AU2010268389B2 - Diagnostic method for predicting the risk of cancer recurrence based on histone macroH2A isoforms - Google Patents

Diagnostic method for predicting the risk of cancer recurrence based on histone macroH2A isoforms Download PDF

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Publication number
AU2010268389B2
AU2010268389B2 AU2010268389A AU2010268389A AU2010268389B2 AU 2010268389 B2 AU2010268389 B2 AU 2010268389B2 AU 2010268389 A AU2010268389 A AU 2010268389A AU 2010268389 A AU2010268389 A AU 2010268389A AU 2010268389 B2 AU2010268389 B2 AU 2010268389B2
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AU
Australia
Prior art keywords
cancer
expression
patient
macroh2a2
sample
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Ceased
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AU2010268389A
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English (en)
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AU2010268389A2 (en
AU2010268389A1 (en
Inventor
Andreas Ladurner
Thomas Muley
Judith Sporn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THORAXKLINIK-HEIDELBERG GGMBH
Europaisches Laboratorium fuer Molekularbiologie EMBL
Original Assignee
THORAXKLINIK HEIDELBERG GGMBH
Europaisches Laboratorium fuer Molekularbiologie EMBL
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Publication of AU2010268389A2 publication Critical patent/AU2010268389A2/en
Publication of AU2010268389A1 publication Critical patent/AU2010268389A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2010268389A 2009-07-02 2010-07-02 Diagnostic method for predicting the risk of cancer recurrence based on histone macroH2A isoforms Ceased AU2010268389B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09008679.4 2009-07-02
EP09008679A EP2270510A1 (en) 2009-07-02 2009-07-02 Diagnostic method for predicting the risk of cancer recurrence based on Histone macroH2A isoforms
PCT/EP2010/004008 WO2011000573A1 (en) 2009-07-02 2010-07-02 Diagnostic method for predicting the risk of cancer recurrence based on histone macroh2a isoforms

Publications (3)

Publication Number Publication Date
AU2010268389A2 AU2010268389A2 (en) 2012-01-12
AU2010268389A1 AU2010268389A1 (en) 2012-01-19
AU2010268389B2 true AU2010268389B2 (en) 2014-09-11

Family

ID=41100520

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010268389A Ceased AU2010268389B2 (en) 2009-07-02 2010-07-02 Diagnostic method for predicting the risk of cancer recurrence based on histone macroH2A isoforms

Country Status (11)

Country Link
US (1) US20120171225A1 (OSRAM)
EP (2) EP2270510A1 (OSRAM)
JP (1) JP5792165B2 (OSRAM)
CN (1) CN102472753B (OSRAM)
AU (1) AU2010268389B2 (OSRAM)
BR (1) BRPI1011925A2 (OSRAM)
CA (1) CA2766656A1 (OSRAM)
ES (1) ES2681687T3 (OSRAM)
SG (1) SG177398A1 (OSRAM)
WO (1) WO2011000573A1 (OSRAM)
ZA (1) ZA201109381B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201115098D0 (en) * 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants
GB201604806D0 (en) * 2016-03-22 2016-05-04 Singapore Volition Pte Ltd Method of identifying a cancer of unknown origin
EP3508855A1 (en) * 2018-01-05 2019-07-10 Allianz Pharmascience Ltd Method for the selection of patients and kit
EP3546944A1 (en) * 2018-03-30 2019-10-02 Universite d'Aix-Marseille (AMU) Diagnosis and treatment of a cancer based on the overexpression of the adamtsl5 gene
CN108957004B (zh) * 2018-07-09 2021-10-19 东南大学 检测H3K9me2和H3K36me3表达量的试剂在制备胃癌预后评估试剂盒中的应用
CN111896740B (zh) * 2019-05-06 2025-02-11 山东大学 诊断或预测生育缺陷的试剂盒
CN119736252B (zh) * 2025-01-15 2025-06-27 首都医科大学 组蛋白变体macroH2A调控巨噬细胞功能在改善肿瘤免疫微环境中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070148648A1 (en) * 2003-11-04 2007-06-28 Martin Dugas Method for distinguishing who classified aml subtypes
WO2009030770A2 (en) * 2007-09-07 2009-03-12 Universite Libre De Bruxelles Methods and tools for prognosis of cancer in er- patients

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GB2197915B (en) 1986-11-19 1990-11-14 Rolls Royce Plc Improvements in or relating to fluid bearings
EP1388734B1 (en) * 2002-08-01 2004-03-03 MTM Laboratories AG Method for solution based diagnosis
US20020052308A1 (en) * 1999-03-12 2002-05-02 Rosen Craig A. Nucleic acids, proteins and antibodies
US20030190640A1 (en) * 2001-05-31 2003-10-09 Mary Faris Genes expressed in prostate cancer
US20030124579A1 (en) * 2001-09-05 2003-07-03 Eos Biotechnology, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
WO2003064474A1 (fr) * 2002-01-31 2003-08-07 Japan Science And Technology Agency Production d'un hybridome produisant un anticorps monoclonal dirige contre des peptides de la proteine cenp-a humaine, et methode d'utilisation correspondante
CN100480382C (zh) * 2002-08-16 2009-04-22 抗癌公司 实时测量细胞反应
WO2004063355A2 (en) * 2003-01-10 2004-07-29 Protein Design Labs, Inc. Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer
EP2251039A3 (en) * 2003-05-30 2010-12-08 Nippon Shinyaku Co., Ltd. Oligo double-stranded rna inhibiting the expression of bcl-2 and pharmaceutical composition containing the same
DE102004037860A1 (de) * 2004-08-04 2006-03-16 Friedrich-Alexander-Universität Erlangen-Nürnberg Turmormarker zur Diagnose von Karzinomen und/oder davon abstammender Metastasen
WO2006119435A2 (en) * 2005-05-04 2006-11-09 Invitrogen Corporation Identification of cancer biomarkers and phosphorylated proteins
EP1907858A4 (en) * 2005-06-13 2009-04-08 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
WO2007054814A1 (en) * 2005-11-14 2007-05-18 Centre National De La Recherche Scientifique - Cnrs Inhibitors of parp activity and uses thereof
EP2145021A2 (en) * 2007-05-17 2010-01-20 Bristol-Myers Squibb Company Biomarkers and methods for determining sensitivity to insulin growth factor-1 receptor modulators
JP2008292424A (ja) * 2007-05-28 2008-12-04 Nippon Medical School 腫瘍の検出方法
WO2009146545A1 (en) * 2008-06-05 2009-12-10 University Health Network Compositions and methods for classifying lung cancer and prognosing lung cancer survival

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070148648A1 (en) * 2003-11-04 2007-06-28 Martin Dugas Method for distinguishing who classified aml subtypes
WO2009030770A2 (en) * 2007-09-07 2009-03-12 Universite Libre De Bruxelles Methods and tools for prognosis of cancer in er- patients

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Changolkar, L. N. et al., Molecular and Cellular Biology, 2007, Vol. 27, No. 7, pages 2758-2764 *
Pehrson, J. R. et al., Journal of Cellular Biochemistry, 1997, Vol. 65, pages 107-113 *

Also Published As

Publication number Publication date
ES2681687T3 (es) 2018-09-14
BRPI1011925A2 (pt) 2017-10-10
CN102472753A (zh) 2012-05-23
JP5792165B2 (ja) 2015-10-07
JP2012531612A (ja) 2012-12-10
ZA201109381B (en) 2012-08-29
CN102472753B (zh) 2015-02-11
US20120171225A1 (en) 2012-07-05
EP2449383A1 (en) 2012-05-09
EP2270510A1 (en) 2011-01-05
SG177398A1 (en) 2012-02-28
AU2010268389A2 (en) 2012-01-12
EP2449383B1 (en) 2018-05-16
CA2766656A1 (en) 2011-01-06
AU2010268389A1 (en) 2012-01-19
WO2011000573A1 (en) 2011-01-06

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