AU2007215218B2 - Variants in complement regulatory genes predict age-related macular degeneration - Google Patents
Variants in complement regulatory genes predict age-related macular degeneration Download PDFInfo
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US77298906P | 2006-02-13 | 2006-02-13 | |
US60/772,989 | 2006-02-13 | ||
PCT/US2007/003696 WO2007095185A2 (fr) | 2006-02-13 | 2007-02-13 | Variants de genes de regulation du complement permettant de predire la degenerescence maculaire liee a l'age |
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CA (1) | CA2638916A1 (fr) |
IL (1) | IL193396A (fr) |
NZ (1) | NZ570431A (fr) |
WO (1) | WO2007095185A2 (fr) |
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US8012683B2 (en) | 2006-02-13 | 2011-09-06 | University Of Iowa Research Foundation | Variants in complement regulatory genes predict age-related macular degeneration |
US20120141994A1 (en) * | 2009-04-29 | 2012-06-07 | Deangelis Margaret M | Methods and compositions for prognosing and detecting age-related macular degeneration |
EP2963128A1 (fr) * | 2009-07-10 | 2016-01-06 | The Regents of the University of Michigan | Compositions et procédés pour le diagnostic et le traitement de la dégénérescence maculaire |
WO2011053774A1 (fr) * | 2009-10-30 | 2011-05-05 | Alcon Research, Ltd. | Polymorphismes simple nucléotide et gènes associés à la dégénérescence maculaire liée à l'âge |
US9056874B2 (en) | 2012-05-04 | 2015-06-16 | Novartis Ag | Complement pathway modulators and uses thereof |
CN102707068B (zh) * | 2012-05-31 | 2015-03-18 | 北京大学 | 补体h因子用作甲基苯丙胺成瘾患者的基因表达产物中的应用 |
JP6387391B2 (ja) | 2013-03-14 | 2018-09-05 | ノバルティス アーゲー | 眼科疾患の処置に有用な補体因子B阻害剤としての2−(1H−インドール−4−イルメチル)−3H−イミダゾ[4,5−b]ピリジン−6−カルボニトリル誘導体 |
US9676728B2 (en) | 2013-10-30 | 2017-06-13 | Novartis Ag | 2-benzyl-benzimidazole complement factor B inhibitors and uses thereof |
US20170073754A1 (en) * | 2014-02-07 | 2017-03-16 | Novartis Ag | Impact of genetic factors on disease progression and response to anti-c5 antibody in geographic atrophy |
CN106999559A (zh) * | 2014-12-19 | 2017-08-01 | 儿童医院医疗中心 | 与移植相关血栓性微血管病相关的方法和组合物 |
CN109082460B (zh) * | 2018-09-27 | 2021-07-13 | 领航基因科技(杭州)有限公司 | 应用于snp分型的非竞争性探针设计方法、检测方法及应用 |
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WO1985001051A1 (fr) | 1983-09-02 | 1985-03-14 | Molecular Biosystems, Inc. | Systeme de support polymere d'oligonucleotides |
GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
DE69503126T2 (de) | 1994-05-05 | 1998-11-12 | Beckman Instruments Inc | Repetitive oligonukleotide matrix |
US5985567A (en) | 1997-08-15 | 1999-11-16 | Beckman Coulter, Inc. | Hybridization detection by pretreating bound single-stranded probes |
US6013789A (en) | 1998-02-20 | 2000-01-11 | Beckman Coulter, Inc. | Covalent attachment of biomolecules to derivatized polypropylene supports |
WO2006062716A2 (fr) * | 2004-11-18 | 2006-06-15 | Yale University | Methodes et preparations pour le traitement de troubles oculaires |
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2007
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- 2007-02-13 WO PCT/US2007/003696 patent/WO2007095185A2/fr active Application Filing
- 2007-02-13 CA CA002638916A patent/CA2638916A1/fr not_active Abandoned
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Hageman et al, (2005) PNAS v102 p7227-32 * |
Also Published As
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CN101421409A (zh) | 2009-04-29 |
JP5290772B2 (ja) | 2013-09-18 |
IL193396A0 (en) | 2009-05-04 |
NZ570431A (en) | 2011-12-22 |
EP1989319A2 (fr) | 2008-11-12 |
CA2638916A1 (fr) | 2007-08-23 |
AU2007215218A1 (en) | 2007-08-23 |
JP2009526524A (ja) | 2009-07-23 |
WO2007095185A3 (fr) | 2008-09-25 |
EP1989319A4 (fr) | 2009-11-11 |
WO2007095185A2 (fr) | 2007-08-23 |
IL193396A (en) | 2013-03-24 |
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