolo[5,4-A]pirrolo[3,4-C]carbazol

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010059795A1 (en) * 2008-11-19 2010-05-27 Cephalon, Inc. Novel forms of an indazolo [5,4-a] pyrrolo [3,4-c] carbazole compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60103171T2 (de) * 2000-09-29 2004-11-11 Eli Lilly And Co., Indianapolis Verfahren und verbindungen zur behandlung proliferativer erkrankungen
US7169802B2 (en) 2003-12-23 2007-01-30 Cephalon, Inc. Fused pyrrolocarbazoles
JP2006241579A (ja) 2005-03-07 2006-09-14 Nippon Paint Co Ltd 化成処理剤及び表面処理金属

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010059795A1 (en) * 2008-11-19 2010-05-27 Cephalon, Inc. Novel forms of an indazolo [5,4-a] pyrrolo [3,4-c] carbazole compound

Also Published As

Publication number Publication date
ES2530015T3 (es) 2015-02-25
MX2012013304A (es) 2013-04-03
JP2016074668A (ja) 2016-05-12
US20130123499A1 (en) 2013-05-16
MY156830A (en) 2016-03-31
WO2011146488A1 (en) 2011-11-24
US8884014B2 (en) 2014-11-11
EP2571885B1 (en) 2014-11-12
SG10201503541WA (en) 2015-06-29
EP2571885A1 (en) 2013-03-27
KR20140095116A (ko) 2014-08-01
EA021869B1 (ru) 2015-09-30
BR112012029374A8 (pt) 2017-12-26
IL242221A0 (en) 2015-11-30
CL2012003208A1 (es) 2013-05-17
KR101815332B1 (ko) 2018-01-04
AU2011256264A1 (en) 2013-01-10
CN102958934A (zh) 2013-03-06
IL223016A0 (en) 2013-02-03
IL242221B (en) 2018-06-28
BR112012029374B1 (pt) 2021-05-25
CN102958934B (zh) 2015-06-17
CA2799517A1 (en) 2011-11-24
PH12012502250A1 (en) 2013-02-04
HK1182100A1 (en) 2013-11-22
CA2799517C (en) 2019-01-22
BR112012029374A2 (pt) 2016-07-26
JP5828594B2 (ja) 2015-12-09
NZ604135A (en) 2015-02-27
JP2013526573A (ja) 2013-06-24
EA201291269A1 (ru) 2013-05-30
UA108498C2 (en) 2015-05-12
SG185645A1 (en) 2012-12-28
ZA201209305B (en) 2014-02-26

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