AU2010204766B2 - Methods for improving hepatic and immune function in an animal - Google Patents

Methods for improving hepatic and immune function in an animal Download PDF

Info

Publication number
AU2010204766B2
AU2010204766B2 AU2010204766A AU2010204766A AU2010204766B2 AU 2010204766 B2 AU2010204766 B2 AU 2010204766B2 AU 2010204766 A AU2010204766 A AU 2010204766A AU 2010204766 A AU2010204766 A AU 2010204766A AU 2010204766 B2 AU2010204766 B2 AU 2010204766B2
Authority
AU
Australia
Prior art keywords
lipoic acid
ppm
composition
salt
immune function
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2010204766A
Other languages
English (en)
Other versions
AU2010204766A1 (en
Inventor
Inke Paetau-Robinson
Steven C. Zicker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hills Pet Nutrition Inc
Original Assignee
Hills Pet Nutrition Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hills Pet Nutrition Inc filed Critical Hills Pet Nutrition Inc
Publication of AU2010204766A1 publication Critical patent/AU2010204766A1/en
Application granted granted Critical
Publication of AU2010204766B2 publication Critical patent/AU2010204766B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Feed For Specific Animals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
AU2010204766A 2009-01-14 2010-01-14 Methods for improving hepatic and immune function in an animal Active AU2010204766B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/353,351 US20090176864A1 (en) 2004-11-24 2009-01-14 Methods For Improving Hepatic and Immune Function In An Animal
US12/353,351 2009-01-14
PCT/US2010/020993 WO2010083277A2 (en) 2009-01-14 2010-01-14 Methods for improving hepatic and immune function in an animal

Publications (2)

Publication Number Publication Date
AU2010204766A1 AU2010204766A1 (en) 2011-07-21
AU2010204766B2 true AU2010204766B2 (en) 2013-01-31

Family

ID=42124569

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010204766A Active AU2010204766B2 (en) 2009-01-14 2010-01-14 Methods for improving hepatic and immune function in an animal

Country Status (12)

Country Link
US (2) US20090176864A1 (ja)
EP (1) EP2387325B1 (ja)
JP (1) JP5791520B2 (ja)
CN (2) CN106036037A (ja)
AU (1) AU2010204766B2 (ja)
BR (1) BRPI1007294A2 (ja)
CA (2) CA2843448A1 (ja)
DK (1) DK2387325T3 (ja)
ES (1) ES2603986T3 (ja)
RU (1) RU2485797C2 (ja)
WO (1) WO2010083277A2 (ja)
ZA (1) ZA201104624B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8669282B2 (en) * 2000-10-31 2014-03-11 Hill's Pet Nutrition, Inc. Companion animal compositions including lipoic acid and methods of use thereof
US20020076470A1 (en) 2000-10-31 2002-06-20 Colgate-Palmolive Company Composition and method
US20090176864A1 (en) * 2004-11-24 2009-07-09 Hill's Pet Nutrition, Inc. Methods For Improving Hepatic and Immune Function In An Animal
CA2588709C (en) * 2004-11-24 2015-07-14 Hill's Pet Nutrition, Inc. Use of lipoic acid to improve hepatic clearance of xenobiotic substances
CN104304671A (zh) 2004-12-29 2015-01-28 希尔氏宠物营养品公司 抑制动物学习和/或记忆减退的方法
CA2592844C (en) * 2004-12-30 2012-10-09 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
US8252742B2 (en) 2004-12-30 2012-08-28 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
US8722112B2 (en) * 2005-07-14 2014-05-13 Hill's Pet Nutrition, Inc. Method for prolonging the life of animals
CN105639121A (zh) * 2009-07-14 2016-06-08 希尔氏宠物营养品公司 包括持续释放的硫辛酸的宠物食品组合物及其制造和使用方法
CN102657297A (zh) * 2012-05-30 2012-09-12 扬州大学 一种调控高产奶牛围产期氧化应激的方法
US20210369661A1 (en) * 2020-05-27 2021-12-02 Immunoflex Therapeutics Inc. Methods and compositions for treating and recovering from viral infections

