AU2011214124B2 - Process for providing a filled canister for an inhaler - Google Patents
Process for providing a filled canister for an inhaler Download PDFInfo
- Publication number
- AU2011214124B2 AU2011214124B2 AU2011214124A AU2011214124A AU2011214124B2 AU 2011214124 B2 AU2011214124 B2 AU 2011214124B2 AU 2011214124 A AU2011214124 A AU 2011214124A AU 2011214124 A AU2011214124 A AU 2011214124A AU 2011214124 B2 AU2011214124 B2 AU 2011214124B2
- Authority
- AU
- Australia
- Prior art keywords
- canister
- medicament
- filled
- air
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000000034 method Methods 0.000 title claims abstract description 61
- 230000008569 process Effects 0.000 title claims abstract description 53
- 239000003814 drug Substances 0.000 claims abstract description 88
- 239000003380 propellant Substances 0.000 claims abstract description 57
- 238000011049 filling Methods 0.000 claims abstract description 48
- 239000007788 liquid Substances 0.000 claims abstract description 22
- 238000007789 sealing Methods 0.000 claims abstract description 19
- -1 hydroxy-phenyl-methyl Chemical group 0.000 claims description 20
- 150000003839 salts Chemical class 0.000 claims description 14
- 239000004480 active ingredient Substances 0.000 claims description 10
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 9
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 7
- LBLYYCQCTBFVLH-UHFFFAOYSA-M 2-methylbenzenesulfonate Chemical compound CC1=CC=CC=C1S([O-])(=O)=O LBLYYCQCTBFVLH-UHFFFAOYSA-M 0.000 claims description 6
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 6
- QZZUEBNBZAPZLX-QFIPXVFZSA-N indacaterol Chemical compound N1C(=O)C=CC2=C1C(O)=CC=C2[C@@H](O)CNC1CC(C=C(C(=C2)CC)CC)=C2C1 QZZUEBNBZAPZLX-QFIPXVFZSA-N 0.000 claims description 6
- 229960004078 indacaterol Drugs 0.000 claims description 5
- YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 claims description 4
- LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical compound FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 claims description 4
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 claims description 4
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 4
- FNYFFCOCVNTJCD-NNMXADRKSA-N [(3r)-1-[2-(4-fluorophenyl)ethyl]-1-azoniabicyclo[2.2.2]octan-3-yl] (2s)-2-phenyl-2-piperidin-1-ylpropanoate Chemical class N1([C@](C)(C(=O)O[C@@H]2C3CC[N+](CC3)(CCC=3C=CC(F)=CC=3)C2)C=2C=CC=CC=2)CCCCC1 FNYFFCOCVNTJCD-NNMXADRKSA-N 0.000 claims description 4
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 claims description 4
- 229960004436 budesonide Drugs 0.000 claims description 4
- 239000006184 cosolvent Substances 0.000 claims description 4
- 229960002052 salbutamol Drugs 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- XWTYSIMOBUGWOL-UHFFFAOYSA-N (+-)-Terbutaline Chemical compound CC(C)(C)NCC(O)C1=CC(O)=CC(O)=C1 XWTYSIMOBUGWOL-UHFFFAOYSA-N 0.000 claims description 3
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 claims description 3
- 229960005012 aclidinium bromide Drugs 0.000 claims description 3
- 229950000210 beclometasone dipropionate Drugs 0.000 claims description 3
- 229960000289 fluticasone propionate Drugs 0.000 claims description 3
- WMWTYOKRWGGJOA-CENSZEJFSA-N fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 claims description 3
- 229910021653 sulphate ion Inorganic materials 0.000 claims description 3
- 229960000195 terbutaline Drugs 0.000 claims description 3
- RATSWNOMCHFQGJ-TUYNVFRMSA-N (e)-but-2-enedioic acid;n-[2-hydroxy-5-[(1s)-1-hydroxy-2-[[(2s)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide;dihydrate Chemical compound O.O.OC(=O)\C=C\C(O)=O.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1 RATSWNOMCHFQGJ-TUYNVFRMSA-N 0.000 claims description 2
- FIDWUJWRKJJJLL-UHFFFAOYSA-N 3-[2-(4-hydroxy-2-oxo-3h-1,3-benzothiazol-7-yl)ethylamino]-n-[2-[2-(4-methylphenyl)ethoxy]ethyl]propane-1-sulfonamide Chemical compound C1=CC(C)=CC=C1CCOCCNS(=O)(=O)CCCNCCC1=CC=C(O)C2=C1SC(=O)N2 FIDWUJWRKJJJLL-UHFFFAOYSA-N 0.000 claims description 2
- LSLYOANBFKQKPT-DIFFPNOSSA-N 5-[(1r)-1-hydroxy-2-[[(2r)-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]benzene-1,3-diol Chemical compound C([C@@H](C)NC[C@H](O)C=1C=C(O)C=C(O)C=1)C1=CC=C(O)C=C1 LSLYOANBFKQKPT-DIFFPNOSSA-N 0.000 claims description 2
- XLAKJQPTOJHYDR-QTQXQZBYSA-M aclidinium bromide Chemical compound [Br-].C([C@@H](C(CC1)CC2)OC(=O)C(O)(C=3SC=CC=3)C=3SC=CC=3)[N+]21CCCOC1=CC=CC=C1 XLAKJQPTOJHYDR-QTQXQZBYSA-M 0.000 claims description 2
- 229960001117 clenbuterol Drugs 0.000 claims description 2
- STJMRWALKKWQGH-UHFFFAOYSA-N clenbuterol Chemical compound CC(C)(C)NCC(O)C1=CC(Cl)=C(N)C(Cl)=C1 STJMRWALKKWQGH-UHFFFAOYSA-N 0.000 claims description 2
- 229960000265 cromoglicic acid Drugs 0.000 claims description 2
- VLARUOGDXDTHEH-UHFFFAOYSA-L disodium cromoglycate Chemical compound [Na+].[Na+].O1C(C([O-])=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C([O-])=O)O2 VLARUOGDXDTHEH-UHFFFAOYSA-L 0.000 claims description 2
- 229960001022 fenoterol Drugs 0.000 claims description 2
- 229960000676 flunisolide Drugs 0.000 claims description 2
- 229960003610 formoterol fumarate dihydrate Drugs 0.000 claims description 2
- 229960001361 ipratropium bromide Drugs 0.000 claims description 2
- KEWHKYJURDBRMN-ZEODDXGYSA-M ipratropium bromide hydrate Chemical compound O.[Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 KEWHKYJURDBRMN-ZEODDXGYSA-M 0.000 claims description 2
- 239000000314 lubricant Substances 0.000 claims description 2
- 229960001664 mometasone Drugs 0.000 claims description 2
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 claims description 2
- XTEGVFVZDVNBPF-UHFFFAOYSA-L naphthalene-1,5-disulfonate(2-) Chemical compound C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1S([O-])(=O)=O XTEGVFVZDVNBPF-UHFFFAOYSA-L 0.000 claims description 2
- RQTOOFIXOKYGAN-UHFFFAOYSA-N nedocromil Chemical compound CCN1C(C(O)=O)=CC(=O)C2=C1C(CCC)=C1OC(C(O)=O)=CC(=O)C1=C2 RQTOOFIXOKYGAN-UHFFFAOYSA-N 0.000 claims description 2
- 229960004398 nedocromil Drugs 0.000 claims description 2
- MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 claims description 2
- 229960002720 reproterol Drugs 0.000 claims description 2
- WVLAAKXASPCBGT-UHFFFAOYSA-N reproterol Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CCCNCC(O)C1=CC(O)=CC(O)=C1 WVLAAKXASPCBGT-UHFFFAOYSA-N 0.000 claims description 2
- IXTCZMJQGGONPY-XJAYAHQCSA-N rofleponide Chemical compound C1([C@@H](F)C2)=CC(=O)CC[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3O[C@@H](CCC)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O IXTCZMJQGGONPY-XJAYAHQCSA-N 0.000 claims description 2
