AU2010204178B2 - Complex and production process - Google Patents

Complex and production process Download PDF

Info

Publication number
AU2010204178B2
AU2010204178B2 AU2010204178A AU2010204178A AU2010204178B2 AU 2010204178 B2 AU2010204178 B2 AU 2010204178B2 AU 2010204178 A AU2010204178 A AU 2010204178A AU 2010204178 A AU2010204178 A AU 2010204178A AU 2010204178 B2 AU2010204178 B2 AU 2010204178B2
Authority
AU
Australia
Prior art keywords
lactalbumin
recombinant protein
biologically active
complex
active complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2010204178A
Other languages
English (en)
Other versions
AU2010204178A1 (en
Inventor
Kenneth Hun Mok
Ann-Kristin Mossberg
Jenny Petterson-Kastberg
Catharina Svanborg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamlet Pharma AB
Original Assignee
Hamlet Pharma AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0900260A external-priority patent/GB0900260D0/en
Priority claimed from GB0906199A external-priority patent/GB0906199D0/en
Application filed by Hamlet Pharma AB filed Critical Hamlet Pharma AB
Publication of AU2010204178A1 publication Critical patent/AU2010204178A1/en
Application granted granted Critical
Publication of AU2010204178B2 publication Critical patent/AU2010204178B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU2010204178A 2009-01-09 2010-01-08 Complex and production process Active AU2010204178B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0900260A GB0900260D0 (en) 2009-01-09 2009-01-09 Complex and production process
GB0900260.1 2009-01-09
GB0906199A GB0906199D0 (en) 2009-04-09 2009-04-09 Complex and production process
GB0906199.5 2009-04-09
PCT/GB2010/050024 WO2010079362A1 (en) 2009-01-09 2010-01-08 Complex and production process

Publications (2)

Publication Number Publication Date
AU2010204178A1 AU2010204178A1 (en) 2011-09-01
AU2010204178B2 true AU2010204178B2 (en) 2015-10-29

Family

ID=42026257

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010204178A Active AU2010204178B2 (en) 2009-01-09 2010-01-08 Complex and production process

Country Status (8)

Country Link
US (1) US8796218B2 (https=)
EP (1) EP2385954B1 (https=)
JP (1) JP5679992B2 (https=)
CN (1) CN102348721A (https=)
AU (1) AU2010204178B2 (https=)
CA (1) CA2752490C (https=)
DK (1) DK2385954T3 (https=)
WO (1) WO2010079362A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8796218B2 (en) 2009-01-09 2014-08-05 Hamlet Pharma Ab Complex and production process
ES2613986T3 (es) 2010-11-24 2017-05-29 Hamlet Pharma Ab Complejo biológicamente activo y su preparación
HUE038910T2 (hu) 2012-08-09 2018-12-28 Hamlet Pharma Ab Profilaktikus és gyógytáp terápia
CN106636157A (zh) * 2016-09-01 2017-05-10 锦州医科大学 一种突变α‑乳清蛋白表达载体、制备方法及其应用
GB201621752D0 (en) * 2016-12-20 2017-02-01 Hamlet Pharma Ab Therapeutically active complexes
GB201707715D0 (en) * 2017-05-14 2017-06-28 Hamlet Pharma Ab Preperation of biologically active complexes
WO2021032807A1 (en) 2019-08-20 2021-02-25 Hamlet Pharma Ab Combination of a chemotherapeutic agent and alpha-lactoglubulin-oleic acid complex for cancer therapy
GB202015836D0 (en) 2020-10-06 2020-11-18 Hamlet Pharma Ab Compositions
GB202303177D0 (en) 2023-03-03 2023-04-19 Linnane Pharma Ab Method of predicting response to treatment
WO2025186107A1 (en) 2024-03-04 2025-09-12 Linnane Pharma Ab Therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008058547A2 (en) * 2006-11-17 2008-05-22 Nya Hamlet Pharma Ab Alpha-lactalbumin composition

