AU2007275764B2 - Methods for treating pain and screening analgesic compounds - Google Patents
Methods for treating pain and screening analgesic compounds Download PDFInfo
- Publication number
- AU2007275764B2 AU2007275764B2 AU2007275764A AU2007275764A AU2007275764B2 AU 2007275764 B2 AU2007275764 B2 AU 2007275764B2 AU 2007275764 A AU2007275764 A AU 2007275764A AU 2007275764 A AU2007275764 A AU 2007275764A AU 2007275764 B2 AU2007275764 B2 AU 2007275764B2
- Authority
- AU
- Australia
- Prior art keywords
- tyr
- rgia
- iodo
- fluorescent tag
- terminus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/944—Acetylcholine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2014200739A AU2014200739A1 (en) | 2006-07-18 | 2014-02-12 | Methods for treating pain and screening analgesic compounds |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83146806P | 2006-07-18 | 2006-07-18 | |
| US60/831,468 | 2006-07-18 | ||
| PCT/US2007/016163 WO2008011006A2 (en) | 2006-07-18 | 2007-07-17 | Methods for treating pain and screening analgesic compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014200739A Division AU2014200739A1 (en) | 2006-07-18 | 2014-02-12 | Methods for treating pain and screening analgesic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2007275764A1 AU2007275764A1 (en) | 2008-01-24 |
| AU2007275764B2 true AU2007275764B2 (en) | 2013-11-14 |
Family
ID=38957314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007275764A Ceased AU2007275764B2 (en) | 2006-07-18 | 2007-07-17 | Methods for treating pain and screening analgesic compounds |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9717775B2 (enExample) |
| EP (1) | EP2051726B1 (enExample) |
| JP (2) | JP5558817B2 (enExample) |
| AU (1) | AU2007275764B2 (enExample) |
| CA (1) | CA2657532C (enExample) |
| WO (1) | WO2008011006A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9284358B2 (en) | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
| JP5558817B2 (ja) * | 2006-07-18 | 2014-07-23 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 痛みの処置方法および鎮痛化合物のスクリーニング方法 |
| JP6681826B2 (ja) * | 2013-05-31 | 2020-04-15 | ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション | コノトキシンペプチド、医薬組成物およびそれらの使用 |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| EP4393502A2 (en) * | 2018-12-26 | 2024-07-03 | Skinmed Co., Ltd. | Acetylcholine receptor inhibitory peptides and uses thereof |
| US11612661B2 (en) | 2019-01-04 | 2023-03-28 | Kineta Chronic Pain, Llc | Conotoxin peptide analogs and uses for the treatment of pain and inflammatory conditions |
| SG11202106847SA (en) * | 2019-01-04 | 2021-07-29 | Kineta Chronic Pain Llc | Conotoxin peptide analogs and uses for the treatment of pain and inflammatory conditions |
| US12227771B2 (en) | 2019-05-17 | 2025-02-18 | Janssen Pharmaceutica Nv | Expression systems and methods of use thereof |
| CN113493502B (zh) * | 2020-04-01 | 2023-09-12 | 广西大学 | α-芋螺毒素肽TxIE、其药物组合物及用途 |
| EP4378950A4 (en) * | 2021-07-27 | 2025-10-15 | Skinmed Co Ltd | OPTIMIZED SHORTENED PEPTIDE THAT BINDS TO THE ACETYLCHOLINE RECEPTOR, AND ITS USE |
| CN117794942A (zh) * | 2021-07-27 | 2024-03-29 | 思亲美有限公司 | 乙酰胆碱受体结合优化短肽及其用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050215480A1 (en) * | 2001-03-29 | 2005-09-29 | Livett Bruce G | Alpha conotoxin peptides with analgesic properties |
| US6958323B2 (en) * | 1997-12-31 | 2005-10-25 | University of Utah Research Fnd. | Uses of α-conotoxin peptides |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
| US5158881A (en) | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| DE3829766A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
| DE3829752A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration |
| US5082670A (en) | 1988-12-15 | 1992-01-21 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system |
| US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
| SG47470A1 (en) | 1991-04-25 | 1998-04-17 | Univ Brown Res Found | Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products |
| US5854217A (en) | 1992-09-28 | 1998-12-29 | Bearsden Bio, Inc. | Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function |
| WO1994025503A1 (en) | 1993-04-27 | 1994-11-10 | Cytotherapeutics, Inc. | Membrane formed by an acrylonitrile-based polymer |
