AU2008218763B2 - Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix - Google Patents

Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix Download PDF

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Publication number
AU2008218763B2
AU2008218763B2 AU2008218763A AU2008218763A AU2008218763B2 AU 2008218763 B2 AU2008218763 B2 AU 2008218763B2 AU 2008218763 A AU2008218763 A AU 2008218763A AU 2008218763 A AU2008218763 A AU 2008218763A AU 2008218763 B2 AU2008218763 B2 AU 2008218763B2
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AU
Australia
Prior art keywords
pdgf
biocompatible matrix
biocompatible
solution
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008218763A
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English (en)
Other versions
AU2008218763A1 (en
Inventor
Jeffrey O. Hollinger
Samuel E. Lynch
Leslie A. Wisner-Lynch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomimetic Therapeutics LLC
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Biomimetic Therapeutics LLC
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Filing date
Publication date
Application filed by Biomimetic Therapeutics LLC filed Critical Biomimetic Therapeutics LLC
Publication of AU2008218763A1 publication Critical patent/AU2008218763A1/en
Application granted granted Critical
Publication of AU2008218763B2 publication Critical patent/AU2008218763B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
AU2008218763A 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix Ceased AU2008218763B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89076307P 2007-02-20 2007-02-20
US60/890,763 2007-02-20
PCT/US2008/054354 WO2008103690A2 (en) 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix

Publications (2)

Publication Number Publication Date
AU2008218763A1 AU2008218763A1 (en) 2008-08-28
AU2008218763B2 true AU2008218763B2 (en) 2013-10-24

Family

ID=39710710

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008218763A Ceased AU2008218763B2 (en) 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix

Country Status (6)

Country Link
US (1) US20100151025A1 (https=)
EP (1) EP2125000A2 (https=)
JP (1) JP2010518946A (https=)
AU (1) AU2008218763B2 (https=)
CA (1) CA2678875A1 (https=)
WO (1) WO2008103690A2 (https=)

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US8114841B2 (en) 2004-10-14 2012-02-14 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
EP2259807B1 (en) * 2008-02-07 2013-04-24 Biomimetic Therapeutics, Inc. Compositions for distraction osteogenesis
WO2012105223A1 (ja) * 2011-01-31 2012-08-09 オリンパス株式会社 免疫賦活剤
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
GB2549714A (en) * 2016-04-25 2017-11-01 Pharmaceutical Business Consultants Ltd Vascularity affinity precursor structure for musculo-skeletal tissue healing
JP7117724B2 (ja) * 2018-01-18 2022-08-15 新田ゼラチン株式会社 歯肉および歯槽粘膜の再生促進作用に基づく顎骨壊死、顎骨骨髄炎または抜歯後治癒不全の予防に用いる予防剤
WO2025024276A1 (en) * 2023-07-21 2025-01-30 Mercury Bio, Inc. Production and delivery of therapeutic nucleic acids packaged in yeast extracellular vesicles embedded in biocompatible implant matrices

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DE4120325A1 (de) * 1991-06-20 1992-12-24 Merck Patent Gmbh Implantatwerkstoff
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
JP4809963B2 (ja) * 1999-11-11 2011-11-09 オリンパス株式会社 骨補填材
JP2003019195A (ja) * 2000-05-19 2003-01-21 Mmt:Kk 生体用部材
AU2003210996A1 (en) * 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
WO2003094617A2 (en) * 2002-05-06 2003-11-20 Genentech, Inc. Use of vegf for treating bone defects
AU2003245513A1 (en) * 2002-06-14 2003-12-31 Pierce Biotechnology, Inc. Homogenous assay for enzymatic activity
JP2004159971A (ja) * 2002-11-14 2004-06-10 Hideki Yoshikawa 骨形成用部材およびその製造方法
EP1433489A1 (en) * 2002-12-23 2004-06-30 Degradable Solutions AG Biodegradable porous bone implant with a barrier membrane sealed thereto
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JP2005111130A (ja) * 2003-10-10 2005-04-28 Olympus Corp 骨補填材の製造方法
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US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US8114841B2 (en) * 2004-10-14 2012-02-14 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix
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US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
CA2656278C (en) * 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US8106008B2 (en) * 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
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Also Published As

Publication number Publication date
EP2125000A2 (en) 2009-12-02
US20100151025A1 (en) 2010-06-17
CA2678875A1 (en) 2008-08-28
WO2008103690A2 (en) 2008-08-28
JP2010518946A (ja) 2010-06-03
AU2008218763A1 (en) 2008-08-28
WO2008103690A3 (en) 2009-09-03

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired