AU2007235517B2 - Use of rasagiline for the treatment of Restless Legs Syndrome - Google Patents

Use of rasagiline for the treatment of Restless Legs Syndrome Download PDF

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Publication number
AU2007235517B2
AU2007235517B2 AU2007235517A AU2007235517A AU2007235517B2 AU 2007235517 B2 AU2007235517 B2 AU 2007235517B2 AU 2007235517 A AU2007235517 A AU 2007235517A AU 2007235517 A AU2007235517 A AU 2007235517A AU 2007235517 B2 AU2007235517 B2 AU 2007235517B2
Authority
AU
Australia
Prior art keywords
propargyl
aminoindan
pharmaceutically acceptable
subject
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007235517A
Other languages
English (en)
Other versions
AU2007235517A1 (en
Inventor
Eran Blaugrund
Ruth Levy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of AU2007235517A1 publication Critical patent/AU2007235517A1/en
Application granted granted Critical
Publication of AU2007235517B2 publication Critical patent/AU2007235517B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AU2007235517A 2006-04-03 2007-03-30 Use of rasagiline for the treatment of Restless Legs Syndrome Ceased AU2007235517B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78861706P 2006-04-03 2006-04-03
US60/788,617 2006-04-03
PCT/US2007/008261 WO2007117431A2 (en) 2006-04-03 2007-03-30 Use of rasagiline for the treatment of restless legs syndrome

Publications (2)

Publication Number Publication Date
AU2007235517A1 AU2007235517A1 (en) 2007-10-18
AU2007235517B2 true AU2007235517B2 (en) 2013-01-31

Family

ID=38581572

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007235517A Ceased AU2007235517B2 (en) 2006-04-03 2007-03-30 Use of rasagiline for the treatment of Restless Legs Syndrome

Country Status (11)

Country Link
US (16) US8946300B2 (cg-RX-API-DMAC10.html)
EP (1) EP2007369A4 (cg-RX-API-DMAC10.html)
JP (2) JP5769923B2 (cg-RX-API-DMAC10.html)
CN (1) CN101442997B (cg-RX-API-DMAC10.html)
AU (1) AU2007235517B2 (cg-RX-API-DMAC10.html)
CA (1) CA2646250A1 (cg-RX-API-DMAC10.html)
IL (5) IL194328A (cg-RX-API-DMAC10.html)
MX (1) MX2008012781A (cg-RX-API-DMAC10.html)
NZ (1) NZ571591A (cg-RX-API-DMAC10.html)
WO (1) WO2007117431A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200808409B (cg-RX-API-DMAC10.html)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060018957A1 (en) * 2004-07-26 2006-01-26 Lerner E I Pharmaceutical dosage forms including rasagiline
RS52867B (sr) * 2005-02-17 2013-12-31 Teva Pharmaceutical Industries Ltd. Kombinovana terapija glatiramer acetatom i razagilinom za lečenje multiple skleroze
US7815942B2 (en) 2005-02-23 2010-10-19 Teva Pharmaceutical Industries, Ltd. Rasagiline formulations of improved content uniformity
US7491847B2 (en) * 2005-11-17 2009-02-17 Teva Pharmaceutical Industries, Ltd. Methods for isolating propargylated aminoindans
US7572834B1 (en) 2005-12-06 2009-08-11 Teva Pharmaceutical Industries, Ltd. Rasagiline formulations and processes for their preparation
US8809310B2 (en) 2006-02-21 2014-08-19 Teva Pharmaceutical Industries, Ltd. Use of rasagiline for the treatment of multiple system atrophy
AU2007235517B2 (en) 2006-04-03 2013-01-31 Teva Pharmaceutical Industries, Ltd. Use of rasagiline for the treatment of Restless Legs Syndrome
EP1892233A1 (de) 2006-08-18 2008-02-27 Ratiopharm GmbH Neue Salze des Wirkstoffs Rasagilin
AU2007334428B2 (en) 2006-12-14 2014-05-29 Teva Pharmaceutical Industries, Ltd. Crystalline solid rasagiline base
UA97382C2 (ru) * 2006-12-14 2012-02-10 Тева Фармасьютікл Індастріз, Лтд. Таннат разагилина
EP1987816A1 (de) * 2007-04-30 2008-11-05 Ratiopharm GmbH Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff
US20090062400A1 (en) * 2007-09-05 2009-03-05 Laurence Oron Method of treating glaucoma using rasagiline
US8188149B2 (en) * 2007-09-17 2012-05-29 Teva Pharmaceutical Industries, Ltd. Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss
RU2540470C9 (ru) 2008-06-06 2015-07-20 Фарма Ту Б Лтд. Фармацевтические композиции для лечения болезни паркинсона
AU2009258120B2 (en) * 2008-06-10 2014-11-27 Teva Pharmaceutical Industries, Ltd. Rasagiline soft gelatin capsules
EP2296462A4 (en) * 2008-06-13 2011-06-15 Teva Pharma RASAGILINE FOR INFLUENCING MORBUS PARKINSON
JP2011525489A (ja) * 2008-06-19 2011-09-22 テバ ファーマシューティカル インダストリーズ リミティド ラサリジン塩基の精製方法
NZ589547A (en) 2008-06-19 2013-03-28 Teva Pharma Dried rasagiline base having a water content less than 0.5 % by weight
US20100189790A1 (en) * 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline formulation
PT2451771E (pt) 2009-07-09 2014-09-19 Ratiopharm Gmbh Sais de rasagilina e suas preparações farmacêuticas
RU2587330C2 (ru) 2010-07-27 2016-06-20 Тева Фармасьютикал Индастриз Лтд. Применение разагилина для лечения обонятельной дисфункции
WO2012015946A1 (en) 2010-07-27 2012-02-02 Teva Pharmaceutical Industries Ltd. Dispersion of rasagiline citrate
CA2851433A1 (en) 2011-10-10 2013-04-18 Teva Pharmaceutical Industries Ltd. R(+)-n-methyl-propargyl-aminoindan
BR112014008555A2 (pt) 2011-10-10 2017-04-18 Teva Pharma r(+)-n-formil-propargil-aminoindano
JP6243351B2 (ja) * 2012-01-12 2017-12-06 ファーマ ツゥ ビー リミテッド パーキンソン病の固定投与量薬剤組合せ治療
AR092168A1 (es) * 2012-08-17 2015-03-25 Teva Pharma Formulaciones parenterales de rasagilina
RS65663B1 (sr) 2018-02-15 2024-07-31 Intrabio Ltd Acetil leucin za upotrebu u lečenju sindroma nemirnih nogu

