AU2007275686B2 - Thiadiazolidinone derivatives - Google Patents
Thiadiazolidinone derivatives Download PDFInfo
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- AU2007275686B2 AU2007275686B2 AU2007275686A AU2007275686A AU2007275686B2 AU 2007275686 B2 AU2007275686 B2 AU 2007275686B2 AU 2007275686 A AU2007275686 A AU 2007275686A AU 2007275686 A AU2007275686 A AU 2007275686A AU 2007275686 B2 AU2007275686 B2 AU 2007275686B2
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
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| US83189306P | 2006-07-18 | 2006-07-18 | |
| US60/831,893 | 2006-07-18 | ||
| PCT/US2007/016391 WO2008011113A2 (en) | 2006-07-18 | 2007-07-18 | Thiadiazolidinone derivatives |
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| EP2043633B1 (en) * | 2006-07-18 | 2016-07-06 | University of Rochester | Thiadiazolidinone derivatives for treating cancer |
| WO2009058394A1 (en) * | 2007-11-01 | 2009-05-07 | Celgene Corporation | Cytidine analogs for treatment of myelodysplastic syndromes |
| US20090117090A1 (en) * | 2007-11-01 | 2009-05-07 | Ottawa Heart Institute Research Corporation | Inhibition of glycogen synthase kinase 3 beta in arterial repair and stent re-endothelialization |
| WO2011151359A1 (en) * | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
| JP6998657B2 (ja) | 2013-09-18 | 2022-02-04 | エピアクシス セラピューティクス プロプライエタリー リミテッド | 幹細胞調節ｉｉ |
| AU2015274334B2 (en) * | 2014-06-12 | 2020-12-17 | Cedars-Sinai Medical Center | Compositions and methods for treating cancers |
| JP6534098B2 (ja) * | 2014-09-12 | 2019-06-26 | 国立大学法人 鹿児島大学 | 成人ｔ細胞白血病治療薬 |
| KR20170129769A (ko) | 2015-03-17 | 2017-11-27 | 리제너론 파아마슈티컬스, 인크. | 아미노산 아실화 시약 및 이의 사용 방법 |
| CN109715166A (zh) * | 2016-07-14 | 2019-05-03 | 深圳明赛瑞霖药业有限公司 | 癌症的治疗 |
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| WO2001085685A1 (en) * | 2000-05-11 | 2001-11-15 | Consejo Superior Investigaciones Cientificas | Heterocyclic inhibitors of glycogen synthase kinase gsk-3 |
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| AU1507799A (en) | 1997-12-16 | 1999-07-05 | Sankyo Company Limited | Leukemia remedy |
| JPH11335298A (ja) * | 1997-12-16 | 1999-12-07 | Sankyo Co Ltd | 白血病治療剤 |
| AU2001248365A1 (en) | 2000-03-23 | 2001-10-03 | Mitsubishi Pharma Corporation | 2-(arylalkylamino)pyrimidone derivatives and 2-(heteroarylalkylamino)pyrimidone derivatives |
| ES2166328B1 (es) * | 2000-05-11 | 2003-09-16 | Consejo Superior Investigacion | Inhibidores heterociclicos del enzima gsk 3 utiles en el tratamiento de procesos neurodegenerativos e hiperproliferativos |
| EP1586318A1 (en) * | 2004-04-05 | 2005-10-19 | Neuropharma S.A.U. | Thiadiazolidinones as GSK-3 inhibitors |
| FI20041129A0 (fi) * | 2004-08-30 | 2004-08-30 | Ctt Cancer Targeting Tech Oy | Tioksotiatsolidinoniyhdisteitä lääkkeinä käytettäviksi |
| WO2006045581A1 (en) * | 2004-10-21 | 2006-05-04 | Neuropharma, S.A. | The use of 1, 2, 4-thiadiazolidine-3, 5-diones as ppar activators |
| US20060204980A1 (en) * | 2004-12-28 | 2006-09-14 | Altieri Dario C | Colorectal cancer therapies |
| US20070196514A1 (en) * | 2006-02-21 | 2007-08-23 | Benyi Li | Prostate cancer treatment with glycogen synthase kinase-3beta inhibitors |
| EP2043633B1 (en) * | 2006-07-18 | 2016-07-06 | University of Rochester | Thiadiazolidinone derivatives for treating cancer |
-
2007
- 2007-07-18 EP EP07810619.2A patent/EP2043633B1/en not_active Not-in-force
- 2007-07-18 US US12/374,002 patent/US9180118B2/en not_active Expired - Fee Related
- 2007-07-18 NZ NZ574619A patent/NZ574619A/en not_active IP Right Cessation
- 2007-07-18 AU AU2007275686A patent/AU2007275686B2/en not_active Ceased
- 2007-07-18 JP JP2009520840A patent/JP2009543874A/ja active Pending
- 2007-07-18 WO PCT/US2007/016391 patent/WO2008011113A2/en not_active Ceased
- 2007-07-18 CA CA002658263A patent/CA2658263A1/en not_active Abandoned
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2015
- 2015-10-08 US US14/878,330 patent/US20160058741A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001085685A1 (en) * | 2000-05-11 | 2001-11-15 | Consejo Superior Investigaciones Cientificas | Heterocyclic inhibitors of glycogen synthase kinase gsk-3 |
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| Publication number | Publication date |
|---|---|
| US20100063109A1 (en) | 2010-03-11 |
| JP2009543874A (ja) | 2009-12-10 |
| WO2008011113A2 (en) | 2008-01-24 |
| EP2043633A4 (en) | 2009-11-25 |
| EP2043633A2 (en) | 2009-04-08 |
| US9180118B2 (en) | 2015-11-10 |
| CA2658263A1 (en) | 2008-01-24 |
| AU2007275686A1 (en) | 2008-01-24 |
| EP2043633B1 (en) | 2016-07-06 |
| WO2008011113A3 (en) | 2008-02-28 |
| NZ574619A (en) | 2012-03-30 |
| US20160058741A1 (en) | 2016-03-03 |
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