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5621117A (en) * 1994-07-30 1997-04-15 Asta Medica Aktiengesellschaft Method for the racemization of enantiomers of α-lipoic acid
US5994393A (en) * 1998-03-11 1999-11-30 Asta Medica Aktiengesellschaft Alpha-lipoic acid with novel modification
US6197340B1 (en) * 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
US20020076469A1 (en) * 2000-10-31 2002-06-20 Colgate-Palmolive Company Composition and method
US20030224061A1 (en) * 2002-06-04 2003-12-04 Pacioretty Linda M. Oral composition with insulin-like activities and methods of use
US20040138311A1 (en) * 2001-05-28 2004-07-15 Michael Taeger Medicament containing an effector of the glutathione metabolism together with $g(a)-lipoic acid for treating diabetes mellitus
US20050123628A1 (en) * 2003-12-03 2005-06-09 George Zabrecky Compositions and methods useful for treating and preventing chronic liver disease, chronic HCV infection and non-alcoholic steatohepatitis
US6914071B2 (en) * 2000-10-31 2005-07-05 Colgate-Palmolive Company Antioxidant containing composition and method
WO2006058248A2 (en) * 2004-11-24 2006-06-01 Hill's Pet Nutrition, Inc. Methods for increasing the immune response in an animal
KR20060072603A (ko) * 2004-12-23 2006-06-28 한서제약 주식회사 α-리포산 함유 간질환 예방 또는 치료용 조성물
KR20070025426A (ko) * 2005-09-02 2007-03-08 부광약품 주식회사 D-(+)-α-리포산 트로메타민염을 포함하는 간섬유화 억제 및 치료용 조성물

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2980716A (en) * 1954-06-11 1961-04-18 Research Corp Method for preparing 6, 8-dihalooctanoic esters
US2890716A (en) * 1956-03-16 1959-06-16 Buensod Stacey Inc Control device
US3202514A (en) * 1963-07-15 1965-08-24 Gen Foods Corp Animal food and method of making the same
US6090414A (en) * 1970-05-20 2000-07-18 Life Science Labs, Inc. Method and composition to reduce cancer incidence
US3946123A (en) * 1975-03-10 1976-03-23 Star-Kist Foods, Inc. Canned pet food
US4053647A (en) * 1975-12-12 1977-10-11 Samuel Prussin Pet food product and process of producing such
US4247562A (en) * 1978-12-21 1981-01-27 The Quaker Oats Company Moist pet food with blood chunks and a fluid gravy system
DE3378909D1 (en) * 1982-10-20 1989-02-16 Takeda Chemical Industries Ltd Physiologically active substance p-23924, its production and use
US5004624A (en) * 1983-03-14 1991-04-02 Star-Kist Foods, Inc. Semi-moist pet food having free gravy and process for preparation thereof
EP0270690B1 (en) * 1986-06-21 1991-05-15 Dainippon Ink And Chemicals, Inc. Drug for treatment and prophylaxis of kidney and liver diseases
US5030458A (en) * 1989-11-27 1991-07-09 Shug Austin L Method for preventing diet-induced carnitine deficiency in domesticated dogs and cats
US4997672A (en) * 1987-03-10 1991-03-05 Virginia Commonwealth University Salt taste enhancer
ES2043897T3 (es) * 1988-01-28 1994-01-01 Koeltringer Peter Preparado de combinacion, en especial para el tratamiento de enfermedades de las celulas nerviosas.
US6977167B2 (en) * 1988-09-07 2005-12-20 Martek Biosciences Corporation Mixtures of omega-3 and omega-6 highly unsaturated fatty acids from euryhaline microorganisms
US4997671A (en) * 1988-09-09 1991-03-05 Nabisco Brands, Inc. Chewy dog snacks
US5114704A (en) * 1989-05-30 1992-05-19 Nabisco Brands, Inc. Raw hide having a coating containing an inorganic pyrophosphate
IE904034A1 (en) * 1989-11-09 1991-05-22 Asta Medica Ag A medicament containing r-ó-lipoic acid or s-ó-lipoic acid¹as active substance
US6746678B1 (en) * 1991-02-22 2004-06-08 Howard K. Shapiro Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments
US5419283A (en) * 1992-04-08 1995-05-30 Ciuffo Gatto S.R.L. Animal chew toy of starch material and degradable ethylene copolymer
US5569670A (en) * 1992-06-05 1996-10-29 Asta Medica Aktiengesellschaft Combination medications containing alpha-lipoic acid and related
US5624896A (en) * 1992-06-09 1997-04-29 Neorx Corporation Clearing agents useful in pretargeting methods
US5292538A (en) * 1992-07-22 1994-03-08 Metagenics, Inc. Improved sustained energy and anabolic composition and method of making
DE4235912C2 (de) * 1992-10-23 2002-12-05 Viatris Gmbh Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung
JP3347381B2 (ja) * 1993-01-27 2002-11-20 協和醗酵工業株式会社 ペットフード
US5532010A (en) * 1993-05-28 1996-07-02 Nabisco, Inc. Coated canine biscuits and preparation process
US5339771A (en) * 1993-09-15 1994-08-23 Axelrod Herbert R Animal chew toy containing animal meal
WO1995013824A1 (en) * 1993-11-15 1995-05-26 Celtrix Pharmaceuticals, Inc. Method of treating renal disease by administering igf-i and igfbp-3
US6458767B1 (en) * 1994-05-04 2002-10-01 The Uab Research Foundation Use of peptides inhibitory for thrombospondin dependent TGF-β activation in the treatment of kidney disease
US5599835A (en) * 1994-11-23 1997-02-04 Fischer; Frederick B. Use of DL-lipoic acid as a medical food in the treatment of diabetes mellitus
US5621177A (en) * 1995-03-02 1997-04-15 Yokogawa Electric Corporation Electromagnetic flowmeter
US5730988A (en) * 1995-04-20 1998-03-24 Lynntech, Inc. Nutritional supplements for improving glucose metabolism
US6184227B1 (en) * 1995-07-21 2001-02-06 Savvipharm Inc. Salts of aminoimidazole carboxamide useful in the prevention and treatment of liver diseases
FR2738741B1 (fr) * 1995-09-19 1997-12-05 Oreal Composition pour la teinture des fibres keratiniques, contenant un antagoniste de substance p
CA2208392C (en) * 1996-06-21 2002-09-03 University Of Guelph Method for enriching docosahexaenoic acid in expressed milk of dairy cattle
US5965596A (en) * 1997-08-12 1999-10-12 Harris; Roger Methods and compositions for increasing the anaerobic working capacity in tissue
US6190591B1 (en) * 1996-10-28 2001-02-20 General Mills, Inc. Embedding and encapsulation of controlled release particles
US6232346B1 (en) * 1997-03-27 2001-05-15 Michael J. Sole Composition for improvement of cellular nutrition and mitochondrial energetics
US6080788A (en) * 1997-03-27 2000-06-27 Sole; Michael J. Composition for improvement of cellular nutrition and mitochondrial energetics
US6133323A (en) * 1997-04-09 2000-10-17 The Iams Company Process for enhancing immune response in animals using β-carotene as a dietary supplement
US5883083A (en) * 1997-06-09 1999-03-16 Harlmen, Inc. Dietary supplement for alleviating behavioral problems in canines and reducing seizures in canines and felines
US5916912A (en) * 1997-06-16 1999-06-29 The Regents Of The University Of California Dietary composition for enhancing metabolism and alleviating oxidative stress
US6039952A (en) * 1997-10-22 2000-03-21 The Iams Company Composition and method for improving clinical signs in animals with renal disease
US6365623B1 (en) * 1997-11-17 2002-04-02 Nicholas V. Perricone Treatment of acne using lipoic acid
US6117477A (en) * 1998-03-18 2000-09-12 Kal Kan Foods, Inc. Multicomponent food product and methods of making and using the same
DE19834608A1 (de) * 1998-07-31 2000-02-03 Basf Ag Kristallmodifikation der Liponsäure
US6136339A (en) * 1998-08-21 2000-10-24 Gardiner; Paul T. Food supplements and methods comprising lipoic acid and creatine
IT1302307B1 (it) * 1998-09-01 2000-09-05 Sigma Tau Healthscience Spa Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil
AUPP784398A0 (en) * 1998-12-21 1999-01-21 Monash University Kidney disease detection and treatment
BR9916407A (pt) * 1998-12-21 2001-09-25 Univ Monash Detecção e tratamento de doenças dos rins
US20040029175A1 (en) * 1998-12-21 2004-02-12 Comper Wayne D. Method for kidney disease detection
US6284786B1 (en) * 1999-02-16 2001-09-04 The Center For The Improvement Of Human Functioning, Int'l., Inc. Treatment of cancer using lipoic acid in combination with ascorbic acid
DK1033364T3 (da) * 1999-03-01 2005-06-06 Pfizer Prod Inc Cyanholdige oxamidsyrer og -derivater som thyroideareceptorligander
IT1306130B1 (it) * 1999-04-16 2001-05-30 Sigma Tau Healthscience Spa Composizione comprendente una carnitina e glutatione, atta adaumentare l'assorbimento del glutatione sinergizzandone gli effetti.
ATE301937T1 (de) * 1999-05-27 2005-09-15 Iams Company Verfahren zur herstellung eines produkts zur erhöhung der immunantwort bei haustieren mit verwendung einer kombination von antioxidantien
US6365211B1 (en) * 1999-06-18 2002-04-02 The Procter & Gamble Co. Cooking aid with reduced foaming
US6426362B1 (en) * 1999-10-08 2002-07-30 Galileo Laboratories, Inc. Formulations of tocopherols and methods of making and using them
IL149421A0 (en) * 1999-11-02 2002-11-10 Depomed Inc Pharmaceutical compositions containing fed mode inducing agents
WO2001032168A1 (en) * 1999-11-03 2001-05-10 Juvenon, Inc. Method of treating benign forgetfulness
US6379727B1 (en) * 1999-12-29 2002-04-30 John F. Addy Flavoring system for pet foods
US20030060503A1 (en) * 2000-01-25 2003-03-27 Juvenon, Inc. Nutritional supplements for mature pets
KR20020090214A (ko) * 2000-02-01 2002-11-30 머슬테크 리서치 앤드 디벨롭먼트, 인크. 근육을 키우거나 강도를 늘리기 위한 α리포산계의보조식품
JP4487376B2 (ja) * 2000-03-31 2010-06-23 味の素株式会社 腎疾患治療剤
US7067145B2 (en) * 2000-09-07 2006-06-27 University Of Maryland Biotechnology Institute Use of arachidonic acid for enhanced culturing of fish larvae and broodstock
US6784159B2 (en) * 2000-09-29 2004-08-31 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture Triterpene saponins from soybeans for treating kidney disease
US6277842B1 (en) * 2000-10-17 2001-08-21 James Alexander Carthron Dietary supplemental method for fat and weight reduction
US20020115710A1 (en) * 2000-10-31 2002-08-22 Zicker Steven Curtis Composition and method
US8592479B2 (en) * 2000-10-31 2013-11-26 Hill's Pet Nutrition, Inc. Antioxidant-containing food composition for use in enhancing antiviral immunity in companion animals
US20090156658A1 (en) * 2000-10-31 2009-06-18 Hill's Pet Nutrition, Inc. Antioxidant-Containing Food Composition For Use In Inhibiting Histamine Pathways In Companion Animals
JP2004514686A (ja) * 2000-10-31 2004-05-20 コルゲート・パーモリブ・カンパニー 組成物と方法
US20020052402A1 (en) * 2000-10-31 2002-05-02 Colgate-Palmolive Company Composition and method
US8669282B2 (en) * 2000-10-31 2014-03-11 Hill's Pet Nutrition, Inc. Companion animal compositions including lipoic acid and methods of use thereof
DE60039726D1 (de) * 2000-12-29 2008-09-11 Martin Francis Gannon Tiernahrungsmittelzusammensetzung
US20030190314A1 (en) * 2001-01-30 2003-10-09 The Lauridsen Group Methods and compositions of treatment for modulating the immune system of animals
CA2439078C (en) * 2001-03-09 2009-08-25 Societe Des Produits Nestle S.A. Composition improving age-related physiological deficits and increasing longevity
CA2446027C (en) * 2001-05-14 2009-04-28 Martek Biosciences Corporation A method of improving the flavor, tenderness and overall consumer acceptability of poultry meat
US6596762B2 (en) * 2001-05-17 2003-07-22 The Regents Of The University Of Colorado Antioxidant compositions and use for treatment of hepatic steatosis and steatohepatitis
US6596768B2 (en) * 2001-05-22 2003-07-22 Church & Dwight Co., Inc. Unsaturated lipid-enriched feedstock for ruminants
US6902739B2 (en) * 2001-07-23 2005-06-07 Nutracea Methods for treating joint inflammation, pain, and loss of mobility
GB0119052D0 (en) * 2001-08-03 2001-09-26 Mars Uk Ltd Foodstuff
DE10151764A1 (de) * 2001-10-19 2003-05-08 Basf Ag Kombination von Liponsäure und Glutamin in Lebens- und Arzneimitteln
US20030190343A1 (en) * 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
US20030194478A1 (en) * 2002-04-12 2003-10-16 Davenport Gary Mitchell Dietary methods for canine performance enhancement
US8841344B2 (en) * 2002-10-03 2014-09-23 Hill's Pet Nutrition, Inc. Method of using omega-3 fatty acids
CA2525560A1 (en) * 2003-05-13 2004-11-25 The Regents Of The University Of Colorado Diagnostic and therapeutic treatments related to mitochondrial disorders
US7202270B2 (en) * 2003-06-20 2007-04-10 Sami Labs Limited Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts: process for their manufacture and uses
WO2006012267A1 (en) * 2004-06-29 2006-02-02 Elixirin Corporation Dietary compositions for enhancing metabolism and reducing reactive oxygen species
US20060002985A1 (en) * 2004-07-02 2006-01-05 Zicker Steven C Compositions and methods for decreasing age-related deterioration in mental activities in companion animals
US20090176864A1 (en) * 2004-11-24 2009-07-09 Hill's Pet Nutrition, Inc. Methods For Improving Hepatic and Immune Function In An Animal
CA2588709C (en) * 2004-11-24 2015-07-14 Hill's Pet Nutrition, Inc. Use of lipoic acid to improve hepatic clearance of xenobiotic substances
US8168161B2 (en) * 2004-12-22 2012-05-01 Hill's Pet Nutrition, Inc. Method to promote oral health in companion animals
CN104304671A (zh) * 2004-12-29 2015-01-28 希尔氏宠物营养品公司 抑制动物学习和/或记忆减退的方法
US8722112B2 (en) * 2005-07-14 2014-05-13 Hill's Pet Nutrition, Inc. Method for prolonging the life of animals
BRPI0615211A2 (pt) * 2005-08-17 2013-01-15 Hills Pet Nutrition Inc composiÇço, mÉtodo para evitar ou tratar doenÇa renal ou para a melhora da funÇço renal, kit, e, meio para comunicar informaÇço sobre ou instruÇÕes para a mistura e administraÇço de um ou mais das composiÇÕes, componentes de composiÇço, composiÇÕes alimentÍcias, ingredientes alimentÍcios e medicamentos renais e para uso dos dispositivos de diagnàstico renal
KR100811110B1 (ko) * 2007-02-21 2008-03-06 주식회사 디피아이 솔루션스 수분산성 α-리포산 캡슐 조성물을 함유하는 어류의 면역력증강용 사료첨가제 및 그 사용방법.

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5621117A (en) * 1994-07-30 1997-04-15 Asta Medica Aktiengesellschaft Method for the racemization of enantiomers of α-lipoic acid
US5994393A (en) * 1998-03-11 1999-11-30 Asta Medica Aktiengesellschaft Alpha-lipoic acid with novel modification
US6197340B1 (en) * 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
US20020076469A1 (en) * 2000-10-31 2002-06-20 Colgate-Palmolive Company Composition and method
US6914071B2 (en) * 2000-10-31 2005-07-05 Colgate-Palmolive Company Antioxidant containing composition and method
US20040138311A1 (en) * 2001-05-28 2004-07-15 Michael Taeger Medicament containing an effector of the glutathione metabolism together with $g(a)-lipoic acid for treating diabetes mellitus
US20030224061A1 (en) * 2002-06-04 2003-12-04 Pacioretty Linda M. Oral composition with insulin-like activities and methods of use
US20050123628A1 (en) * 2003-12-03 2005-06-09 George Zabrecky Compositions and methods useful for treating and preventing chronic liver disease, chronic HCV infection and non-alcoholic steatohepatitis
WO2006058248A2 (en) * 2004-11-24 2006-06-01 Hill's Pet Nutrition, Inc. Methods for increasing the immune response in an animal
KR20060072603A (ko) * 2004-12-23 2006-06-28 한서제약 주식회사 α-리포산 함유 간질환 예방 또는 치료용 조성물
KR20070025426A (ko) * 2005-09-02 2007-03-08 부광약품 주식회사 D-(+)-α-리포산 트로메타민염을 포함하는 간섬유화 억제 및 치료용 조성물

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CUI, J. et al., Cellular Immunology, 2009, 260, 44-50 *
LEY, B. M., http://web.archive.org/web/20000614235007/http://www.tldp.com/issue/160/160alpha.htm, 14 June 2000 *
OHMORI, H. et al., Japan J. Pharmacol., 1986, 42, 275-280 *

Also Published As

Publication number Publication date
CN102281769A (zh) 2011-12-14
EP2387325B1 (en) 2016-08-17
US20110135785A1 (en) 2011-06-09
CN106036037A (zh) 2016-10-26
ES2603986T3 (es) 2017-03-02
JP2012515211A (ja) 2012-07-05
CA2749280A1 (en) 2010-07-22
WO2010083277A2 (en) 2010-07-22
RU2485797C2 (ru) 2013-06-27
ZA201104624B (en) 2015-02-25
EP2387325A2 (en) 2011-11-23
RU2011134077A (ru) 2013-02-20
JP5791520B2 (ja) 2015-10-07
DK2387325T3 (en) 2016-12-05
WO2010083277A3 (en) 2011-01-06
US20090176864A1 (en) 2009-07-09
AU2010204766A1 (en) 2011-07-21
BRPI1007294A2 (pt) 2015-08-25
CA2749280C (en) 2014-05-06
CA2843448A1 (en) 2010-07-22

Similar Documents

Publication Publication Date Title
AU2010204766B2 (en) Methods for improving hepatic and immune function in an animal
Baetz et al. Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis.
Sadahira et al. Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness.
Alvarez et al. ER to Golgi transport: requirement for p115 at a pre-Golgi VTC stage
Nau The methylation of tRNA
Kirchhoff et al. Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during sperm maturation
Reid et al. Red blood cell blood group antigens: structure and function
Niehaus et al. Cell-surface glycoprotein of oligodendrocyte progenitors involved in migration
Hwang et al. Age-associated decrease in proteasome content and activities in human dermal fibroblasts: restoration of normal level of proteasome subunits reduces aging markers in fibroblasts from elderly persons
Wuytack et al. The Ca 2+-transport ATPases from the plasma membrane
Weerth et al. Signaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells
Gibbs et al. Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding
Markova et al. Sodium/calcium exchanger is upregulated by sulfide signaling, forms complex with the β1 and β3 but not β2 adrenergic receptors, and induces apoptosis
Bast et al. Idiotypic peripheral blood lymphocytes in monoclonal gammopathy
Lawrence et al. Inhibition of protein synthesis separates autophagic sequestration from the delivery of lysosomal enzymes
Tiengwe et al. Surface proteins, ERAD and antigenic variation in Trypanosoma brucei
Shigeri et al. Y2 receptors for neuropeptide Y are coupled to three intracellular signal transduction pathways in a human neuroblastoma cell line.
Choi et al. Vitamin E prevents oxidation of antiapoptotic proteins in neuronal cells
Van Lier et al. T cell receptor/CD3 and CD28 use distinct intracellular signaling pathways
Foster et al. Markers of the metastatic phenotype in prostate cancer
Crouch et al. Insulin induces epidermal growth factor (EGF) receptor clustering and potentiates EGF‐stimulated DNA synthesis in Swiss 3T3 cells: a mechanism for costimulation in mitogenic synergy
Piontek et al. Differential and regulated binding of cAMP-dependent protein kinase and protein kinase C isoenzymes to gravin in human model neurons: evidence that gravin provides a dynamic platform for the localization of kinases during neuronal development
AU680198B2 (en) Antigenic regions of tumour-liberated particles (TLP) complexes and antibodies against them
Mahabaleshwar et al. Slit‐Robo signalling establishes a Sphingosine‐1‐phosphate gradient to polarise fin mesenchyme
Pain Protein synthesis in a postmitochondrial supernatant system from rat liver. An effect of diabetes at the level of peptide chain initiation

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)