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1032596T3 (da) 1997-11-21 2007-09-10 Nya Hamlet Pharma Ab Fremgangsmåde til fremstilling af lactalbumin
GB9725126D0 (en) 1997-11-27 1998-01-28 Svanborg Catharina Therapeutic agents
AU5928599A (en) 1999-09-09 2001-04-10 Efa Sciences Llc. Methods for treating cell proliferative disorders including cancer
US6639089B2 (en) 2000-11-08 2003-10-28 Soda Aromatic Co., Ltd. Anticancer agents, perfumes or foods and drinks
GB0205347D0 (en) 2002-03-07 2002-04-24 Svanborg Catharina Biologically active complex
GB0508880D0 (en) * 2005-05-03 2005-06-08 Hamlet Pharma Ab Novel therapies and methods of screening for therapeutic compounds
US20080115228A1 (en) * 2006-11-15 2008-05-15 Yahoo! Inc. Rights engine
WO2008138348A1 (en) * 2007-05-09 2008-11-20 Nya Hamlet Pharma Ab Preparation of complexed lactalbumin
US8796218B2 (en) 2009-01-09 2014-08-05 Hamlet Pharma Ab Complex and production process
WO2010131237A1 (en) 2009-05-13 2010-11-18 Agriculture And Food Development Authority (Teagasc) A process for producing a biologically active globular protein complex
ES2613986T3 (es) 2010-11-24 2017-05-29 Hamlet Pharma Ab Complejo biológicamente activo y su preparación

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008058547A2 (en) * 2006-11-17 2008-05-22 Nya Hamlet Pharma Ab Alpha-lactalbumin composition

Also Published As

Publication number Publication date
EP2385954B1 (en) 2013-04-03
WO2010079362A1 (en) 2010-07-15
JP5679992B2 (ja) 2015-03-04
CA2752490C (en) 2020-03-10
US20120028883A1 (en) 2012-02-02
DK2385954T3 (da) 2013-06-17
EP2385954A1 (en) 2011-11-16
JP2012514466A (ja) 2012-06-28
AU2010204178A1 (en) 2011-09-01
US8796218B2 (en) 2014-08-05
CN102348721A (zh) 2012-02-08
CA2752490A1 (en) 2010-07-15

Similar Documents

Publication Publication Date Title
AU2010204178B2 (en) Complex and production process
Lees et al. Structure and function of proteolipids in myelin and non-myelin membranes
Gibson et al. Design of peptidyl compounds that affect β-amyloid aggregation: importance of surface tension and context
Le et al. Tolloid cleavage activates latent GDF8 by priming the pro‐complex for dissociation
JPH05501655A (ja) 塩基性線維芽細胞増殖因子の酵素調製法
KR20190092472A (ko) 나노입자 제제
Ramirez et al. Nuclear magnetic resonance-based structural characterization and backbone dynamics of recombinant bee venom melittin
Radicioni et al. Characterization of the cell penetrating properties of a human salivary proline-rich peptide
Fisher et al. Bacterial overexpression, isotope enrichment, and NMR analysis of the N-terminal domain of human apolipoprotein E
Jayaraman et al. Impact of self-association on function of apolipoprotein AI
Francis et al. The single C‐terminal helix of human phospholipid scramblase 1 is required for membrane insertion and scrambling activity
Bascetin et al. Amyloid-like aggregates formation by blood plasma fibronectin
JP5249987B2 (ja) 安定化された水性アルファ−ガラクトシダーゼ組成物およびこれに関連する方法
Dodd et al. Overexpression inEscherichia coli, Folding, Purification, and Characterization of the First Three Short Consensus Repeat Modules of Human Complement Receptor Type 1
JP4233114B2 (ja) フォン・ブィレブランド因子の治療用フラグメント
KR20200038507A (ko) 헤모펙신 제형
Yamaguchi et al. Extension of Aβ2M amyloid fibrils with recombinant human β2-microglobulin
Doucet et al. Gel formation of peptides produced by extensive enzymatic hydrolysis of β-lactoglobulin
Bayley et al. Conformational properties of microtubule protein: Their relation to the self‐assembly process in vitro
Stockner et al. Solution structure of the DNA-binding domain of TraM
Bellmann‐Sickert et al. Selective labelling of stromal cell‐derived factor 1α with carboxyfluorescein to study receptor internalisation
Gao et al. N-terminal deletion effects of human survivin on dimerization and binding to Smac/DIABLO in vitro
JP2020531516A (ja) フォン・ウィルブランド因子のウイルスろ過の方法
Ion et al. SDS-induced Peptide Conformational Changes: From Triglycyl-glycine to Amyloid-β Oligomers Associated with Alzheimer’s Disease
Pawakian The Effects of S-glutathionylation on the Structure and Function of the Mitochondrial Calcium Uniporter (MCU)

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)