AU2007218025A1 - HIV fusion inhibitor peptides with improved biological properties - Google Patents
HIV fusion inhibitor peptides with improved biological properties Download PDFInfo
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- AU2007218025A1 AU2007218025A1 AU2007218025A AU2007218025A AU2007218025A1 AU 2007218025 A1 AU2007218025 A1 AU 2007218025A1 AU 2007218025 A AU2007218025 A AU 2007218025A AU 2007218025 A AU2007218025 A AU 2007218025A AU 2007218025 A1 AU2007218025 A1 AU 2007218025A1
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- seq
- peptide
- hiv
- amino acid
- fusion inhibitor
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US76467406P | 2006-02-02 | 2006-02-02 | |
| US60/764,674 | 2006-02-02 | ||
| PCT/US2007/002990 WO2007097903A2 (en) | 2006-02-02 | 2007-02-02 | Hiv fusion inhibitor peptides with improved biological properties |
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| AU2007218025A1 true AU2007218025A1 (en) | 2007-08-30 |
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| EP (1) | EP1989220B1 (enExample) |
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| AR (2) | AR059300A1 (enExample) |
| AT (1) | ATE537183T1 (enExample) |
| AU (1) | AU2007218025A1 (enExample) |
| CA (1) | CA2651793C (enExample) |
| CY (1) | CY1113115T1 (enExample) |
| DK (1) | DK1989220T3 (enExample) |
| ES (1) | ES2381631T3 (enExample) |
| NZ (1) | NZ570300A (enExample) |
| PT (1) | PT1989220E (enExample) |
| TW (1) | TWI341844B (enExample) |
| WO (1) | WO2007097903A2 (enExample) |
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| AU2007218025A1 (en) | 2006-02-02 | 2007-08-30 | Trimeris, Inc. | HIV fusion inhibitor peptides with improved biological properties |
| BRPI0817697A2 (pt) * | 2007-09-25 | 2015-04-07 | Trimeris Inc | Método de síntese de um peptídeo, conjunto de fragmentos de peptídeo, e, peptídeo |
| AU2009260479A1 (en) * | 2008-05-28 | 2009-12-23 | New York Blood Center | Bifunctional molecules for inhibiting HIV entry |
| AU2009281992A1 (en) * | 2008-08-13 | 2010-02-18 | New York Blood Center | Combination therapy of HIV fusion/entry inhibitors targeting gp41 |
| US8936789B2 (en) * | 2008-10-16 | 2015-01-20 | New York Bood Center, Inc. | Immunoenhancer-linked oligomeric HIV envelope peptides |
| WO2010047826A2 (en) * | 2008-10-24 | 2010-04-29 | Trimeris, Inc. | Dosing regimens and dosage formulations of an antiviral peptide therapeutic |
| WO2010091373A2 (en) * | 2009-02-09 | 2010-08-12 | New York Blood Center, Inc. | Trimeric hiv fusion inhibitors for treating or preventing hiv infection |
| EP2566493B1 (en) | 2010-05-03 | 2015-03-04 | New York Blood Center, Inc. | Bifunctional molecules for inactivating hiv and blocking hiv |
| RU2014129907A (ru) * | 2011-12-19 | 2016-02-10 | ЯНССЕН Ар ЭНД Ди АЙРЛЭНД | Ингибиторы слияния hiv с мембраной |
| US20150045291A1 (en) | 2012-04-04 | 2015-02-12 | Yeda Research And Development Co., Ltd. | Lipopeptide conjugates comprising sphingolipid and hiv gp41 derived peptides |
| CN103724404B (zh) * | 2013-12-08 | 2016-11-02 | 北京工业大学 | 抑制hiv病毒与宿主细胞融合的非对映体多肽及其用途 |
| GB201509782D0 (en) * | 2015-06-05 | 2015-07-22 | Isis Innovation | Methods and products for fusion protein synthesis |
| CN109320593A (zh) * | 2018-11-05 | 2019-02-12 | 中国人民解放军军事科学院军事医学研究院 | 抑制hiv感染的螺旋多肽及其用途 |
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| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4530840A (en) | 1982-07-29 | 1985-07-23 | The Stolle Research And Development Corporation | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents |
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| US4629783A (en) | 1985-04-29 | 1986-12-16 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
