AU2009288167B2 - Multispecific antibodies - Google Patents
Multispecific antibodies Download PDFInfo
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- AU2009288167B2 AU2009288167B2 AU2009288167A AU2009288167A AU2009288167B2 AU 2009288167 B2 AU2009288167 B2 AU 2009288167B2 AU 2009288167 A AU2009288167 A AU 2009288167A AU 2009288167 A AU2009288167 A AU 2009288167A AU 2009288167 B2 AU2009288167 B2 AU 2009288167B2
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- sequence
- hvr
- antibody
- seq
- her2
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19085608P | 2008-09-03 | 2008-09-03 | |
| US61/190,856 | 2008-09-03 | ||
| PCT/US2009/055625 WO2010027981A1 (en) | 2008-09-03 | 2009-09-01 | Multispecific antibodies |
Publications (2)
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|---|---|
| AU2009288167A1 AU2009288167A1 (en) | 2010-03-11 |
| AU2009288167B2 true AU2009288167B2 (en) | 2015-10-22 |
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| AU2009288167A Ceased AU2009288167B2 (en) | 2008-09-03 | 2009-09-01 | Multispecific antibodies |
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| US (3) | US8193321B2 (OSRAM) |
| EP (1) | EP2324061B1 (OSRAM) |
| JP (1) | JP5796831B2 (OSRAM) |
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| AU (1) | AU2009288167B2 (OSRAM) |
| BR (1) | BRPI0918648A2 (OSRAM) |
| CA (1) | CA2734905A1 (OSRAM) |
| ES (1) | ES2628108T3 (OSRAM) |
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| MX (1) | MX353984B (OSRAM) |
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| SG (1) | SG193851A1 (OSRAM) |
| TW (1) | TWI487712B (OSRAM) |
| WO (1) | WO2010027981A1 (OSRAM) |
| ZA (1) | ZA201101970B (OSRAM) |
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| US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| US7758859B2 (en) * | 2003-08-01 | 2010-07-20 | Genentech, Inc. | Anti-VEGF antibodies |
| US10118970B2 (en) | 2006-08-30 | 2018-11-06 | Genentech, Inc. | Multispecific antibodies |
| WO2010027981A1 (en) | 2008-09-03 | 2010-03-11 | Genentech, Inc. | Multispecific antibodies |
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| WO2011147986A1 (en) | 2010-05-27 | 2011-12-01 | Genmab A/S | Monoclonal antibodies against her2 |
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