| AU688776B2 (en) | 1993-06-23 | 1998-03-19 | Brown University Research Foundation | Method and apparatus for sealing implantable, membrane encapsulation devices |
| ES2178654T3 (es) | 1993-08-12 | 2003-01-01 | Neurotech Sa | Capsulas biocompatibles inmonoaisladoras que contienen celulas geneticamente alteradas para el suministro de moleculas biologicamente activas. |
| US5550050A (en) | 1994-04-15 | 1996-08-27 | Cytotherapeutics, Inc. | Method for implanting encapsulated cells in a host |
| US5840576A (en) | 1994-07-20 | 1998-11-24 | Cytotherapeutics, Inc. | Methods and compositions of growth control for cells encapsulated within bioartificial organs |
| US5834029A (en) | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| US5837234A (en) | 1995-06-07 | 1998-11-17 | Cytotherapeutics, Inc. | Bioartificial organ containing cells encapsulated in a permselective polyether suflfone membrane |
| IN181898B (enExample) | 1995-06-07 | 1998-10-24 | Cytotherapeutics Inc | |
| WO1997012635A1 (en) | 1995-10-02 | 1997-04-10 | Cytotherapeutics, Inc. | Method for treating amyotrophic lateral sclerosis |
| WO1997035478A1 (en) * | 1996-03-26 | 1997-10-02 | The Regents Of The University Of California | Selective target cell activation by expression of a g protein-coupled receptor activated superiorly by synthetic ligand |
| US5844077A (en) | 1997-04-28 | 1998-12-01 | Cytotherapeutics, Inc. | Use of conantokins for producing analgesia or for neuroprotection |
| AU3473800A (en) * | 1999-01-29 | 2000-08-18 | University Of Utah Research Foundation | Conotoxin peptides |
| JP2002534996A (ja) * | 1999-01-29 | 2002-10-22 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション | アルファ−コノトキシン・ペプチド |
| AU780460B2 (en) * | 1999-09-15 | 2005-03-24 | Janssen Pharmaceutica N.V. | Nicotinic acetylcholine receptor alpha10 subunit |
| EP1090991A1 (en) * | 1999-09-29 | 2001-04-11 | Sanofi-Synthelabo | Novel nicotinic acetylcholine receptor subunit, its isolation and use |
| US20030109670A1 (en) * | 2001-02-09 | 2003-06-12 | University Of Utah Research Foundation | Cone snail peptides |
| US20110092448A1 (en) * | 2005-08-02 | 2011-04-21 | Metabolic Pharmaceuticals Limited | Peptide Conjugate for Oral Delivery of Hydrophilic Peptide Analgesics |
| AU2006236006B2 (en) * | 2006-04-13 | 2012-09-06 | The University Of Queensland | Cyclised a-conotoxin peptides |
| JP5558817B2 (ja) * | 2006-07-18 | 2014-07-23 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 痛みの処置方法および鎮痛化合物のスクリーニング方法 |
| US9284358B2 (en) | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
-
2007
- 2007-07-17 JP JP2009520801A patent/JP5558817B2/ja not_active Expired - Fee Related
- 2007-07-17 CA CA2657532A patent/CA2657532C/en not_active Expired - Fee Related
- 2007-07-17 AU AU2007275764A patent/AU2007275764B2/en not_active Ceased
- 2007-07-17 US US12/307,953 patent/US9717775B2/en active Active - Reinstated
- 2007-07-17 WO PCT/US2007/016163 patent/WO2008011006A2/en not_active Ceased
- 2007-07-17 EP EP07796903.8A patent/EP2051726B1/en not_active Not-in-force
-
2014
- 2014-06-05 JP JP2014116680A patent/JP5953338B2/ja not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6958323B2 (en) * | 1997-12-31 | 2005-10-25 | University of Utah Research Fnd. | Uses of α-conotoxin peptides |
| US20050215480A1 (en) * | 2001-03-29 | 2005-09-29 | Livett Bruce G | Alpha conotoxin peptides with analgesic properties |
Non-Patent Citations (2)
| Title |
|---|
| J. M. MCINTOSH: "A Novel-Conotoxin, PeIA, Cloned from Conus pergrandis, Discriminates between Rat 9 10 and 7 Nicotinic Cholinergic Receptors", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, no. 34,1 January 2005 (2005-01-01), pages 30107-30112, * |
| Johnson D.S. et al. Molecular Pharmacology, 1995, vol. 48, pages 194-199 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5953338B2 (ja) | 2016-07-20 |
| US9717775B2 (en) | 2017-08-01 |
| EP2051726B1 (en) | 2018-04-18 |
| JP2009545526A (ja) | 2009-12-24 |
| US20090203616A1 (en) | 2009-08-13 |
| EP2051726A2 (en) | 2009-04-29 |
| JP2014210784A (ja) | 2014-11-13 |
| JP5558817B2 (ja) | 2014-07-23 |
| CA2657532A1 (en) | 2008-01-24 |
| WO2008011006A3 (en) | 2008-06-19 |
| WO2008011006A2 (en) | 2008-01-24 |
| AU2007275764A1 (en) | 2008-01-24 |
| EP2051726A4 (en) | 2012-06-20 |
| CA2657532C (en) | 2019-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |