AU2011254386B2 - Diagnostic methods - Google Patents

Diagnostic methods Download PDF

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Publication number
AU2011254386B2
AU2011254386B2 AU2011254386A AU2011254386A AU2011254386B2 AU 2011254386 B2 AU2011254386 B2 AU 2011254386B2 AU 2011254386 A AU2011254386 A AU 2011254386A AU 2011254386 A AU2011254386 A AU 2011254386A AU 2011254386 B2 AU2011254386 B2 AU 2011254386B2
Authority
AU
Australia
Prior art keywords
protein
human
sptr
uniprotkb
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2011254386A
Other languages
English (en)
Other versions
AU2011254386A1 (en
Inventor
Loic Gerard Dayon
Joan Montaner Villalonga
Jean-Charles Sanchez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Geneve
Fundacio Institut de Recerca Hospital Universitari Vall dHebron
Proteome Sciences PLC
Original Assignee
Universite de Geneve
Recerca Institut De Recerca Hospital Univ Vall Dhebron
Fundacio Institut de Recerca Hospital Universitari Vall dHebron
Electrophoretics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Geneve, Recerca Institut De Recerca Hospital Univ Vall Dhebron, Fundacio Institut de Recerca Hospital Universitari Vall dHebron, Electrophoretics Ltd filed Critical Universite de Geneve
Publication of AU2011254386A1 publication Critical patent/AU2011254386A1/en
Application granted granted Critical
Publication of AU2011254386B2 publication Critical patent/AU2011254386B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088—Glutathione transferase (2.5.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AU2011254386A 2010-05-21 2011-05-23 Diagnostic methods Ceased AU2011254386B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1008541.3 2010-05-21
GBGB1008541.3A GB201008541D0 (en) 2010-05-21 2010-05-21 Diagnostic methods
PCT/GB2011/000784 WO2011144914A2 (en) 2010-05-21 2011-05-23 Diagnostic methods

Publications (2)

Publication Number Publication Date
AU2011254386A1 AU2011254386A1 (en) 2012-12-06
AU2011254386B2 true AU2011254386B2 (en) 2017-01-12

Family

ID=42341144

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011254386A Ceased AU2011254386B2 (en) 2010-05-21 2011-05-23 Diagnostic methods

Country Status (7)

Country Link
US (1) US20130252834A1 (enExample)
EP (1) EP2572202A2 (enExample)
JP (1) JP5775568B2 (enExample)
AU (1) AU2011254386B2 (enExample)
CA (1) CA2800038A1 (enExample)
GB (1) GB201008541D0 (enExample)
WO (1) WO2011144914A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2628013B1 (en) * 2010-10-14 2019-06-12 The Johns Hopkins University Biomarkers of brain injury
EP2707389B1 (en) 2011-05-12 2019-10-30 The Johns Hopkins University Assay reagents for a neurogranin diagnostic kit
US20140377763A1 (en) * 2012-01-12 2014-12-25 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Brain damage marker
US9709573B2 (en) 2012-03-13 2017-07-18 The Johns Hopkins University Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration
WO2015009907A1 (en) 2013-07-17 2015-01-22 The Johns Hopkins University A multi-protein biomarker assay for brain injury detection and outcome
CN103432574B (zh) * 2013-08-25 2015-04-08 浙江大学 一种过氧化物酶在制备防治脑血管疾病药物中的应用
EP3570037B1 (en) * 2013-09-13 2024-10-09 The Board of Trustees of the Leland Stanford Junior University Multiplexed imaging of tissues using mass tags and secondary ion mass spectrometry
CN107003317B (zh) * 2014-10-06 2019-04-19 日内瓦大学 生物标记及其在脑损伤中的应用
WO2017174557A2 (en) 2016-04-04 2017-10-12 Brains Online Holding B.V. Use of push pull microdialysis in combination with shotgun proteomics for analyzing the proteome in extracellular space of brain
CA3052636A1 (en) * 2017-02-07 2018-08-16 Bioregency, Inc. S100.beta. and isoforms for detection of neurological conditions
CN107748263A (zh) * 2017-08-31 2018-03-02 北京臻惠康生物科技有限公司 一种纤维蛋白溶酶原的新用途及试剂盒
CN109536469B (zh) * 2018-11-23 2021-02-09 北华大学 突变改造Prx6蛋白及其表达基因、制备方法和应用
WO2021163608A2 (en) * 2020-02-14 2021-08-19 Galaxy Ccro, Inc. Devices and methods for treating ischaemia and acute respiratory distress syndromes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105417A2 (en) * 2005-03-31 2006-10-05 Dana-Farber Cancer Institute, Inc. Compositions and methods for the identification, assessment, prevention, and therapy of neurological diseases, disorders and conditions
WO2007007129A2 (en) * 2005-07-14 2007-01-18 Universite De Geneve Diagnostic method for brain damage-related disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
CA2263063C (en) * 1999-02-26 2004-08-10 Skye Pharmatech Incorporated Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
EP1664795B1 (en) * 2003-09-20 2017-11-08 Electrophoretics Limited Diagnostic method for brain damage-related disorders
JP4521512B2 (ja) * 2005-06-15 2010-08-11 独立行政法人産業技術総合研究所 痴呆症の診断方法及び診断キット
JP5244103B2 (ja) * 2006-08-09 2013-07-24 ホームステッド クリニカル コーポレイション 器官特異的蛋白質およびその使用方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105417A2 (en) * 2005-03-31 2006-10-05 Dana-Farber Cancer Institute, Inc. Compositions and methods for the identification, assessment, prevention, and therapy of neurological diseases, disorders and conditions
WO2007007129A2 (en) * 2005-07-14 2007-01-18 Universite De Geneve Diagnostic method for brain damage-related disorders

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dayon et al., Relative Quantification of Proteins in Human Cerebrospinal Fluids by MS/MS Using 6-Plex Isobaric Tags, Analytical Chem., 80(8), 2921-2931 *

Also Published As

Publication number Publication date
JP2013531784A (ja) 2013-08-08
CA2800038A1 (en) 2011-11-24
JP5775568B2 (ja) 2015-09-09
EP2572202A2 (en) 2013-03-27
WO2011144914A3 (en) 2012-03-29
US20130252834A1 (en) 2013-09-26
GB201008541D0 (en) 2010-07-07
WO2011144914A2 (en) 2011-11-24
AU2011254386A1 (en) 2012-12-06

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired