AU2007200955A1 - Multi-chamber container - Google Patents

Multi-chamber container Download PDF

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Publication number
AU2007200955A1
AU2007200955A1 AU2007200955A AU2007200955A AU2007200955A1 AU 2007200955 A1 AU2007200955 A1 AU 2007200955A1 AU 2007200955 A AU2007200955 A AU 2007200955A AU 2007200955 A AU2007200955 A AU 2007200955A AU 2007200955 A1 AU2007200955 A1 AU 2007200955A1
Authority
AU
Australia
Prior art keywords
cover
chamber container
chamber
container
filling chambers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2007200955A
Other versions
AU2007200955B2 (en
Inventor
Toshiya Okahisa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Baylor College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine
Publication of AU2007200955A1 publication Critical patent/AU2007200955A1/en
Application granted granted Critical
Publication of AU2007200955B2 publication Critical patent/AU2007200955B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093Containers having several compartments for products to be mixed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202Separating means
    • A61J1/2024Separating means having peelable seals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202Separating means
    • A61J1/2034Separating means having separation clips

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Bag Frames (AREA)
  • Package Specialized In Special Use (AREA)

Description

Regulation 3.2
AUSTRALIA
Patents Act 1990 COMPLETE SPECIFICATION STANDARD PATENT
APPLICANT:
Invention Title: Baylor College of Medicine MULTI-CHAMBER CONTAINER The following statement is a full description of this invention, including the best method of performing it known to me: MULTI-CHAMBER CONTAINER FIELD OF THE INVENTION The present invention relates to a multi-chamber container, and more particularly, to a multi-chamber container which accommodates two or more solutions to enable the solutions to be mixed.
BACKGROUND OF THE INVENTION Conventionally, in the case of mixing two or more solutions, in order to prevent the solutions from deteriorating with time due to the interaction, the solutions have been mixed and adjusted immediately before administration in medical fields. However, such mixing of solutions immediately before administration has defects such as contamination with microorganisms and/or intrusion of a foreign substance, malpractice mixing, inability of prompt administration and the like.
Therefore, such a multi-chamber container is currently being developed that the container is provided with barrier which separates the solutions, such as a seal which can be peeled by application of pressure, and that each of a plurality of chambers partitioned by the barrier is filled with a respective unmixed solution. In this multi-chamber container, the barrier is released immediately before administration to mix the solutions.
As a method of releasing the barrier to mix solutions in such a multi-chamber container, there are a method of pressing a filling chamber by hand or the like to decrease the volume of the chamber, and thereby releasing the barrier by pressure of the solution inside the chamber to mix the solutions, another method of providing an injection plug extending from a filling chamber to another filling chamber through the barrier, and opening the injection plug to mix the solutions, and the like.
In such mixing methods, opening operation (pressing or opening of the plug) is necessary independently of mounting operation in mounting the container to a predetermined device to administer. A possibility thereby arises that solutions are administered without performing the opening operation. Further, it is difficult to confirm that the barrier is released and the solutions are mixed, making it difficult to find that the opening operation is not performed. Furthermore, in a type of opening a plug to mix solutions, the opened plug is left in the chamber, resulting in a problem of intrusion of the foreign substance.
SUMMARY OF THE INVENTION It is an object of the present invention to provide a multi-chamber container that prevents an occurrence of forgetting to mix solutions while enabling intrusion of a foreign substance to be prevented.
A multi-chamber container of the invention is a multi-chamber container which accommodates a plurality of solutions, is divided into a plurality of filling chambers by an opening preventing portion, and has a container body with the filling chambers filled with the solutions respectively, and a covering member that covers at least one of the filling chambers of the container body, where the covering member has a pair of rigid members that sandwich the opening preventing portion from the outside, and seal portions provided to close the pair of rigid members.
BRIEF DESCRIPTION OF THE DRAWINGS FIG.1 is a front view showing a multi-chamber container according to an embodiment of the present invention; FIG.2 is a side view of the multi-chamber container shown in FIG.l; FIG.3 is an enlarged view showing a cover attaching portion of the multi-chamber container shown in FIG.l; FIGs.4A to 4C are views showing an aspect where a cover is attached to the multi-chamber container according to the embodiment of the invention; is a front view showing another example of the multi-chamber container according to the embodiment of the invention; and FIG.6 is a front view showing still another example of the multi-chamber container according to the embodiment of the invention.
DETAILED DESCRIPTION OF THE INVENTION An embodiment of the present invention will specifically be described below with reference to accompanying drawings.
FIG.l is a front view showing a multi-chamber container according to an embodiment of the present invention. FIG.2 is a side view of the multi-chamber container shown in FIG.l. FIG.3 is an enlarged view of a cover attaching portion of the multi-chamber container shown in FIG.1.
The multi-chamber container as shown in FIG.1 has a container body i. The container body 1 has a plurality of (two in this embodiment) filling chambers 11, 12. A seal portion 13 is provided between the filling chambers 11, 12 to prevent opening of communication of solutions respectively filled in the filling chambers 11, 12.
Accordingly, the container body 1 is divided into two filling chambers 11, 12 by the seal portion 13.
The seal portion 13 has sufficient pressure resistance to a pressure in the normal direction (direction of the arrow A) to the sheet. In other words, the pressure from the direction of the arrow A is dispersed over the entire container body 1, and the seal portion 13 is thereby not peeled. Meanwhile, the seal portion 13 has a property of easily peeling against the force in the vertical direction (direction of the arrow B) of the sheet. By using such a seal portion 13 as an opening tpreventing portion, when the pressure in the direction n of the arrow B is applied to the seal portion 13 by applying the pressure to at least one of the filling chambers 11, t 5 12, the seal portion 13 is peeledtoopenthe communication In between the filling chambers 11, 12, and the solutions filled into the chambers 11, 12 are mixed.
The container body 1 has a hole 14 to be hanged in a stand during administration of the solutions at its one end (upper position in the figure). Further, the container body 1 has a cock 15 at the other end (lower position in the figure) The cock 15 is sealed by a rubber stopper until a hollow needle is inserted.
In addition, generally used materials may be used as a material for the container body i.
The multi-chamber container as shown in FIG.I has a cover 2 that covers at least one of the filling chambers 11, 12 (the chamber 12 in FIG.1). The cover 2 is only required to cover at least an end portion (for example, the cock 15 or hole 14) The cover 2 includes a pair of rigid members 21 that sandwich the seal portion 13 from the outside, and seal portions 22 provided to close the pair of rigid members 21. As the cover 2, a film, sheet and the like may be used which are formed of paper, plastic or the like.
The rigid members 21 have sufficient ridigity to hold the seal portion 13 from the outside to enable the cover 2 to be attached to the container body i. As the rigid members 21, plates and the like may be used which canpinch the sealportion 13 (thin portionof the container body 1) along the seal portion 13. It is preferable that the rigid members 21 are light in weight as possible.
Accordingly, as a material for the rigid members, for example, paper, plastic and the like may be used. The rigid members 21 are attached to the internal side of the cover 2 by adhesive or the like to come into contact with the seal portion 13. Further, as in an aspect as shown in FIG.l, since the cover 2 is closed by the seal portions 22, the length L of the rigid member 21 is set shorter than the width D of the cover 2.
The seal portions 22 are provided in regions outside the rigid members 21 in the cover 2. The seal portions 22 have adhesion of the extent to which the seal portions 22 peel by an increase in thickness of the seal portion 13 when the seal portion 13 peels to cause the filling chambers 11, 12 to be opened in therebetween and increases its thickness. In other words, the adhesion and shape of the seal portions 22, and positions of the sealportions 22 in the cover 2 are set so as to hold the cover when the filling chambers 11, 12 arenotopenedintherebetween, while causing the cover 2 to easily drop when the filling chambers 11, 12 are opened in therebetween and the thickness of the seal portion 13 increases.
The seal portions 22 may be formed of a double-faced tape, the cover 2 may be melted to form the seal portions 22, or engaging portions may be provided at contact portions (end portions) of the cover 2 and engaged to form the seal portions 22.
In the case of attaching the cover 2 to the container body i, prepared first is the cover 2 (for example, film or sheet) as shown in FIG.4A. Rigid members 21 (for example, plates) are respectively attached to both end portions on one surface of the cover 2. Then, as shown in FIG.4B, the cover 2 is bent so that the rigid members 21 are opposed to each other. In this state, the bent cover 2 is put on the container body 1 so as to cover one (the chamber 12) of the filling chambers of the container body 1 so that positions of the rigid members 21 are in accordance with the position of the seal portion 13. Next, as shown in FIG.4C, regions outside the rigid members 21 are sealed to form the seal portions 22.
Thus, the aforementioned multi-chamber container is configured so that the filling chamber 12 is covered with the cover 2 when the filling chambers 11, 12 are not opened in therebetween, and that the cover 2 drops when the fillingchambers 11, 12 areopenedintherebetween and the seal portion 13 increases its thickness.
Therefore, when the filling chambers 11, 12 are not opened in therebetween, the cock 15 of the container body 1 is covered with the cover 2. Hence, in this state, since the cock 15 is covered with the cover 2, it is logically not possible to inject a hollow needle into the cock to use the container. In other words, the container cannot be used with the filling chambers 11, 12 not opened in therebetween. It is thus possible to reliably avoid anoccurrenceof forgettingtomixthe solutions. Further, according tothis configuration, it ispossible to prevent intrusion of a foreign substance.
In an aspect as shown in FIG.1, the case is described that side portions of the cover 2 are opened as shown in FIG.4C. However, in the present invention, the cover 2 may be configured so that the side portions of the cover 2 are closed by perforations to be torn off, and the perforations are torn to cause the cover 2 to drop when the thickness of the seal portion 13 increases with the filling chambers 11, 12 opened in therebetween. In this case, the seal portions 22 may beprovidedor notprovided.
is a front view showing another example of the multi-chamber container according to this embodiment of thepresent invention. In themulti-chamber container as shown in FIG.5, the filling chamber 11 is covered with the cover 2. A configuration of the cover 2 is the same as that in the multi-chamber container as shown in FIG.1.
The multi-chamber container as shown in FIG.5 is configured so that the filling chamber 11 is covered with the cover 2 when the filling chambers 11, 12 are not opened intherebetween, andthat the cover2 dropswhen the filling chambers 11, 12 are opened in therebetween and the seal portion 13 increases its thickness. Therefore, when the filling chambers 11, 12 are not opened in therebetween, the hole 14 of the container body 1 is covered with the cover2. Hence, in this state, since the hole 14 is covered with the cover 2, the container cannot be hung in a stand logically nor cannot be used. In other words, the container cannot be used with the filling chambers 11, 12 not opened in therebetween. It is thus possible to reliably avoid an occurrence of forgetting to mix the solutions. Further, according to this configuration, it is possible to prevent intrusion of a foreign substance.
FIG.6 is a front view showing still another example of the multi-chamber container according to this embodiment of the present invention.
In the multi-chamber containers as shown in FIG.l and FIG.5, the cover 2 is sealed to form the seal portions 22. In the multi-chamber container as shown in FIG.6, the rigid members 21 are sealed to form the seal portions 22. Accordingly, in an aspect as shown in FIG.6, since the cover 2 is closed by the rigid members 21, the length L of the rigid members 21 is set longer than the width D of the cover 2. In addition, the rigid members 21 are the same as those in the multi-chamber containers as shown in FIG.I and The multi-chamber container as shown in FIG.6 is configured so that the filling chamber 12 is covered with the cover 2 when the filling chambers 11, 12 are not opened
_I
in therebetween, and that the cover 2 drops when the filling chambers 11, 12 are opened in therebetween and the seal portion 13 increases its thickness. Therefore, when the filling chambers 11, 12 are not opened in therebetween, the cock 15 of the container body 1 is covered with the cover 2. Hence, in this state, since the cockl5 is covered with the cover 2, it is logically not possible to inject a hollow needle into the cock 15 to use the container.
In other words, the container cannot be used with the filling chambers 11, 12 not opened in therebetween. It is thus possible to reliably avoid an occurrence of forgetting to mix the solutions. Further, according to this configuration, it is possible to prevent intrusion of a foreign substance.
In the multi-chamber container as shown in FIG.6, the filling chamber 12 is covered with the cover 2.
However, the filling chamber 11 may be covered with the cover 2 as in the multi-chamber container as shown in using the same cover 2 as shown in FIG.6.
The present invention is not limited to the above-mentioned embodiment, and is capable of being carried into practice with various modifications thereof.
For example, although the above-mentioned embodiment describes the case of two filling chambers, the present invention is applicable to cases of three or more filling chambers. Further, although the above-mentioned embodiment describes the case of filling solutions into filling chambers, the present invention is applicable to cases of filling powdery substances into filling chambers. Further, materials, sizes, shapes andthe like in the above-mentioned embodiment are of examples, and the invention is not limited thereto. Moreover, it will be apparent to those skilled in the art that the present invention may be carried into practice with various modifications thereof without departing from the scope of the invention.
Throughout this specification and the claims, unless the context requires otherwise, the word "comprise" and its variations, such as "comprises" and "comprising," will be understood to imply the inclusion of a stated integer or step or group of integers or steps but not the exclusion of any other integer or step or group of integers or steps.
The reference to any prior art in this specification is not, and should not be taken as an acknowledgement or any form of suggestion that such art forms part of the common general knowledge in Australia.

Claims (7)

  1. 2. The multi-chamber container according to claim i, wherein one of the filling chambers is covered with the covering member when the filling chambers are not opened in therebetween, and the covering member drops when the filling chambers are opened in therebetween and a thickness of the opening preventing portion increases.
  2. 3. The multi-chamber container according to claim i, wherein the pair of rigid members are plates.
  3. 4. The multi-chamber container according to claim i, wherein the container body has a cock at its one end, and a hole at the other end to hang the container body. The multi-chamber container according to claim 4, wherein the covering member covers at least the one end.
  4. 6. The multi-chamber container according to claim 4, wherein the covering member covers at least the other end.
  5. 7. The multi-chamber container according to claim 1, wherein lengths of the rigid members are shorter than a width of the covering member.
  6. 8. The multi-chamber container according to claim 1, wherein lengths of the rigid members are longer than a width of the covering member.
  7. 9. A multi-chamber container substantially as herein described.
AU2007200955A 2006-03-13 2007-03-05 Multi-chamber container Ceased AU2007200955B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/375,188 2006-03-13
US11/375,188 US20070209951A1 (en) 2006-03-13 2006-03-13 Multi-chamber container

Publications (2)

Publication Number Publication Date
AU2007200955A1 true AU2007200955A1 (en) 2007-09-27
AU2007200955B2 AU2007200955B2 (en) 2012-10-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007200955A Ceased AU2007200955B2 (en) 2006-03-13 2007-03-05 Multi-chamber container

Country Status (5)

Country Link
US (1) US20070209951A1 (en)
EP (1) EP1834623B1 (en)
JP (1) JP5361138B2 (en)
AU (1) AU2007200955B2 (en)
HK (1) HK1102541A1 (en)

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US9358135B2 (en) * 2007-04-17 2016-06-07 Warsaw Orthopedic, Inc. Devices, methods and systems for hydrating a medical implant material
JP2009142414A (en) * 2007-12-13 2009-07-02 Fuji Seal International Inc Dual-cell drug bag sealing body
EP2382052B1 (en) * 2009-01-23 2013-01-16 Akzo Nobel Coatings International B.V. Packaging for two or more fluids
JP6626264B2 (en) * 2015-03-31 2019-12-25 株式会社大塚製薬工場 Incorrect administration prevention device for infusion bag and infusion bag provided with the same

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US4994056A (en) * 1989-11-09 1991-02-19 Ikeda Daniel P Unit dose medicament storing and mixing system
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US20010047162A1 (en) * 2000-02-17 2001-11-29 Yasumi Yugari Injection kit and injection device
JP2002136570A (en) * 2000-08-24 2002-05-14 Otsuka Pharmaceut Factory Inc Medical double-chamber container
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JP4178917B2 (en) * 2002-11-11 2008-11-12 ニプロ株式会社 Multi-chamber container
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US7243787B2 (en) * 2003-03-26 2007-07-17 Nipro Corporation Medicine bag
EP1491177A1 (en) * 2003-06-27 2004-12-29 Nipro Corporation Displaceable-plug-containing filling/discharging port and medical container having the same
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JP4179218B2 (en) * 2003-09-30 2008-11-12 ニプロ株式会社 Medical container
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JP4600725B2 (en) * 2004-02-02 2010-12-15 有限会社ケーアールビジネス Medical multi-chamber container with unopened use prevention mechanism
JP4587096B2 (en) * 2004-03-03 2010-11-24 有限会社ケーアールビジネス Medical multi-chamber container with unmixing prevention mechanism
JP4609791B2 (en) * 2004-08-10 2011-01-12 有限会社ケーアールビジネス Multi-chamber container
JP3118291U (en) * 2005-09-30 2006-01-26 株式会社大塚製薬工場 Hanging cover

Also Published As

Publication number Publication date
US20070209951A1 (en) 2007-09-13
EP1834623A3 (en) 2009-02-11
EP1834623B1 (en) 2012-04-18
EP1834623A2 (en) 2007-09-19
JP2007244864A (en) 2007-09-27
HK1102541A1 (en) 2007-11-30
JP5361138B2 (en) 2013-12-04
AU2007200955B2 (en) 2012-10-25

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired