AU2008288241B2 - RNA sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles - Google Patents

RNA sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles Download PDF

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AU2008288241B2
AU2008288241B2 AU2008288241A AU2008288241A AU2008288241B2 AU 2008288241 B2 AU2008288241 B2 AU 2008288241B2 AU 2008288241 A AU2008288241 A AU 2008288241A AU 2008288241 A AU2008288241 A AU 2008288241A AU 2008288241 B2 AU2008288241 B2 AU 2008288241B2
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polymer
immunostimulatory
seq
composition
antigen
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AU2008288241A1 (en
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Marion Jurk
Jorg Heinz Vollmer
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Zoetis Belgium SA
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    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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AU2008288241A 2007-08-13 2008-08-08 RNA sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles Active AU2008288241B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96444807P 2007-08-13 2007-08-13
US60/964,448 2007-08-13
PCT/IB2008/002104 WO2009022216A2 (en) 2007-08-13 2008-08-08 Rna sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles

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AU2008288241A1 AU2008288241A1 (en) 2009-02-19
AU2008288241B2 true AU2008288241B2 (en) 2011-12-01

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EP (1) EP2179039B1 (enExample)
JP (1) JP4847609B2 (enExample)
KR (1) KR20100045508A (enExample)
CN (1) CN101821392B (enExample)
AR (1) AR067928A1 (enExample)
AU (1) AU2008288241B2 (enExample)
BR (1) BRPI0814260B8 (enExample)
CA (1) CA2696630C (enExample)
CL (1) CL2008002371A1 (enExample)
CO (1) CO6260153A2 (enExample)
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JP2010536907A (ja) * 2007-08-31 2010-12-02 ニューリミューン セラピューティクス エイジー 患者にアミロイドーシスおよびタンパク質凝集性障害における特異的免疫応答をもたらす方法
WO2009105641A2 (en) 2008-02-20 2009-08-27 New York University Preventing and treating amyloid-beta deposition by stimulation of innate immunity
WO2013012875A2 (en) 2011-07-18 2013-01-24 Mount Sinai School Of Medicine Bacterial rnas as vaccine adjuvants
WO2015187966A1 (en) 2014-06-04 2015-12-10 Aurasense Therapeutics, Llc Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
WO2016081911A2 (en) 2014-11-21 2016-05-26 Northwestern University The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
WO2018209270A1 (en) 2017-05-11 2018-11-15 Northwestern University Adoptive cell therapy using spherical nucleic acids (snas)
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WO2024030844A1 (en) * 2022-08-01 2024-02-08 University Of Mississippi Choline carboxylic acid based ionic liquids as antimicrobial agents

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US20060074040A1 (en) * 2003-07-15 2006-04-06 Hybridon, Inc. Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
WO2005097993A2 (en) * 2004-02-19 2005-10-20 Coley Pharmaceutical Group, Inc. Immunostimulatory viral rna oligonucleotides
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WO2007062107A2 (en) * 2005-11-25 2007-05-31 Coley Pharmaceutical Gmbh Immunostimulatory oligoribonucleotides

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CN101821392B (zh) 2013-04-17
PL2179039T3 (pl) 2019-03-29
DK2179039T3 (en) 2019-01-07
US8227447B2 (en) 2012-07-24
US20120258140A1 (en) 2012-10-11
US8466124B2 (en) 2013-06-18
CN101821392A (zh) 2010-09-01
US20100272785A1 (en) 2010-10-28
WO2009022216A9 (en) 2009-04-30
BRPI0814260B8 (pt) 2021-05-25
PT2179039T (pt) 2019-01-11
CA2696630C (en) 2014-04-01
RU2010104618A (ru) 2011-09-20
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