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AU2006327254A1 (en) * 2005-12-20 2007-06-28 Cereuscience Ab Method and composition for treating and diagnosing restless legs syndrome
AU2007222825A1 (en) * 2006-03-06 2007-09-13 Chongqing Pharmaceutical Research Institute Co., Ltd. Transdermal patch containing rasagiline for treatment or prophylaxis of nervous system disease and its preparation process

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AU2006327254A1 (en) * 2005-12-20 2007-06-28 Cereuscience Ab Method and composition for treating and diagnosing restless legs syndrome
AU2007222825A1 (en) * 2006-03-06 2007-09-13 Chongqing Pharmaceutical Research Institute Co., Ltd. Transdermal patch containing rasagiline for treatment or prophylaxis of nervous system disease and its preparation process

Also Published As

Publication number Publication date
CA2646250A1 (en) 2007-10-18
US20150080441A1 (en) 2015-03-19
US20170360723A1 (en) 2017-12-21
IL247850A0 (en) 2016-11-30
US20190262284A1 (en) 2019-08-29
US20210137852A1 (en) 2021-05-13
IL234749A0 (en) 2014-11-30
US20210023026A1 (en) 2021-01-28
CN101442997A (zh) 2009-05-27
US20200206161A1 (en) 2020-07-02
IL265866A (en) 2019-06-30
JP5769923B2 (ja) 2015-08-26
AU2007235517A1 (en) 2007-10-18
US20210386690A1 (en) 2021-12-16
IL275890A (en) 2020-08-31
WO2007117431A3 (en) 2008-11-27
US20190142766A1 (en) 2019-05-16
WO2007117431A2 (en) 2007-10-18
US20180169038A1 (en) 2018-06-21
NZ571591A (en) 2011-09-30
US20190365674A1 (en) 2019-12-05
CN101442997B (zh) 2012-11-14
JP2013166772A (ja) 2013-08-29
US20210251921A1 (en) 2021-08-19
US20070232700A1 (en) 2007-10-04
US8946300B2 (en) 2015-02-03
ZA200808409B (en) 2009-12-30
EP2007369A4 (en) 2009-07-01
US20190000780A1 (en) 2019-01-03
US20160317471A1 (en) 2016-11-03
US20200323796A1 (en) 2020-10-15
US20200093758A1 (en) 2020-03-26
EP2007369A2 (en) 2008-12-31
IL194328A (en) 2017-11-30
MX2008012781A (es) 2008-10-14
JP2009534312A (ja) 2009-09-24
US12310929B2 (en) 2025-05-27

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