- 229950004432 rofleponide Drugs 0.000 claims description 2
- KFVSLSTULZVNPG-UHFFFAOYSA-N terbutaline sulfate Chemical compound [O-]S([O-])(=O)=O.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1 KFVSLSTULZVNPG-UHFFFAOYSA-N 0.000 claims description 2
- 229940110309 tiotropium Drugs 0.000 claims description 2
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- ZMANZCXQSJIPKH-UHFFFAOYSA-N triethylamine Natural products CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 claims 1
- 238000010926 purge Methods 0.000 abstract description 19
- 229940071648 metered dose inhaler Drugs 0.000 abstract description 6
- 239000000306 component Substances 0.000 description 17
- 238000005429 filling process Methods 0.000 description 17
- 239000000126 substance Substances 0.000 description 17
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- 238000002156 mixing Methods 0.000 description 6
- 239000012141 concentrate Substances 0.000 description 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 5
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 5
- 239000000556 agonist Substances 0.000 description 4
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
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- XMQODGUTLZXUGZ-RPBOFIJWSA-N 2-[(3s)-3-[[1-[(2r)-2-ethoxycarbonyl-4-phenylbutyl]cyclopentanecarbonyl]amino]-2-oxo-4,5-dihydro-3h-1-benzazepin-1-yl]acetic acid Chemical compound C([C@@H](C(=O)OCC)CC1(CCCC1)C(=O)N[C@@H]1C(N(CC(O)=O)C2=CC=CC=C2CC1)=O)CC1=CC=CC=C1 XMQODGUTLZXUGZ-RPBOFIJWSA-N 0.000 description 3
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 description 3
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 3
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- STTGOFBGRUQUOE-NDEPHWFRSA-N 2-[(4-chlorophenyl)methoxy]ethyl-[[2-[(r)-cyclohexyl-hydroxy-phenylmethyl]-1,3-oxazol-5-yl]methyl]-dimethylazanium Chemical class C=1N=C([C@@](O)(C2CCCCC2)C=2C=CC=CC=2)OC=1C[N+](C)(C)CCOCC1=CC=C(Cl)C=C1 STTGOFBGRUQUOE-NDEPHWFRSA-N 0.000 description 2
- AXUZQJFHDNNPFG-LHAVAQOQSA-N 3-[(r)-[3-[(e)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoic acid Chemical compound CN(C)C(=O)CCS[C@H](SCCC(O)=O)C1=CC=CC(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)=C1 AXUZQJFHDNNPFG-LHAVAQOQSA-N 0.000 description 2
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Classifications
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- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
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- B65B37/00—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
- B65B37/06—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged by pistons or pumps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Vacuum Packaging (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Basic Packing Technique (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015200276A AU2015200276B2 (en) | 2010-02-10 | 2015-01-21 | A filled canister for an inhaler |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30298810P | 2010-02-10 | 2010-02-10 | |
| US61/302,988 | 2010-02-10 | ||
| PCT/GB2011/050222 WO2011098798A1 (en) | 2010-02-10 | 2011-02-09 | Process for providing a filled canister for an inhaler |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015200276A Division AU2015200276B2 (en) | 2010-02-10 | 2015-01-21 | A filled canister for an inhaler |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2011214124A1 AU2011214124A1 (en) | 2012-08-30 |
| AU2011214124B2 true AU2011214124B2 (en) | 2014-10-30 |
Family
ID=43971143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2011214124A Ceased AU2011214124B2 (en) | 2010-02-10 | 2011-02-09 | Process for providing a filled canister for an inhaler |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20130112194A1 (https=) |
| EP (1) | EP2534054A1 (https=) |
| JP (1) | JP2013519413A (https=) |
| KR (1) | KR20130004266A (https=) |
| CN (1) | CN102858640B (https=) |
| AR (1) | AR080159A1 (https=) |
| AU (1) | AU2011214124B2 (https=) |
| BR (1) | BR112012019878A2 (https=) |
| CA (1) | CA2788015A1 (https=) |
| MX (1) | MX2012008906A (https=) |
| NZ (2) | NZ601454A (https=) |
| RU (1) | RU2562017C2 (https=) |
| WO (1) | WO2011098798A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201118188D0 (en) * | 2011-10-21 | 2011-12-07 | 3M Innovative Properties Co | Manufacture of medicinal aerosol canisters |
| EP2819669B1 (de) * | 2012-02-28 | 2021-04-21 | Boehringer Ingelheim International GmbH | Neue treibgashaltige tiotropium-formulierung |
| GB201402513D0 (en) | 2014-02-13 | 2014-04-02 | Cardiff Scintigraphics Ltd | Pressurised metered dose inhalers and method of manufacture |
| EP3021033B1 (de) * | 2014-11-12 | 2019-04-24 | CleanTech Swiss AG | Abfüllstation für Gasflaschen nebst Abfüllverfahren |
| GB2554857A (en) * | 2016-09-29 | 2018-04-18 | Mexichem Fluor Sa De Cv | A propellant filling apparatus |
| GB2561898A (en) * | 2017-04-28 | 2018-10-31 | Mexichem Fluor Sa De Cv | Improvements in or relating to propellant conditioning assemblies |
| GB2584686A (en) * | 2019-06-11 | 2020-12-16 | Mexichem Fluor Sa De Cv | Methods |
| IT202200002657A1 (it) * | 2022-02-14 | 2023-08-14 | Mox Lab S R L | Sistema di ricarica perfezionato portatile da banco per bombolette bag-on-valve pressurizzate con aria compressa. |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004020289A1 (en) * | 2002-08-27 | 2004-03-11 | Schering Corporation | Process for producing metered dose inhaler formulations |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU286738A1 (ru) * | 1970-01-05 | 1976-08-25 | Специальное Конструкторское Бюро Химизации Народного Хозяйства Латвийской Сср | Устройство дл заполнени пропеллнтом аэрозольного сосуда |
| US4271875A (en) * | 1978-09-21 | 1981-06-09 | Philip Meshberg | Dispenser adapted for fast pressure filling |
| US5143260A (en) * | 1990-06-05 | 1992-09-01 | Nozone Dispenser Systems, Inc. | Aerosol adapter clamp and power system |
| EP1259429A2 (en) * | 2000-03-01 | 2002-11-27 | Glaxo Group Limited | Metered dose inhaler |
| US6637430B1 (en) * | 2000-06-16 | 2003-10-28 | Ponwell Enterprises Limited | Respiratory delivery system with power/medicament recharge assembly |
| WO2002024552A2 (en) * | 2000-09-18 | 2002-03-28 | Glaxo Group Limited | Coated can for a metered dose inhaler |
| FR2814200B1 (fr) * | 2000-09-21 | 2005-08-05 | Marwal Systems | Dispositif de puisage et de jaugeage pour reservoir de carburant de vehicule automobile |
| GB0125380D0 (en) * | 2001-10-23 | 2001-12-12 | Glaxo Group Ltd | Medicament dispenser |
| SE0104251D0 (sv) | 2001-12-14 | 2001-12-14 | Astrazeneca Ab | Novel compounds |
| US20050121025A1 (en) * | 2003-12-04 | 2005-06-09 | Gamard Stephan C.F. | Portable gas operating inhaler |
| DE10361735A1 (de) * | 2003-12-29 | 2005-07-28 | Boehringer Ingelheim International Gmbh | Vorrichtung zum Ausbringen eins inhalierfähigen Aerosols mit Teilchen niedriger Anfangsgeschwindigkeit |
| EP1595531A1 (en) * | 2004-05-13 | 2005-11-16 | CHIESI FARMACEUTICI S.p.A. | Stable pharmaceutical solution formulations for pressurized metered dose inhalers |
| SE0401773D0 (sv) * | 2004-07-02 | 2004-07-02 | Astrazeneca Ab | An inhalation and a method for assemnling said inhalation device |
| USH2205H1 (en) * | 2004-07-22 | 2007-11-06 | Andersen Jason D | Method and apparatus for purging a propellant from a filling head during the filling of an aerosol container |
| US7605168B2 (en) | 2004-09-03 | 2009-10-20 | Plexxikon, Inc. | PDE4B inhibitors |
| KR20080035604A (ko) * | 2005-08-08 | 2008-04-23 | 노파르티스 아게 | 계량 흡입기용 단열식 캐니스터 |
| GB0518355D0 (en) * | 2005-09-08 | 2005-10-19 | Glaxo Group Ltd | An inhaler |
| BRPI0714463A2 (pt) | 2006-07-19 | 2013-04-02 | Astrazeneca Ab | compostos de espiropiperidina tricÍclicos, sua sÍntese e seus usos como moduladores de atividade receptora de quimiocina |
| US8225790B2 (en) * | 2007-01-02 | 2012-07-24 | Astrazeneca Ab | Inhaler 624 |
-
2011
- 2011-02-09 NZ NZ601454A patent/NZ601454A/en not_active IP Right Cessation
- 2011-02-09 JP JP2012552468A patent/JP2013519413A/ja not_active Ceased
- 2011-02-09 KR KR1020127020892A patent/KR20130004266A/ko not_active Ceased
- 2011-02-09 CA CA2788015A patent/CA2788015A1/en not_active Abandoned
- 2011-02-09 CN CN201180018359.6A patent/CN102858640B/zh not_active Expired - Fee Related
- 2011-02-09 EP EP11707695A patent/EP2534054A1/en not_active Withdrawn
- 2011-02-09 RU RU2012135067/13A patent/RU2562017C2/ru not_active IP Right Cessation
- 2011-02-09 US US13/577,766 patent/US20130112194A1/en not_active Abandoned
- 2011-02-09 NZ NZ625734A patent/NZ625734A/en not_active IP Right Cessation
- 2011-02-09 BR BR112012019878A patent/BR112012019878A2/pt not_active IP Right Cessation
- 2011-02-09 MX MX2012008906A patent/MX2012008906A/es active IP Right Grant
- 2011-02-09 AU AU2011214124A patent/AU2011214124B2/en not_active Ceased
- 2011-02-09 WO PCT/GB2011/050222 patent/WO2011098798A1/en not_active Ceased
- 2011-02-10 AR ARP110100417A patent/AR080159A1/es unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004020289A1 (en) * | 2002-08-27 | 2004-03-11 | Schering Corporation | Process for producing metered dose inhaler formulations |
| US20080066744A1 (en) * | 2002-08-27 | 2008-03-20 | Schering Corporation | Process for producing metered dose inhaler formulations |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102858640A (zh) | 2013-01-02 |
| CA2788015A1 (en) | 2011-08-18 |
| JP2013519413A (ja) | 2013-05-30 |
| RU2012135067A (ru) | 2014-03-20 |
| WO2011098798A1 (en) | 2011-08-18 |
| RU2562017C2 (ru) | 2015-09-10 |
| AU2011214124A1 (en) | 2012-08-30 |
| CN102858640B (zh) | 2015-12-09 |
| MX2012008906A (es) | 2012-08-15 |
| NZ601454A (en) | 2014-06-27 |
| KR20130004266A (ko) | 2013-01-09 |
| AR080159A1 (es) | 2012-03-21 |
| US20130112194A1 (en) | 2013-05-09 |
| BR112012019878A2 (pt) | 2017-10-10 |
| EP2534054A1 (en) | 2012-12-19 |
| NZ625734A (en) | 2015-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |