AU2007213670A1 - 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors - Google Patents

3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors Download PDF

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Publication number
AU2007213670A1
AU2007213670A1 AU2007213670A AU2007213670A AU2007213670A1 AU 2007213670 A1 AU2007213670 A1 AU 2007213670A1 AU 2007213670 A AU2007213670 A AU 2007213670A AU 2007213670 A AU2007213670 A AU 2007213670A AU 2007213670 A1 AU2007213670 A1 AU 2007213670A1
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Prior art keywords
disorder
pain
diaza
bicyclo
quinolin
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Abandoned
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AU2007213670A
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English (en)
Inventor
Elsebet Ostergaard Nielsen
Dan Peters
John Paul Redrobe
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
AU2007213670A 2006-02-10 2007-02-09 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors Abandoned AU2007213670A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77188906P 2006-02-10 2006-02-10
DKPA200600191 2006-02-10
DKPA200600191 2006-02-10
US60/771,889 2006-02-10
PCT/EP2007/051271 WO2007090887A1 (en) 2006-02-10 2007-02-09 3, 9-diazabicyclo [3.3. 1]nonane derivatives and their use as monoamine?neurotransmitter re-uptake inhibitors

Publications (1)

Publication Number Publication Date
AU2007213670A1 true AU2007213670A1 (en) 2007-08-16

Family

ID=37909418

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007213670A Abandoned AU2007213670A1 (en) 2006-02-10 2007-02-09 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Country Status (6)

Country Link
US (1) US7687517B2 (enExample)
EP (1) EP1984366B1 (enExample)
JP (1) JP2009526023A (enExample)
AU (1) AU2007213670A1 (enExample)
CA (1) CA2641683A1 (enExample)
WO (1) WO2007090887A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009526024A (ja) 2006-02-10 2009-07-16 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体アゴニストとしての３−ヘテロアリール−３，９−ジアザビシクロ［３．３．１］ノナン誘導体
US7700596B2 (en) 2006-02-10 2010-04-20 Neurosearch A/S 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP2288609A2 (en) * 2008-06-10 2011-03-02 NeuroSearch A/S Indolyl-pyridazinyl-diazabicyclononane derivatives in labelled and unlabelled form and their use in diagnostic methods

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196154A (en) 1962-05-17 1965-07-20 Sterling Drug Inc 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes
IN166416B (enExample) 1985-09-18 1990-05-05 Pfizer
US5478939A (en) 1994-07-20 1995-12-26 American Cyanamid Company (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives
JP2002502383A (ja) 1997-05-30 2002-01-22 ニューロサーアチ・アクティーゼルスカブ ニコチンＡＣｈレセプターに於けるコリン作動性リガンドとしての９−アザビシクロ（３．３．１）ノン−２−エン及びノナン誘導体
TR199902942T2 (xx) 1997-05-30 2000-04-21 Neurosearch A/S Nikotinik ACh Resept�rlerinde kolinerjik ligandlar olarak 8-Azabisiklo(3.2.1)okt-ene ve okstan t�revleri.
DE69919436T2 (de) 1998-04-16 2005-09-15 Pfizer Products Inc., Groton N-Acyl und N-Aroyl Aralkylamide
FR2786770B1 (fr) 1998-12-04 2001-01-19 Synthelabo Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique
US7265115B2 (en) 1999-01-29 2007-09-04 Abbott Laboratories Diazabicyclic CNS active agents
CN1345320A (zh) 1999-01-29 2002-04-17 艾博特公司 用作烟碱性乙酰胆碱受体配体的二氮杂二环衍生物
DE60008866T2 (de) * 1999-05-04 2005-01-27 Neurosearch A/S Heteroaryl diazabicycloalkene, deren herstellung und verwendung
JP2003534344A (ja) 2000-05-25 2003-11-18 ターガセプト，インコーポレイテッド ニコチン性コリン受容体リガンドとしてのヘテロアリールジアザビシクロアルカン
WO2002002564A1 (en) 2000-07-04 2002-01-10 Neurosearch A/S Aryl and heteroaryl diazabicycloalkanes, their preparation and use
DE60203007T2 (de) 2001-06-01 2005-07-07 Neurosearch A/S Heteroaryl-diazabicycloalkanderivaten als cns-modulatoren
US7399765B2 (en) 2003-09-19 2008-07-15 Abbott Laboratories Substituted diazabicycloalkane derivatives
JP2007510642A (ja) 2003-11-03 2007-04-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 中枢神経系障害の治療のための新規ノルエピネフリン再取込み阻害薬
NZ553622A (en) 2004-10-20 2010-08-27 Neurosearch As Novel diazabicyclic aryl derivatives and their medical use
DK1805158T3 (en) 2004-10-29 2018-08-06 Kalypsys Inc SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR
WO2006087306A2 (en) 2005-02-16 2006-08-24 Neurosearch A/S Diazabicyclic aryl derivatives and their use as cholinergic ligands at the nicotinic acetylcholine receptors
EP1963323B1 (en) 2005-12-06 2010-07-14 Neurosearch A/S Novel diazabicyclic aryl derivatives and their medical use
US7700596B2 (en) 2006-02-10 2010-04-20 Neurosearch A/S 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
JP2009526024A (ja) 2006-02-10 2009-07-16 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体アゴニストとしての３−ヘテロアリール−３，９−ジアザビシクロ［３．３．１］ノナン誘導体

Also Published As

Publication number Publication date
WO2007090887A1 (en) 2007-08-16
US20080306078A1 (en) 2008-12-11
JP2009526023A (ja) 2009-07-16
EP1984366A1 (en) 2008-10-29
EP1984366B1 (en) 2010-12-15
US7687517B2 (en) 2010-03-30
CA2641683A1 (en) 2007-08-16

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ 3,9-DIAZABICYCLO [3.3. 1]NONANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ FROM 3,9-DIAZABICYCLO [3.3. 1]NONANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS TO: 3,9-DIAZABICYCLO[3.3.1]NONANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application