AU2010291502B2 - Components for threading of bone - Google Patents
Components for threading of bone Download PDFInfo
- Publication number
- AU2010291502B2 AU2010291502B2 AU2010291502A AU2010291502A AU2010291502B2 AU 2010291502 B2 AU2010291502 B2 AU 2010291502B2 AU 2010291502 A AU2010291502 A AU 2010291502A AU 2010291502 A AU2010291502 A AU 2010291502A AU 2010291502 B2 AU2010291502 B2 AU 2010291502B2
- Authority
- AU
- Australia
- Prior art keywords
- thread
- implant
- thread forming
- section
- apical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0089—Implanting tools or instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
- A61B17/1655—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans for tapping
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/08—Machine parts specially adapted for dentistry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C3/00—Dental tools or instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C3/00—Dental tools or instruments
- A61C3/02—Tooth drilling or cutting instruments; Instruments acting like a sandblast machine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0022—Self-screwing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/08—Machine parts specially adapted for dentistry
- A61C1/082—Positioning or guiding, e.g. of drills
- A61C1/084—Positioning or guiding, e.g. of drills of implanting tools
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dentistry (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09011435.6A EP2292176B1 (en) | 2009-09-07 | 2009-09-07 | Implantation set |
| EP09011435.6 | 2009-09-07 | ||
| PCT/EP2010/005449 WO2011026644A2 (en) | 2009-09-07 | 2010-09-06 | Components for threading of bone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2010291502A1 AU2010291502A1 (en) | 2012-03-29 |
| AU2010291502B2 true AU2010291502B2 (en) | 2015-09-03 |
Family
ID=41651534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2010291502A Active AU2010291502B2 (en) | 2009-09-07 | 2010-09-06 | Components for threading of bone |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9259299B2 (enExample) |
| EP (1) | EP2292176B1 (enExample) |
| JP (1) | JP5883385B2 (enExample) |
| KR (1) | KR101745519B1 (enExample) |
| CN (1) | CN102481180B (enExample) |
| AU (1) | AU2010291502B2 (enExample) |
| BR (1) | BR112012005076B1 (enExample) |
| ES (1) | ES2710179T3 (enExample) |
| WO (1) | WO2011026644A2 (enExample) |
| ZA (1) | ZA201201362B (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2749684C (en) | 2009-01-16 | 2016-04-26 | Carbofix Orthopedics Ltd. | Composite material bone implant |
| ES2596828T3 (es) | 2009-09-07 | 2017-01-12 | Nobel Biocare Services Ag | Componentes para el roscado guiado de un hueso |
| CN105167830B (zh) | 2010-06-07 | 2018-06-12 | 卡波菲克斯整形有限公司 | 复合材料骨植入物 |
| US10154867B2 (en) | 2010-06-07 | 2018-12-18 | Carbofix In Orthopedics Llc | Multi-layer composite material bone screw |
| EP2510898A1 (en) | 2011-04-14 | 2012-10-17 | Astra Tech AB | Fixture |
| EP2510899A1 (en) | 2011-04-14 | 2012-10-17 | Astra Tech AB | Fixture |
| EP2510901A1 (en) * | 2011-04-14 | 2012-10-17 | Astra Tech AB | Set of fixtures |
| EP2510900A1 (en) | 2011-04-14 | 2012-10-17 | Astra Tech AB | Fixture |
| AU2012241850B2 (en) * | 2011-04-14 | 2016-02-25 | Dentsply Ih Ab | A fixture and a fixture set |
| US9526549B2 (en) | 2012-01-16 | 2016-12-27 | Carbofix Orthopedics Ltd. | Bone screw with insert |
| GB2509136A (en) | 2012-12-21 | 2014-06-25 | Nobel Biocare Services Ag | Dental component with metal adapter |
| GB2509135A (en) | 2012-12-21 | 2014-06-25 | Nobel Biocare Services Ag | An abutment with conical metal adapter |
| GB2509138A (en) | 2012-12-21 | 2014-06-25 | Nobel Biocare Services Ag | Dental component with screw fixation |
| RU2723130C2 (ru) | 2013-04-05 | 2020-06-08 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы и композиции для встраивания экзогенной последовательности в геном растений |
| WO2015066636A2 (en) | 2013-11-04 | 2015-05-07 | Dow Agrosciences Llc | Optimal maize loci |
| CN107223156A (zh) | 2013-11-04 | 2017-09-29 | 美国陶氏益农公司 | 最优玉米座位 |
| NZ735257A (en) | 2013-11-04 | 2018-09-28 | Dow Agrosciences Llc | Optimal soybean loci |
| DE102014019720B4 (de) * | 2014-03-24 | 2016-06-09 | Gernot Teichmann | Werkzeug zur Einbringung einer helikalen Kavität in einen Knochen |
| DE102014004132B4 (de) * | 2014-03-24 | 2016-01-28 | Gernot Teichmann | Werkzeug zur Einbringung einer helikalen Kavität in einen Knochen |
| DE102015100946B4 (de) * | 2015-01-22 | 2021-01-07 | Expi-Dent Gmbh | Dentalinstrument zur Präparation von Zähnen, insbesondere Zahnwurzelkanälen und Stift zum Einsatz in ein vorgesehenes Bohrloch, insbesondere ein mit einem erfindungsgemäßen Dentalinstrument erzeugtes Bohrloch |
| US10136902B2 (en) * | 2015-07-31 | 2018-11-27 | Warsaw Orthopedic, Inc. | Surgical instrument and method |
| US10617458B2 (en) | 2015-12-23 | 2020-04-14 | Carbofix In Orthopedics Llc | Multi-layer composite material bone screw |
| US11045287B2 (en) | 2016-01-29 | 2021-06-29 | Nobel Biocare Services Ag | Dentistry tool |
| CN105748169A (zh) * | 2016-04-22 | 2016-07-13 | 吴大怡 | 针孔骨挤扩器 |
| GB201708662D0 (en) | 2017-05-31 | 2017-07-12 | Tropic Biosciences Uk Ltd | Compositions and methods for increasing shelf-life of banana |
| GB201708665D0 (en) | 2017-05-31 | 2017-07-12 | Tropic Biosciences Uk Ltd | Compositions and methods for increasing extractability of solids from coffee beans |
| WO2018220582A1 (en) | 2017-05-31 | 2018-12-06 | Tropic Biosciences UK Limited | Methods of selecting cells comprising genome editing events |
| CN120193018A (zh) | 2017-09-19 | 2025-06-24 | 热带生物科学英国有限公司 | 修饰在真核细胞中用于沉默基因表达的非编码rna分子的特异性的方法 |
| KR101841747B1 (ko) * | 2017-12-22 | 2018-03-23 | 왕제원 | 임플란트용 픽스쳐 식립을 위한 방향확인 핀과 가이드 탭 드릴 키트 |
| GB201807192D0 (en) | 2018-05-01 | 2018-06-13 | Tropic Biosciences Uk Ltd | Compositions and methods for reducing caffeine content in coffee beans |
| EP3802839A1 (en) | 2018-06-07 | 2021-04-14 | The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) | Nucleic acid constructs and methods of using same |
| CN112384063A (zh) | 2018-06-07 | 2021-02-19 | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 再生及转殖大麻的方法 |
| EP4302723A3 (en) * | 2018-10-11 | 2024-04-10 | Straumann Holding AG | Dental implant thread |
| GB201903520D0 (en) | 2019-03-14 | 2019-05-01 | Tropic Biosciences Uk Ltd | Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells |
| GB201903521D0 (en) | 2019-03-14 | 2019-05-01 | Tropic Biosciences Uk Ltd | No title |
| GB201903519D0 (en) | 2019-03-14 | 2019-05-01 | Tropic Biosciences Uk Ltd | Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest |
| US11497609B2 (en) | 2019-04-26 | 2022-11-15 | Warsaw Orthopedic, Inc. | Retention system and method |
| GB202103256D0 (en) | 2021-03-09 | 2021-04-21 | Tropic Biosciences Uk Ltd | Method for silencing genes |
| GB202109586D0 (en) | 2021-07-02 | 2021-08-18 | Tropic Biosciences Uk Ltd | Method for editing banana genes |
| EP4362662A1 (en) | 2021-07-02 | 2024-05-08 | Tropic Biosciences UK Limited | Delay or prevention of browning in banana fruit |
| GB202112866D0 (en) | 2021-09-09 | 2021-10-27 | Tropic Biosciences Uk Ltd | Resistance to fusarium wilt in a banana |
| GB202112865D0 (en) | 2021-09-09 | 2021-10-27 | Tropic Biosciences Uk Ltd | Resistance to black sigatoka disease in banana |
| TWI772178B (zh) * | 2021-09-10 | 2022-07-21 | 陳俊龍 | 單次鑽鑿的整套植入組件 |
| GB202305021D0 (en) | 2023-04-04 | 2023-05-17 | Tropic Biosciences Uk Ltd | Methods for generating breaks in a genome |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2744564A1 (de) * | 1977-10-04 | 1979-04-05 | Schmidt Rimpler Reimar Dr | Werkzeugkombination zur einsetzung von zahnimplataten |
| US5593410A (en) * | 1989-10-26 | 1997-01-14 | Vrespa; Giuseppe | Screw device for fixing prostheses to bones |
| US5643269A (en) * | 1990-08-24 | 1997-07-01 | Haerle; Anton | Externally threaded bodies for use as taps or screws |
| US20060079894A1 (en) * | 2003-10-21 | 2006-04-13 | Innovative Spinal Technologies | Connector transfer tool for internal structure stabilization systems |
| US20090136898A1 (en) * | 2007-11-26 | 2009-05-28 | Kim Soo Hong | Tap Drill for Dental Implant |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4854873A (en) * | 1987-10-13 | 1989-08-08 | Hall Surgical Division Of Zimmer, Inc. | Oral implant |
| CA2130083A1 (en) * | 1992-02-14 | 1993-08-19 | Acufex Microsurgical, Inc. | Polymeric screws and coatings for surgical uses |
| ATE185062T1 (de) | 1993-02-10 | 1999-10-15 | Sulzer Spine Tech Inc | Werkzeugsatz zur stabilisierung der wirbelsäule |
| SE507337C2 (sv) | 1994-02-14 | 1998-05-18 | Nobel Biocare Ab | Anordning vid djupmarkeringssystem vid implantatshål i käkben |
| FR2735008A1 (fr) * | 1995-06-07 | 1996-12-13 | Jbs Sa | Ensemble pour preparation d'arthrodese intervertebrale |
| SE506596C2 (sv) | 1996-05-17 | 1998-01-19 | Nobel Biocare Ab | Självgängande förankringselement för iskruvning i tandben |
| US6569188B2 (en) * | 1996-08-05 | 2003-05-27 | Arthrex, Inc. | Hex drive bioabsorbable tissue anchor |
| US5865847A (en) | 1997-03-06 | 1999-02-02 | Sulzer Spine-Tech Inc. | Lordotic spinal implant |
| US6086595A (en) | 1997-08-29 | 2000-07-11 | Sulzer Spine-Tech Inc. | Apparatus and method for spinal stabilization |
| SE514142C2 (sv) | 1999-03-09 | 2001-01-08 | Nobel Biocare Ab | Självgängande implantat |
| US6283966B1 (en) | 1999-07-07 | 2001-09-04 | Sulzer Spine-Tech Inc. | Spinal surgery tools and positioning method |
| SE522958C2 (sv) | 2000-12-29 | 2004-03-16 | Nobel Biocare Ab | Förfarande, arrangemang (anordning) och program vid eller för protetisk installation |
| US6929647B2 (en) | 2001-02-21 | 2005-08-16 | Howmedica Osteonics Corp. | Instrumentation and method for implant insertion |
| US6540753B2 (en) | 2001-03-23 | 2003-04-01 | Howmedica Osteonics Corp. | Instrumentation for implant insertion |
| US6863529B2 (en) | 2001-05-18 | 2005-03-08 | Biohorizons Implant Systems, Inc. | Dental drill system and method of use |
| SE520765C2 (sv) | 2001-12-28 | 2003-08-19 | Nobel Biocare Ab | Anordning och arrangemang för att medelst mall ta upp hål till implantat i ben, företrädesvis käkben |
| FR2836372B1 (fr) | 2002-02-28 | 2004-06-04 | Obl | Procede et dispositif pour la mise en place d'implants dentaires |
| JP4420423B2 (ja) | 2002-09-26 | 2010-02-24 | 株式会社ジーシー | セルフタップ付き歯科用スクリュー型インプラントフィクスチャー用ドリルセット |
| SE526666C2 (sv) | 2002-12-30 | 2005-10-25 | Nobel Biocare Ab | Anordning och arrangemang för fixturinstallation |
| SE526665C2 (sv) | 2002-12-30 | 2005-10-25 | Nobel Biocare Ab | Anordning vid dentalt fastskruvningsarrangemang |
| IL156033A0 (en) | 2003-05-21 | 2004-03-28 | Ophir Fromovich Ophir Fromovic | Dental implant |
| CN100553577C (zh) | 2003-06-20 | 2009-10-28 | 精密医疗责任有限公司 | 用于在手术中对接骨板攻螺纹的系统 |
| US7241144B2 (en) | 2003-07-30 | 2007-07-10 | Bio-Lok International, Inc. | Method of bone expansion and compression for receiving a dental implant using threaded expanders |
| SE526223C2 (sv) | 2003-12-10 | 2005-08-02 | Nobel Biocare Ab | System och anordning vid framställning och isättning av tandbrouppbyggnad |
| SE526908C2 (sv) | 2003-12-22 | 2005-11-15 | Nobel Biocare Ab | Arrangemang för lägesorientering av brygga eller bro till dentala implantat |
| DE602004024588D1 (de) | 2004-02-05 | 2010-01-21 | Bti I & D | Geräte zur extraktion und sammlung von gewebepartikeln bei kühlungsloser bohrmethode mit niedriger drehgeschwindigkeit |
| SE527503C2 (sv) | 2004-08-05 | 2006-03-21 | Nobel Biocare Ab | Anordning och förfarande för att underlätta applicering till rätt läge av tand- eller tandrestmall |
| SE527504C2 (sv) | 2004-08-05 | 2006-03-21 | Nobel Biocare Ab | Styranordning samverkbar med ett antal i tandmall anordnade hylsor |
| US7621916B2 (en) * | 2004-11-18 | 2009-11-24 | Depuy Spine, Inc. | Cervical bone preparation tool and implant guide systems |
| ITBO20050545A1 (it) | 2005-09-06 | 2007-03-07 | Federico Franchini | Serie di strumenti chirurgici per implantologia dentale |
| DE202005014850U1 (de) * | 2005-09-20 | 2007-02-01 | Karl Leibinger Medizintechnik Gmbh & Co. Kg | System zur Fixierung von Knochensegmenten oder -fragmenten |
| US8540510B2 (en) | 2006-05-04 | 2013-09-24 | Nobel Biocare Services Ag | Device for securing a dental implant in bone tissue, a method for making a surgical template and a method of securing a dental implant in bone tissue |
| CN101578076B (zh) | 2007-01-10 | 2013-10-23 | 诺贝尔生物服务公司 | 用于牙设计和制备的方法和系统 |
| WO2008089885A1 (de) * | 2007-01-26 | 2008-07-31 | Friadent Gmbh | Anordnung mit einem instrument zur vorbereitung oder durchführung der insertion eines implantats |
| US7806693B2 (en) | 2007-04-23 | 2010-10-05 | Nobel Biocare Services Ag | Dental implant |
| US8343189B2 (en) * | 2007-09-25 | 2013-01-01 | Zyga Technology, Inc. | Method and apparatus for facet joint stabilization |
| US8740912B2 (en) | 2008-02-27 | 2014-06-03 | Ilion Medical Llc | Tools for performing less invasive orthopedic joint procedures |
| EP2254068B1 (en) | 2009-05-18 | 2020-08-19 | Nobel Biocare Services AG | Method and system providing improved data matching for virtual planning |
| ES2596828T3 (es) | 2009-09-07 | 2017-01-12 | Nobel Biocare Services Ag | Componentes para el roscado guiado de un hueso |
-
2009
- 2009-09-07 ES ES09011435T patent/ES2710179T3/es active Active
- 2009-09-07 EP EP09011435.6A patent/EP2292176B1/en active Active
-
2010
- 2010-09-06 KR KR1020127009019A patent/KR101745519B1/ko active Active
- 2010-09-06 WO PCT/EP2010/005449 patent/WO2011026644A2/en not_active Ceased
- 2010-09-06 BR BR112012005076A patent/BR112012005076B1/pt active IP Right Grant
- 2010-09-06 US US13/394,532 patent/US9259299B2/en active Active
- 2010-09-06 AU AU2010291502A patent/AU2010291502B2/en active Active
- 2010-09-06 JP JP2012527242A patent/JP5883385B2/ja active Active
- 2010-09-06 CN CN201080039471.3A patent/CN102481180B/zh active Active
-
2012
- 2012-02-23 ZA ZA2012/01362A patent/ZA201201362B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2744564A1 (de) * | 1977-10-04 | 1979-04-05 | Schmidt Rimpler Reimar Dr | Werkzeugkombination zur einsetzung von zahnimplataten |
| US5593410A (en) * | 1989-10-26 | 1997-01-14 | Vrespa; Giuseppe | Screw device for fixing prostheses to bones |
| US5643269A (en) * | 1990-08-24 | 1997-07-01 | Haerle; Anton | Externally threaded bodies for use as taps or screws |
| US20060079894A1 (en) * | 2003-10-21 | 2006-04-13 | Innovative Spinal Technologies | Connector transfer tool for internal structure stabilization systems |
| US20090136898A1 (en) * | 2007-11-26 | 2009-05-28 | Kim Soo Hong | Tap Drill for Dental Implant |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201201362B (en) | 2013-05-29 |
| BR112012005076A2 (pt) | 2017-06-06 |
| EP2292176A1 (en) | 2011-03-09 |
| AU2010291502A1 (en) | 2012-03-29 |
| EP2292176B1 (en) | 2019-01-09 |
| US20120191097A1 (en) | 2012-07-26 |
| US9259299B2 (en) | 2016-02-16 |
| CN102481180A (zh) | 2012-05-30 |
| WO2011026644A3 (en) | 2011-05-05 |
| WO2011026644A2 (en) | 2011-03-10 |
| JP2013503664A (ja) | 2013-02-04 |
| BR112012005076B1 (pt) | 2019-12-10 |
| ES2710179T3 (es) | 2019-04-23 |
| CN102481180B (zh) | 2016-09-28 |
| KR20120070581A (ko) | 2012-06-29 |
| KR101745519B1 (ko) | 2017-06-09 |
| JP5883385B2 (ja) | 2016-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |