AU2010259986B2 - Co-administration of an agent linked to an internalization peptide with an anti-inflammatory - Google Patents
Co-administration of an agent linked to an internalization peptide with an anti-inflammatory Download PDFInfo
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- AU2010259986B2 AU2010259986B2 AU2010259986A AU2010259986A AU2010259986B2 AU 2010259986 B2 AU2010259986 B2 AU 2010259986B2 AU 2010259986 A AU2010259986 A AU 2010259986A AU 2010259986 A AU2010259986 A AU 2010259986A AU 2010259986 B2 AU2010259986 B2 AU 2010259986B2
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- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1072—Regulatory proteins, e.g. tat, rev, vpt
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US18594309P | 2009-06-10 | 2009-06-10 | |
| US61/185,943 | 2009-06-10 | ||
| PCT/US2010/038226 WO2010144742A2 (en) | 2009-06-10 | 2010-06-10 | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
Publications (2)
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| AU2010259986A1 AU2010259986A1 (en) | 2012-01-12 |
| AU2010259986B2 true AU2010259986B2 (en) | 2015-04-02 |
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|---|---|---|---|
| AU2010259986A Ceased AU2010259986B2 (en) | 2009-06-10 | 2010-06-10 | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
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| EP (2) | EP2440231B1 (enExample) |
| JP (5) | JP5886192B2 (enExample) |
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| CY (1) | CY1122584T1 (enExample) |
| DK (1) | DK2440231T3 (enExample) |
| ES (1) | ES2765281T3 (enExample) |
| HR (1) | HRP20192230T1 (enExample) |
| HU (1) | HUE046640T2 (enExample) |
| LT (1) | LT2440231T (enExample) |
| PL (1) | PL2440231T3 (enExample) |
| PT (1) | PT2440231T (enExample) |
| SI (1) | SI2440231T1 (enExample) |
| SM (1) | SMT202000056T1 (enExample) |
| WO (1) | WO2010144742A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8080518B2 (en) | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| PL2320927T3 (pl) * | 2008-07-09 | 2016-02-29 | Univ Copenhagen | Modyfikowane peptydy jako potencjalne inhibitory w reakcjach receptorów PSD 95 i NMD |
| AU2010259986B2 (en) | 2009-06-10 | 2015-04-02 | Nono Inc. | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| HRP20171564T1 (hr) | 2009-09-22 | 2017-11-17 | Medicago Inc. | Postupak za pripremu biljnih čestica sličnih virusu (vlp) |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| KR102022116B1 (ko) | 2011-06-24 | 2019-09-18 | 노노 인코포레이티드 | 허혈에 대한 psd-95 억제제와의 조합 요법 |
| US10251935B2 (en) | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| HUE043820T2 (hu) * | 2012-11-28 | 2019-09-30 | Nono Inc | Liofilizált TAT-NR2B9c készítmény |
| WO2016172219A1 (en) * | 2015-04-24 | 2016-10-27 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods and compositions for inhibition of toll-like receptors (tlrs)-mediated inflammation |
| US10808253B2 (en) | 2015-12-28 | 2020-10-20 | Idemitsu Kosan Co., Ltd. | Peptide tag and tagged protein including same |
| EA039314B1 (ru) * | 2017-07-05 | 2022-01-12 | Биоселз (Бейдзин) Биотек Ко., Лтд. | Фармацевтически приемлемые соли полипептидов и их применение |
| CA3079081A1 (en) | 2017-10-19 | 2019-04-25 | Michael D. Bartberger | Benzimidazole derivatives and their uses |
| CN115279797A (zh) * | 2020-01-09 | 2022-11-01 | 诺诺公司 | 用于治疗中风和相关疾病的抗纤溶酶肽 |
| EP4274596A4 (en) | 2021-01-08 | 2024-12-25 | NoNO Inc. | Plasmin-resistant peptides for improved therapeutic index |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20030050243A1 (en) * | 1999-06-02 | 2003-03-13 | Michael Tymianski | Method of reducing injury to mammalian cells |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5804604A (en) | 1989-12-21 | 1998-09-08 | Biogen, Inc. | Tat-derived transport polypeptides and fusion proteins |
| US6316003B1 (en) | 1989-12-21 | 2001-11-13 | Whitehead Institute For Biomedical Research | Tat-derived transport polypeptides |
| US5331573A (en) | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
| EP1159418A2 (en) | 1998-12-11 | 2001-12-05 | Biomira Inc. | Muc-1 antagonists and methods of treating immune disorders |
| US20040226056A1 (en) | 1998-12-22 | 2004-11-11 | Myriad Genetics, Incorporated | Compositions and methods for treating neurological disorders and diseases |
| US20060148711A1 (en) | 1999-05-14 | 2006-07-06 | Arbor Vita Corporation | Molecular interactions in neurons |
| US7510824B2 (en) * | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| DE60026313D1 (de) | 1999-07-23 | 2006-04-27 | Uutech Ltd | Sensibilisierung von roten blutkörperchen gegenüber ultraschall durch einwirkung eines elektrischen feldes |
| MXPA02001857A (es) | 1999-08-24 | 2003-07-14 | Cellgate Inc | Composiciones y metodos para incrementar la entrega de drogas a traves y dentro de tejidos epiteliales. |
| US6204245B1 (en) | 1999-09-17 | 2001-03-20 | The Regents Of The University Of California | Treatment of narcolepsy with immunosuppressants |
| US6864355B1 (en) | 2000-05-02 | 2005-03-08 | Yale University | Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain |
| US20020032154A1 (en) | 2000-06-07 | 2002-03-14 | Peyman John A. | Interferon-suppressing placental lactogen peptides |
| AU2002356511A1 (en) | 2001-07-30 | 2003-04-01 | Immunex Corporation | T. reesei phytase enyzmes, polynucleides encoding the enzymes, vectors and host cells thereof, and methods of using |
| WO2004045535A2 (en) * | 2002-11-14 | 2004-06-03 | Arbor Vita Corporation | Molecular interactions in neurons |
| US20060276455A1 (en) | 2003-02-13 | 2006-12-07 | Lindsberg Perttu J | Use of a mast cell activation or degranulation blocking agent in the manufacture of a medicament for the treatment of cerebral ischemia |
| WO2005037317A2 (en) * | 2003-10-17 | 2005-04-28 | Cornell Research Foundation, Inc. | Mast cell-derived renin |
| US20050256065A1 (en) * | 2004-01-26 | 2005-11-17 | Permasight | Method for stabilizing changes in corneal curvature in an eye by administering compositions containing stabilizing ophthalmic agents |
| US7151084B2 (en) | 2004-12-27 | 2006-12-19 | Miller Landon C G | Compound and method of treating neurogenic conditions using non-steroidal anti-inflammatory drug complexes |
| KR101384572B1 (ko) | 2005-12-30 | 2014-04-24 | 아버 비타 코포레이션 | Ｐｄｚ 상호작용의 소형 분자 억제제 |
| ES2804424T3 (es) * | 2006-07-11 | 2021-02-08 | Nono Inc | Péptido y composición del mismo para usar en el tratamiento del accidente cerebrovascular con fiebre |
| EP1884521A1 (en) * | 2006-07-31 | 2008-02-06 | Xigen S.A. | Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins |
| EP2120987B1 (en) * | 2007-03-02 | 2014-01-15 | NoNO Inc. | Treating stroke and other diseases without inhibiting n-type calcium channels |
| WO2009006611A1 (en) | 2007-07-03 | 2009-01-08 | Arbor Vita Corporation | Small molecule inhibitors of pdz interactions |
| EP2178549B1 (en) | 2007-07-26 | 2016-09-14 | Revance Therapeutics, Inc. | Antimicrobial peptide and compositions thereof |
| ES2328776B1 (es) | 2007-11-19 | 2010-07-06 | Proyecto De Biomedicina Cima S.L. | Peptidos con capacidad para unirse a escurfina y aplicaciones. |
| US8080518B2 (en) | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| PL2320927T3 (pl) | 2008-07-09 | 2016-02-29 | Univ Copenhagen | Modyfikowane peptydy jako potencjalne inhibitory w reakcjach receptorów PSD 95 i NMD |
| AU2010259986B2 (en) | 2009-06-10 | 2015-04-02 | Nono Inc. | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
-
2010
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- 2010-06-10 EP EP10786870.5A patent/EP2440231B1/en active Active
- 2010-06-10 SI SI201031965T patent/SI2440231T1/sl unknown
- 2010-06-10 EP EP19210675.5A patent/EP3682895A1/en not_active Withdrawn
- 2010-06-10 SM SM20200056T patent/SMT202000056T1/it unknown
- 2010-06-10 PT PT107868705T patent/PT2440231T/pt unknown
- 2010-06-10 CA CA3018494A patent/CA3018494C/en active Active
- 2010-06-10 LT LTEP10786870.5T patent/LT2440231T/lt unknown
- 2010-06-10 WO PCT/US2010/038226 patent/WO2010144742A2/en not_active Ceased
- 2010-06-10 DK DK10786870.5T patent/DK2440231T3/da active
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- 2010-06-10 CA CA2765171A patent/CA2765171C/en active Active
- 2010-06-10 HR HRP20192230TT patent/HRP20192230T1/hr unknown
- 2010-06-10 US US13/377,519 patent/US8933013B2/en active Active
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2014
- 2014-12-29 US US14/585,028 patent/US9433685B2/en not_active Expired - Fee Related
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2015
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2016
- 2016-08-24 US US15/245,693 patent/US10046060B2/en active Active
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2017
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2018
- 2018-07-12 US US16/034,235 patent/US20190038760A1/en not_active Abandoned
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2019
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2022
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030050243A1 (en) * | 1999-06-02 | 2003-03-13 | Michael Tymianski | Method of reducing injury to mammalian cells |
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