| US5234520A (en) | 1987-03-20 | 1993-08-10 | Morgan Adhesives Co. | Method of making an adhesive construction |
| CN1030256A (zh) * | 1987-06-29 | 1989-01-11 | 日清食品株式会社 | 检测和治疗人类免疫缺陷病毒的方法和物质 |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
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| AU2791792A (en) | 1991-10-04 | 1993-05-03 | Robert H. Cornett | Approaching emergency vehicle warning system |
| WO1994002505A1 (en) | 1992-07-20 | 1994-02-03 | Duke University | Compounds which inhibit hiv replication |
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| US6004549A (en) | 1994-12-14 | 1999-12-21 | Schering Corporation | Crystalline protein controlled release compositions |
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| CN1100564C (zh) | 2001-08-29 | 2003-02-05 | 周根发 | 用于治疗hiv感染的药物、其组合物及其用途 |
| US7045552B2 (en) | 2002-09-27 | 2006-05-16 | Trimeris, Inc. | Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy |
| JP2007517522A (ja) * | 2004-01-07 | 2007-07-05 | トリメリス，インコーポレーテッド | ＨＩＶｇｐ４１ＨＲ２由来の合成ペプチド、およびヒト免疫不全ウイルスの伝播を阻止する治療におけるその使用 |
| CN101132812A (zh) | 2004-03-15 | 2008-02-27 | 阿拉巴马耐科塔医药公司 | Hiv进入抑制剂的聚合物基组合物和结合物 |
| JP2007529522A (ja) * | 2004-03-15 | 2007-10-25 | トリメリス，インコーポレーテッド | ＨＩＶｇｐ４１由来ペプチドの部位特異的化学修飾 |
| AU2007218025A1 (en) | 2006-02-02 | 2007-08-30 | Trimeris, Inc. | HIV fusion inhibitor peptides with improved biological properties |
-
2007
- 2007-02-02 AU AU2007218025A patent/AU2007218025A1/en not_active Abandoned
- 2007-02-02 ES ES07749903T patent/ES2381631T3/es active Active
- 2007-02-02 CN CN200780011992.6A patent/CN101415723B/zh not_active Expired - Fee Related
- 2007-02-02 WO PCT/US2007/002990 patent/WO2007097903A2/en not_active Ceased
- 2007-02-02 US US11/701,910 patent/US7456251B2/en active Active
- 2007-02-02 EP EP07749903A patent/EP1989220B1/en active Active
- 2007-02-02 PT PT07749903T patent/PT1989220E/pt unknown
- 2007-02-02 DK DK07749903.6T patent/DK1989220T3/da active
- 2007-02-02 CA CA2651793A patent/CA2651793C/en not_active Expired - Fee Related
- 2007-02-02 TW TW096104190A patent/TWI341844B/zh not_active IP Right Cessation
- 2007-02-02 JP JP2008553389A patent/JP4682251B2/ja not_active Expired - Fee Related
- 2007-02-02 AT AT07749903T patent/ATE537183T1/de active
- 2007-02-02 NZ NZ570300A patent/NZ570300A/en not_active IP Right Cessation
- 2007-02-02 AR ARP070100450A patent/AR059300A1/es active IP Right Grant
-
2008
- 2008-10-20 US US12/254,259 patent/US8034899B2/en active Active
-
2011
- 2011-08-31 US US13/222,766 patent/US20120040891A1/en not_active Abandoned
-
2012
- 2012-03-14 CY CY20121100268T patent/CY1113115T1/el unknown
-
2017
- 2017-05-02 AR ARP170101125A patent/AR108277A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101415723A (zh) | 2009-04-22 |
| US20070179278A1 (en) | 2007-08-02 |
| TW200806687A (en) | 2008-02-01 |
| EP1989220A4 (en) | 2009-05-06 |
| US7456251B2 (en) | 2008-11-25 |
| AR059300A1 (es) | 2008-03-26 |
| CA2651793A1 (en) | 2007-08-30 |
| EP1989220B1 (en) | 2011-12-14 |
| CY1113115T1 (el) | 2016-04-13 |
| ES2381631T3 (es) | 2012-05-30 |
| AR108277A2 (es) | 2018-08-01 |
| US20120040891A1 (en) | 2012-02-16 |
| ATE537183T1 (de) | 2011-12-15 |
| CA2651793C (en) | 2015-07-07 |
| JP4682251B2 (ja) | 2011-05-11 |
| DK1989220T3 (da) | 2012-04-02 |
| PT1989220E (pt) | 2012-03-23 |
| TWI341844B (en) | 2011-05-11 |
| US8034899B2 (en) | 2011-10-11 |
| US20090105143A1 (en) | 2009-04-23 |
| CN101415723B (zh) | 2014-06-25 |
| WO2007097903A3 (en) | 2008-05-22 |
| WO2007097903A2 (en) | 2007-08-30 |
| EP1989220A2 (en) | 2008-11-12 |
| NZ570300A (en) | 2011-08-26 |
| JP2009525051A (ja) | 2009-07-09 |
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